Red rice yeast bacterial strain culture medium used for increasing yield of Monat Klin

Abstract

The invention discloses a red rice yeast bacterial strain culture medium used for increasing yield of Monat Klin, containing the following materials in parts by weight: malt, potato, corn starch, glucose, glycerol, agar, lactic acid, absolute ethyl alcohol, sodium acetate, soy peptone, phosphate, calcium chloride, a folia perillae acutae concentrated solution, functional yeast, multi-bacteria compound enzyme and sterile glacial acetic acid. According to the invention, a mixed thick slurry prepared from malt, potato and agar as main components is induced by glycerol, high-density growth of cells in the thick slurry is promoted by glucose, and then the thick slurry is induced to perform self protein expression by glycerol, so as to further promote cell growth, increase the protein expressionquantity, and increase the activity of red rice yeast in the culture medium in culture of a red rice yeast bacterial strain, thus effectively promoting metabolism of Monat Klin K, and increasing theyield of Monat Klin K.

Description

technical field [0001] The invention relates to a culture medium for monascus strains used for increasing monacrine production. Background technique [0002] At present, cancer has become a major killer threatening human health around the world. Western medicine is the main treatment method, including surgery, radiotherapy and chemotherapy, etc., all of which have strong side effects. However, until now, cancer can only be controlled by drugs. Compared with the previous anti-cancer drugs, the newly developed anti-cancer functional red yeast rice can maintain a higher blood concentration in the body, thereby improving the anti-cancer activity . And there is no drug toxicity, convenient administration, only oral administration, patients do not need to be hospitalized, and the quality of life is improved. Anti-cancer functional red yeast rice has remarkable curative effect, and is a safe, effective, natural, green and zero-toxic oral anti-cancer drug. [0003] At present, fu...

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Problems solved by technology

[0003] At present, functional red yeast rice is traditionally fermented and cultivated using rice as a substrate, and oats, barley or yam are also used as substrates for cultivation. However, the nutrient composition of a single substrate is not completely suitable for the growth and The metabolism of monacolin K, and the powdery material is likely to cause the solid medium to agglomerate during the fermentation process, which is not conducive to the heat dissipation and ventilation of the medium matrix, so that some raw materials will still exist after the fermentation of the medium, resulting in red The yield of Aspergillus strain is low, which in turn affects the slow metabolism of monacolin K and reduces the yield of monacolin K

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