Gentiana macrophylla capsule fingerprint spectrum and application of spectrum to quality control and component analysis

A technology of fingerprint and capsule, applied in the field of drug analysis, to achieve the effect of good analysis and evaluation ability
CN107796892AActive Publication Date: 2018-03-13XIAN C P PHARMA
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
XIAN C P PHARMA
Publication Date
2018-03-13

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Abstract

The invention relates to a gentiana macrophylla capsule fingerprint spectrum and an application of the spectrum to quality control and component analysis. According to the spectrum, a HPLC (high-performance liquid chromatography) fingerprint spectrum common mode of a gentiana macrophylla capsule is determined by the aid of a traditional Chinese medicine chromatographic fingerprint spectrum similarity evaluation system (2004A), 23 common peaks are calibrated, similarity is 0.966-0.982, and the content of loganic acid, shanzhiside methyl ester, 6'-O-beta-D-glucose gentiopicroside, swertiamarin,gentiopicroside, sweroside, isoorientin and isovitexin in 10 preparations is measured. According to the spectrum, a HPLC fingerprint spectrum method of the gentiana macrophylla capsule and a content measuring method are built, the method has good analysis evaluation ability and the advantages of accuracy, convenience, stability, reliability and the like, so that the method can serve as an effective evaluation method for the quality of the preparation.
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Description

technical field

[0001] The invention belongs to the field of drug analysis, in particular to the fingerprint of Jilong capsules and its application in quality control and component analysis. Background technique

[0002] The main component of Jilong Capsules is the extract of natural plant medicinal material Qinjie, which is mainly used for clearing the liver and releasing heat. [1] . Gentianamacrophylla (Gentianamacrophylla) is a plant of the Gentianaceae family. Its root is one of the important traditional Chinese medicinal materials in my country. It was first recorded in the "Shen Nong's Materia Medica". pee. Shaanxi and Gansu are the authentic producing areas of qinjie medicinal materials [2] . At present, the technical process of Jilong capsules produced by our company is as follows: Qinjing is permeated with 80% ethanol, then passed through a D101 type macroporous adsorption resin column, eluted with 30% ethanol, concentrated under reduced pressure of the eluent, d...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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