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Traditional Chinese medicine composition and its preparation for treating breast cancer

A composition, breast cancer technology, applied in the direction of drug combination, medical preparations containing active ingredients, pharmaceutical formulations, etc., can solve the problem of insignificant changes in tumor size, shape and activity, no research, no controlled release of preparations, etc. question

Active Publication Date: 2021-11-26
郭晓玲
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although the patient's clinical symptoms can be significantly improved, the quality of life can be improved, and the long-term survival rate has improved, but the effect of traditional Chinese medicine on breast cancer is relatively slow, and the changes in tumor size, shape and activity may be relatively insignificant
Tracing it to its cause, it may be that on the one hand traditional Chinese medicine treats breast cancer only as scrofula and so on, and has not studied it deeply;

Method used

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  • Traditional Chinese medicine composition and its preparation for treating breast cancer
  • Traditional Chinese medicine composition and its preparation for treating breast cancer
  • Traditional Chinese medicine composition and its preparation for treating breast cancer

Examples

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Comparison scheme
Effect test

Embodiment 1

[0015] Prescription: 30g yam, 25g tiankui (also known as red phoenix, above ground part), 20g lettuce, 15g astragalus, 10g safflower, 15g seaweed, 15g Chuanxiong, 15g calcined oyster, 10g licorice. The above raw materials are all dry products.

[0016] Preparation method: 1) Take Chinese yam and Tiankui, add 6 times the mass concentration of 0.35% NaOH aqueous solution to decoct and extract twice, each time for 2 hours, combine the extracts, concentrate to 1 / 3 volume, and use mass concentration Adjust the pH value of the 2% HCl solution to 7.0, extract twice with an equal volume of n-butanol, combine the n-butanol extracts, and dry up to obtain the preparation of yam chinensis; 2) take lettuce seeds, astragalus, seaweed, Ligusticum chuanxiong, safflower, calcined oyster, licorice, reflux extraction twice with 60% ethanol solution of 6 times the total weight, each time for 2 hours, combined extracts, dried to obtain the remaining drug preparation; The preparation is uniformly ...

Embodiment 2

[0019] Prescription: 30g yam, 25g tiankui (also known as red phoenix, above ground part), 20g lettuce, 15g astragalus, 10g safflower, 15g seaweed, 15g Chuanxiong, 15g calcined oyster, 10g licorice. The above raw materials are all dry products.

[0020] Preparation method: 1) Take Chinese yam and Tiankui, add 6 times the mass concentration of 0.45% NaOH aqueous solution to decoct and extract twice, each time for 2 hours, combine the extracts, concentrate to 1 / 3 volume, and use mass concentration Adjust the pH value of the 2% HCl solution to 7.0, extract twice with an equal volume of n-butanol, combine the n-butanol extracts, and dry up to obtain the preparation of yam chinensis; 2) take lettuce seeds, astragalus, seaweed, Ligusticum chuanxiong, safflower, calcined oyster, licorice, 60% ethanol solution of 60 times the total weight, reflux extraction twice, each time for 2 hours, combined extracts, dried to obtain the remaining drug preparation; The preparation is uniformly mix...

Embodiment 3

[0023] Prescription: 30g yam, 25g tiankui (also known as red phoenix, above ground part), 20g lettuce, 15g astragalus, 10g safflower, 15g seaweed, 15g Chuanxiong, 15g calcined oyster, 10g licorice. The above raw materials are all dry products.

[0024] Preparation method: 1) Take Chinese yam and Tiankui, add 6 times the mass concentration of 0.4% NaOH aqueous solution to decoct and extract twice, each time for 2 hours, combine the extracts, concentrate to 1 / 3 volume, and use mass concentration Adjust the pH value of the 2% HCl solution to 7.0, extract twice with an equal volume of n-butanol, combine the n-butanol extracts, and dry up to obtain the preparation of yam chinensis; 2) take lettuce seeds, astragalus, seaweed, Ligusticum chuanxiong, safflower, calcined oyster, licorice, reflux extraction twice with 60% ethanol solution of 6 times the total weight, each time for 2 hours, combined extracts, dried to obtain the remaining drug preparation; The preparation is uniformly m...

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Abstract

The invention belongs to the technical field of traditional Chinese medicine compound preparations, and in particular relates to a traditional Chinese medicine composition for treating breast cancer and its preparation. The traditional Chinese medicine composition comprises, in parts by mass of raw materials, 20-40 parts of yam, 20-25 parts of G. chinensis, 10-20 parts of lettuce seeds, 10-20 parts of astragalus, 10-20 parts of seaweed, 10-20 parts of Chuanxiong, 10-20 parts of calcined oyster, 10-20 parts of licorice. It uses yam as the monarch drug to nourish yin, lettuce seeds with tonic properties as the minister drug, genus chinensis to clear away heat, astragalus to replenish qi and regulate qi, safflower and chuanxiong to activate blood, seaweed and calcined oyster to soften and resolve stagnation. , to reconcile the various medicines with licorice. Compared with the prior art, the traditional Chinese medicine composition for treating breast cancer according to the present invention is aimed at the pathogenesis of breast cancer, and the prescription is more reasonable, and the scope of application is wider; moreover, it can avoid the carcinogenic effect of G. The role, and strengthen the anti-breast cancer effect of the whole party.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compound preparations, and in particular relates to a traditional Chinese medicine composition for treating breast cancer and its preparation. Background technique [0002] Breast cancer is a malignant tumor that seriously threatens women's health, accounting for the first place in the incidence of female tumors. The mammary gland is not an important organ to maintain human life activities, and breast cancer in situ is not fatal; but because breast cancer cells lose the characteristics of normal cells, the connections between cells are loose and easy to fall off. Once the cancer cells fall off, the free cancer cells can spread throughout the body with the blood or lymph fluid, forming metastasis, which is life-threatening. [0003] At present, our medical development level can not explain the pathogenesis of breast cancer very accurately, and can not fully explain the occurre...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8945A61P35/00A61K35/618
CPCA61K35/618A61K36/02A61K36/236A61K36/28A61K36/286A61K36/481A61K36/484A61K36/8945A61K2236/331A61K2236/333A61K2236/39A61K2236/55A61K2300/00
Inventor 郭晓玲贾留顺
Owner 郭晓玲