Functional positioning method for supplementary motor area based on resting state

A positioning method and resting state technology, applied in the field of medical image processing and application, can solve the problems of not being able to meet clinical needs well, poor task execution of brain tumor patients, etc., to improve clinical feasibility, high accuracy, The effect of reducing engagement requirements

Active Publication Date: 2018-05-25
FUDAN UNIV +1
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Problems solved by technology

[0006] The method for functional positioning of the brain auxiliary motor area of ​​the present invention uses resting state functional magnetic resonance imaging technology to automatically locate the auxiliary motor area, uses machine learning algorithms to realize high-precision positioning of the auxiliary motor area, and performs algorithms on multiple data Effectiveness and reliability verification, fully considering the clinical status of brain tumor patients, only requires the minimum participation of the positioned personnel, can be used for brain-assisted motor function area positioning of healthy people and brain tumor patients, this method can overcome the task-based paradigm The current magnetic resonance positioning technology can only activate the brain functional areas to a limited extent, especially when the task performance of brain tumor patients is generally poor, it cannot well meet the clinical needs.

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  • Functional positioning method for supplementary motor area based on resting state
  • Functional positioning method for supplementary motor area based on resting state

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Embodiment 1

[0026] In this embodiment, taking the positioning of the right SMA brain area as an example, it is necessary to start from the left (affected side) SMA and locate the target of the right (affected side) SMA, while considering that the SMA brain area located on the affected side may be Due to the deformation or displacement of the tumor, the functional localization of the supplementary motor area based on resting-state magnetic resonance imaging was carried out.

[0027] The inventor's machine research team used resting-state functional magnetic resonance technology to obtain 5-minute resting-state functional images and high-precision structural images of patients with gliomas in brain functional areas, and adopted multiple preprocessing: scanning layer time correction, head movement correction , mapped to the standardized space, detrending term, band-pass filtering and Scrubbing; at the same time of registration, remove its influence on the standardization through the tumor MAS...

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Abstract

The invention belongs to the field of medical image processing and application, and relates to a functional positioning technology for the brain supplementary motor area, in particular to a method forautomatically positioning the supplementary motor area with the resting-state functional magnetic resonance imaging technology. According to the method, the supplementary motor area is automaticallypositioned with the resting-state functional magnetic resonance imaging technology, high-accuracy positioning of the supplementary motor is achieved with the machine learning algorithm, algorithm effectiveness and reliability are verified on multiple pieces of data, the clinic state of a brain tumor patient is fully considered, and the method can be used for positioning the brain supplementary motor functional area of a healthy person or the brain tumor patient only through the lowermost participation degree of a positioned person; the defects that the brain functional area often can only be limitedly activated based on the task-paradigm magnetic resonance positioning technology, and particularly when the task execution level of the brain tumor patient is poor, the clinical requirements cannot be well met are overcome.

Description

technical field [0001] The present invention relates to the field of medical image processing and application, and relates to a technology for functional positioning of the auxiliary motor area of ​​the brain, in particular to a resting state-based auxiliary motor area function positioning method, and in particular to a method for functional magnetic resonance imaging using resting state A method for the automatic positioning of the assistive motor zone by technology. Background technique [0002] According to reports, glioma is the most common central nervous system tumor. Statistics show that in my country, the annual incidence of glioma is 3-6 per 100,000 people, and the annual death toll reaches 30,000. At present, among clinical interventions, intracranial surgery is the most direct and effective treatment for glioma. Clinical practice shows that for tumors that occur near the language and motor functional areas of the brain, surgical resection is likely to cause dama...

Claims

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Application Information

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IPC IPC(8): A61B5/055
CPCA61B5/0042A61B5/055A61B5/72A61B5/7264A61B2576/026
Inventor 冯建峰吴劲松罗强朱凤平哈元恺庄冬晓章捷龚方源毛颖阮洪涛
Owner FUDAN UNIV
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