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Oral cavity spray for inhibiting pathogenic bacteria in oral cavity, and applications thereof

An oral spray, pathogenic bacteria technology, applied in the application, aerosol delivery, local antibacterial agent and other directions, to achieve the effect of facilitating production and preparation, improving bacteriostatic effect, and inhibiting oral disease pathogenic bacteria

Active Publication Date: 2018-02-23
孙自乐
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] So far, there have been no reports about extracting leaf lettuce polysaccharides and using them to make oral sprays to effectively prevent and treat oral diseases

Method used

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  • Oral cavity spray for inhibiting pathogenic bacteria in oral cavity, and applications thereof
  • Oral cavity spray for inhibiting pathogenic bacteria in oral cavity, and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] 1 Experimental materials

[0033] Leaf lettuce variety Qianwei 75, eggs: purchased at the vegetable market.

[0034] Reagents: sodium bicarbonate, sodium benzoate, hydroxypropyl methylcellulose, hyaluronic acid, xanthan gum, purchased from Sinopharm Chemical Reagent Co., Ltd.; vitamin C, purchased from Nanjing Chemical Reagent Co., Ltd.; peppermint oil, lemon oil, purchased from Shanghai Jianglai Biotechnology Co., Ltd.

[0035] Equipment: DU-640 UV / Vis spectrophotometer: Beckman Company of the United States; AUW320 analytical balance: Shimadzu, Japan; MA-2270EGC Haier microwave oven: Qingdao Haier Microwave Products Co., Ltd.; FW100 high-speed pulverizer: Beijing Zhongxing Weiye Instrument Co., Ltd. ; RE52CS rotary evaporator: Shanghai Yarong Biochemical Instrument Factory; DZF vacuum drying oven: Shanghai Haixiang Instrument Equipment Factory; 800-type desktop centrifuge: Shanghai Surgical Instrument Factory.

[0036] Bacterial strains: Streptococcus mutans CGMCC125...

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PUM

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Abstract

The present invention relates to an oral cavity spray for inhibiting pathogenic bacteria in oral cavity, and applications thereof, wherein the oral cavity spray contains, by weight, 5-10% of Romaine lettuce polysaccharide, 1-2% of sodium bicarbonate, 1-2.5% of sodium benzoate, 1-2.5% of vitamin C, 5-10% of peppermint oil and lemon oil, 3-6% of hydroxypropylmethylcellulose, hyaluronic acid and xanthan gum, and the balance of water. According to the present invention, the bacterial coating spraying experiment results show that the oral cavity spray can effectively inhibit the activities of Streptococcus mutans and Streptococcus sobrinus, such that the oral cavity spray can effectively attached to the tooth medium so as to inhibit oral cavity disease pathogenic bacteria.

Description

technical field [0001] The invention relates to medicines and health care products for preventing and treating oral diseases, in particular to an oral spray for inhibiting oral pathogenic bacteria and its application. Background technique [0002] Oral disease is a general term for a class of diseases with a high incidence rate. Common ones include dental caries, bad breath, toothache, and bleeding gums. There are a large number of microorganisms in the human oral cavity, including pathogenic bacteria, non-pathogenic bacteria and opportunistic pathogenic bacteria, and the specific types are quite complicated. Common bacteria include Staphylococcus, Streptococcus, Streptococcus sialobacter, Neisseria, Vanillium, Corynebacterium, Actinomyces israeli, Spirulina sputum, Vibrio sputum, Borrelia spirochete, etc., the most important Streptococcus, Staphylococcus and Lactobacillus. There are weakly alkaline saliva and food residues in the mouth, which provide suitable conditions f...

Claims

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Application Information

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IPC IPC(8): A61K9/12A61K47/38A61K47/36A61K47/44A61K31/715A61P31/04A61P31/02A61P1/02A23L33/125A23L33/15A23L33/16A23L33/12C08B37/00
CPCA23L33/12A23L33/125A23L33/15A23L33/16A23V2002/00A61K9/006A61K9/12A61K31/715A61K47/36A61K47/38A61K47/44C08B37/0003A23V2200/30A23V2250/50A23V2250/708A23V2250/5108
Inventor 刘锐
Owner 孙自乐
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