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Lung clearing and phlegm eliminating oral liquid for children and preparation method thereof

A technology for clearing the lungs, reducing phlegm, and oral liquid, which is applied in the field of medicine, can solve problems such as precipitation, and achieve the effect of solving the difficulty of medication

Inactive Publication Date: 2018-02-23
SUNFLOWER PHARMA GRP JIZHOU
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

On the basis of not affecting the various indicators of the original standard, a stabilizer was added during the preparation process, which solved the problem that the oral liquid was prone to precipitation after being placed for a long time, improved the stability of product quality, and screened out products with fruity taste formulations that improve children's compliance with medication

Method used

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  • Lung clearing and phlegm eliminating oral liquid for children and preparation method thereof
  • Lung clearing and phlegm eliminating oral liquid for children and preparation method thereof
  • Lung clearing and phlegm eliminating oral liquid for children and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] According to the preparation method in the summary of the invention

[0046] Prescription: 90 parts of Ephedra, 225 parts of Peucedanum, 225 parts of Scutellaria baicalensis, 225 parts of fried perilla seeds, 675 parts of gypsum, 225 parts of fried bitter almonds, 279 parts of Tinglizi, 225 parts of Zhuru, 100 parts of sucrose, 200 parts of honey , 2 parts of sorbic acid, 5 parts of cantaloupe essence, 36 parts of glycerin

[0047] Preparation method: Take the prescribed amount of gypsum, add 8-10 times the amount of water and decoct for 1 hour, add ephedra and other seven-flavored medicinal materials, make up the amount of water to 8-10 times the amount of medicinal materials and decoct twice, each time for 1 hour, and combine the decoction , filtered. Concentrate the filtrate to a clear paste with a relative density of 1.18-1.22 (50°C), add ethanol to make the alcohol content reach 50-80%, stir well, refrigerate and stand for 48 hours, filter, and recover the ethanol...

Embodiment 2

[0049] Prescription: 90 parts of Ephedra, 225 parts of Peucedanum, 225 parts of Scutellaria baicalensis, 225 parts of fried perilla seeds, 675 parts of gypsum, 225 parts of fried bitter almonds, 279 parts of Tinglizi, 225 parts of Zhuru, 100 parts of sucrose, 200 parts of honey , 2 parts of sorbic acid, 5 parts of peach flavor, 72 parts of propylene glycol

[0050] Preparation method: Take the prescribed amount of gypsum, add 8-10 times the amount of water and decoct for 1 hour, add ephedra and other seven-flavored medicinal materials, make up the amount of water to 8-10 times the amount of medicinal materials and decoct twice, each time for 1 hour, and combine the decoction , filtered. Concentrate the filtrate to a clear paste with a relative density of 1.18-1.22 (50°C), add ethanol to make the alcohol content reach 50-80%, stir well, refrigerate and stand for 48 hours, filter, and recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell. Co...

Embodiment 3

[0052] Prescription: 90 parts of Ephedra, 225 parts of Peucedanum, 225 parts of Scutellaria baicalensis, 225 parts of fried perilla seeds, 675 parts of gypsum, 225 parts of fried bitter almonds, 279 parts of Tinglizi, 225 parts of Zhuru, 100 parts of sucrose, 200 parts of honey , 2 parts of sorbic acid, 5 parts of peach essence, 36 parts of hydroxypropyl-β-cyclodextrin

[0053]Preparation method: Take the prescribed amount of gypsum, add 8-10 times the amount of water and decoct for 1 hour, add ephedra and other seven-flavored medicinal materials, make up the amount of water to 8-10 times the amount of medicinal materials and decoct twice, each time for 1 hour, and combine the decoction , filtered. Concentrate the filtrate to a clear paste with a relative density of 1.18-1.22 (50°C), add ethanol to make the alcohol content reach 50-80%, stir well, refrigerate and stand for 48 hours, filter, and recover the ethanol from the filtrate under reduced pressure until it has no alcoho...

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Abstract

The invention belongs to the technical field of medicines, and in particular relates to an oral liquid for clearing lung and resolving phlegm for children and a preparation method thereof. The product is made of 80-100 parts of ephedra, 210-240 parts of Peucedanum, 210-240 parts of Scutellaria baicalensis, 210-240 parts of fried perilla seeds, 660-690 parts of gypsum, 210-240 parts of fried bitter almonds, and 210-240 parts of fried bitter almonds. 260-290 parts, 210-240 parts of Zhuru, 90-110 parts of sucrose, 180-220 parts of honey, 1.5-3 parts of sorbic acid, 1-10.5 parts of essence, 2-450 parts of stabilizer, prepared by scientific methods . In the preparation process of the present invention, each intermediate medicinal liquid has been pretreated, and a stabilizer has been added to improve the clarity of the oral liquid, overcome the ubiquitous occurrence of precipitation after long-term placement in the oral liquid of traditional Chinese medicine, and improve the This ensures the stability of product quality; at the same time, it screens out products with fruit flavors, which improves the compliance of children taking medicine.

Description

technical field [0001] The invention relates to the technical field of medicine, and more specifically relates to an oral liquid for clearing lung and resolving phlegm for children and a preparation method thereof. Background technique [0002] Acute bronchitis is a common respiratory disease in children, especially in infants and young children, the incidence rate is the highest, and its pathogens are various viruses and bacteria, or their co-infection. Acute bronchitis belongs to exogenous cough in traditional Chinese medicine, most of which are caused by the external invasion of the six evils. Susceptible to exogenous wind-heat, so in clinical practice, wind-heat invading the lung is the most common symptom. Generally, symptomatic treatment is carried out for dispelling wind and clearing heat, clearing lung, resolving phlegm, relieving cough and relieving asthma. [0003] Xiaoer Qingfei Huatan Oral Liquid belongs to the varieties recorded in the national drug standards. ...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K9/08A61K47/10A61K47/40A61P11/00A61P11/10A61K33/06
CPCA61K36/899A61K9/0095A61K33/06A61K36/17A61K36/23A61K36/31A61K36/535A61K36/539A61K36/736A61K47/10A61K47/40A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 潘辉闫翠娥贾金和
Owner SUNFLOWER PHARMA GRP JIZHOU
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