3 results about "Nucleic Acid Testing" patented technology

This invention discloses a household-use, fully enclosed thermos for COVID-19 nucleic acid testing. Based on loop-mediated isothermal amplification (RT-LAMP) technology, it integrates the entire nucleic acid testing process and post-testing sterilization into a constant-temperature, negative-pressure thermos. The testing process is observed and analyzed via a mobile app using a smartphone camera, and the results are displayed on a screen. The device can also connect to a mobile app to upload test results. The testing process requires the necessary experimental materials for RT-LAMP. This invention significantly reduces costs compared to the RT-PCR method, while offering portability and a simpler operating procedure.

The present application relates to a chip, a preparation method therefor, and an application thereof. The chip of embodiments of the present application comprises: a substrate having a surface grafted with an amino group, the amino group being a primary amino group or a secondary amino group; and a first compound linked to the surface via the amino group, the first compound comprising the following structure, i.e., formula (1) or formula (2), wherein R1 and R2 are each independently selected from —OH or C1-C5 alkoxy, and n is 1 or 2. The chip can be used for a nucleic acid test, such as single-molecule sequencing and next-generation sequencing.