a drug balloon

A technology of balloons and drugs, which is applied in the field of medical devices, can solve the problems of drug loss, low drug utilization rate, poor drug delivery effect, etc., and achieve the effect of preventing a large amount of loss and protecting drugs

Active Publication Date: 2022-07-15
董鹏
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, in the operation of treating cardiovascular diseases, the drug balloon is a commonly used hemostatic device. The traditional drug balloon is made by smearing drugs on the balloon body of the expanded balloon on the basis of the dilated balloon. This kind of balloon will rub against the wall of the delivery tube and the wall of the blood vessel during the delivery process, causing a large amount of drug loss. Therefore, the drug utilization rate of the traditional drug balloon is low, and the drug delivery effect is poor.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1, the present invention provides a kind of medicine balloon, refer to figure 1 and figure 2 , including a balloon body 12 and a catheter 11 connected to the balloon body, the outer surface of the balloon body is provided with a drug 13, and the outside of the drug is wrapped with a riboglycan film 14, as a preferred solution , the riboglycan membrane is 2-3 layers, and the drug is: rapamycin, and / or its derivatives.

[0023] The drug balloon provided by the present invention can effectively protect the drug and prevent a large amount of drug loss by arranging a riboglycan film on the outside of the drug; in addition, due to the expansion of the balloon during use, the riboglycan film is attached to the blood vessel wall, which is very difficult for the operation. The sore has the effect of hemostasis. In addition, by arranging a riboglycan film on the outside of the drug, the residence time of the drug in the sore can be prolonged, and the speed of vascula...

Embodiment 2

[0025] Example 2, on the basis of Example 1, in order to facilitate the observation of the in vivo operation, a contrast agent is arranged between the outer surface of the balloon body and the riboglycan film, and the contrast agent can be set by using existing ones. By way, typically, the contrast agent is located inside the drug. As a setup scheme, see Figure 4 and Figure 5 , the outer surface of the balloon body is provided with a first concave portion 18, the contrast agent 19 is located in the first concave portion, and the drug 13 is located around the first concave portion; the balloon is in the inflated state , the diameter of the opening of the first concave portion is smaller than the maximum diameter of the first concave portion, and a protective film can also be provided on the opening of the first concave portion. The riboglycan film is directly used, that is, the thickness of the riboglycan film at the opening of the first depression is greater than that of o...

Embodiment 3

[0026] Example 3, on the basis of Example 1, see Image 6 and Figure 7 , the outer surface of the balloon body is provided with a second concave portion 20, and the drug 13 is located in the second concave portion; when the balloon is in an inflated state, the diameter of the opening of the second concave portion is smaller than the diameter of the second concave portion. The maximum diameter of the second concave part, in this structure, when the balloon is in a contracted state, since the balloon body is elastic, the opening of the first concave part shrinks to almost wrap the medicine, which is more conducive to preventing the loss of the medicine. During the inflation of the balloon, the deformation of the depression pushes out the medicine in the depression and contacts the blood vessel wall. During this process, the riboglycan membrane is also easily expanded and ruptured, which is more conducive to drug application.

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Abstract

The invention relates to a drug balloon, comprising a balloon body and a catheter connected with the balloon body, the outer surface of the balloon body is provided with a drug, and the outer side of the drug is wrapped with a riboglycan film. The drug balloon provided by the present invention can effectively protect the drug and prevent a large amount of loss of the drug by disposing the riboglycan film on the outside of the drug. The sore has a hemostatic effect.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a drug balloon. Background technique [0002] Cardiovascular disease has gradually become the number one killer of human beings, and it has already become the disease with the highest morbidity and disability rate in modern society. At present, there are a large number of high-risk groups of cardiovascular disease in my country, which has attracted great attention. [0003] In the current operation for the treatment of cardiovascular diseases, the drug balloon is a commonly used hemostatic device. The traditional drug balloon is made by smearing drugs on the balloon body of the expanding balloon on the basis of the expanding balloon. This kind of balloon will rub against the wall of the delivery pipeline and the blood vessel during transportation, resulting in a large amount of drug loss. Therefore, the traditional drug balloon has low drug utilization rate and poor drug...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M25/10A61M31/00
CPCA61M25/10A61M31/00A61M2025/1086A61M2025/1079A61M2025/1075A61M2025/105A61M2210/12A61M2210/005
Inventor 董鹏
Owner 董鹏
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