Multifunctional nucleic acid testing device

A detection device and multi-functional technology, applied in the field of multi-functional nucleic acid detection devices, can solve the problems of using fluorescent probes for detection cost, affecting sample detection results, expensive equipment, etc., achieving good driving effect, avoiding cross-contamination, and easy accuracy The effect of control

Pending Publication Date: 2018-04-27
广州市宝创生物技术有限公司
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  • Abstract
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Problems solved by technology

In the traditional process of nucleic acid amplification detection, it is common to have false positive test results due to cross-contamination of amplification products
Moreover, most of the templates used in traditional nucleic acid amplification detection methods need to go through an independent sample extraction step, and this step is also likely to cause template cross-contamination and affect the judgment of sample test results.
At present, there are some integrated nucleic acid detection devices on the market, such as GeneXpertSystem, etc., which can realize the extraction, amplification and detection

Method used

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Embodiment Construction

[0038] In order to facilitate the understanding of the present invention, the present invention will be described more fully below with reference to the associated drawings. Preferred embodiments of the invention are shown in the accompanying drawings. However, the present invention can be embodied in many different forms and is not limited to the embodiments described herein. On the contrary, these embodiments are provided to make the understanding of the disclosure of the present invention more thorough and comprehensive.

[0039] It should be noted that when an element is referred to as being “fixed” to another element, it can be directly on the other element or there can also be an intervening element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or intervening elements may also be present.

[0040] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as...

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Abstract

The invention discloses a multifunctional nucleic acid detection device, which comprises a base, a transmission mechanism, a liquid suction mechanism, a suction mechanism and a shell sealed with the base. By arranging multiple liquid tanks on the base, multiple functions can be integrated, such as nucleic acid extraction, amplification and detection, or amplification and detection of at least one extracted target template. The multi-functional nucleic acid detection device forms an independent cavity through the base and the shell sealing, and the liquid suction mechanism can be switched between different liquid tanks through the transmission mechanism, liquid suction mechanism and suction mechanism carried by the operating device. And it can realize liquid suction or discharge in different liquid tanks. The multifunctional nucleic acid detection device has a simple structure, can realize small volume, can integrate multiple functions into one body during nucleic acid detection, is easy to operate, and can enable nucleic acid detection to be used in more medical environments that lack professional technicians and experimental conditions. It is beneficial to the application and promotion of nucleic acid detection.

Description

technical field [0001] The invention relates to the field of molecular biology detection, in particular to a multifunctional nucleic acid detection device. Background technique [0002] Nucleic acid amplification detection has been widely used in biomedicine and other fields. In the traditional process of nucleic acid amplification detection, it is common for false positive detection results to be caused by cross-contamination of amplified products. Moreover, most of the templates used in traditional nucleic acid amplification detection methods need to go through an independent sample extraction step, and this step is also likely to cause template cross-contamination and affect the judgment of sample test results. At present, there are some integrated nucleic acid detection devices on the market, such as GeneXpertSystem, etc., which can realize the extraction, amplification and detection of the nucleic acid to be tested in a closed system, which greatly avoids the contamina...

Claims

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Application Information

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IPC IPC(8): C12M1/34C12M1/00G01N35/10
CPCG01N35/1009C12Q1/6806C12Q1/686
Inventor 邹秉杰王建平
Owner 广州市宝创生物技术有限公司
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