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Gel preparation for treating prostatitis and preparation method of gel preparation

A technology of gel preparation and prostatitis, which is applied in the field of medicine, can solve problems such as unreasonable formula, difficult natural barrier of prostate capsule, and influence on curative effect, achieve good compatibility and stability, avoid liver first-pass effect, and treat ideal effect

Inactive Publication Date: 2018-08-10
揭从能
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, traditional Chinese medicine treatment of prostatitis has achieved a certain therapeutic effect, but it is not ideal enough, and the effective rate is low. It is embodied in: 1. The traditional Chinese medicine preparations currently used are mainly oral decoctions, pills, tablets, and capsules. Poor, patients usually have difficulty persisting for a long time
In addition, oral drugs have a first-pass effect in the gastrointestinal tract, and it is difficult to pass through the natural barrier of the prostate capsule, and it is difficult to reach the lesion directly. Usually, the effective concentration at the lesion is low, and it is difficult to exert a greater therapeutic effect, which affects the curative effect
2. The formula is unreasonable
Prostatitis is often a complex etiological process. Most of the existing Chinese medicine formulas cannot take all the disease factors into consideration. It is difficult to have a drug that can cure the disease immediately, so the treatment time is longer.
Just because of these reasons, the clinical effect of existing traditional Chinese medicine for the treatment of prostatitis is not ideal.

Method used

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  • Gel preparation for treating prostatitis and preparation method of gel preparation
  • Gel preparation for treating prostatitis and preparation method of gel preparation
  • Gel preparation for treating prostatitis and preparation method of gel preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] The formulation of the gel preparation:

[0047] Chinese herbal extract 5 parts

[0048] Propylene glycol 5 parts

[0049] Carbomer 934 1 serving

[0050] 2 parts ethanol

[0051] 2 parts triethanolamine

[0052] Laurocaprazine 6 parts

[0053] 10 parts deionized water

[0054] Wherein, the formula of Chinese medicine extract is:

[0055] Bupleurum extract 2 parts

[0056] Coptis chinensis extract 2 parts

[0057] Qin bark extract 5 parts

[0058] Rehmannia glutinosa extract 5 parts

[0059] Licorice extract 10 parts

[0060] Angelica extract 2 parts

[0061] Bitter almond extract 5 parts

[0062] Preparation:

[0063] (1) Weigh the deionized water in parts by weight, add carbomer 934 to swell under the condition of stirring, then add propylene glycol and ethanol in parts by weight, and continue stirring until the carbomer is completely swollen to form A liquid;

[0064] (2) according to the formula of Chinese medicine extract, take by weighing each compon...

Embodiment 2

[0067] The formulation of the gel preparation:

[0068] Chinese herbal extract 25 parts

[0069] Propylene glycol 50 parts

[0070] Carbomer 934 5 servings

[0071] 10 parts ethanol

[0072] 20 parts triethanolamine

[0073] Laurocaprazine 40 parts

[0074] 50 parts of deionized water

[0075] Wherein, the formula of Chinese medicine extract is:

[0076] Bupleurum extract 20 parts

[0077] Coptis chinensis extract 20 parts

[0078] Qin bark extract 50 parts

[0079] Rehmannia glutinosa extract 50 parts

[0080] Licorice extract 100 parts

[0081] Angelica Extract 20 parts

[0082] Bitter almond extract 50 servings

[0083] Preparation:

[0084] (1) Weigh the deionized water in parts by weight, add carbomer 934 to swell under the condition of stirring, then add propylene glycol and ethanol in parts by weight, and continue stirring until the carbomer is completely swollen to form A liquid;

[0085] (2) according to the formula of Chinese medicine extract, take by w...

Embodiment 3

[0088] The formulation of the gel preparation:

[0089] Chinese herbal extract 7 parts

[0090] 7.5 parts of propylene glycol

[0091] Carbomer 940 1.2 parts

[0092] 2.5 parts of ethanol

[0093] 2.5 parts of triethanolamine

[0094] Menthol 8 parts

[0095] 15 parts of deionized water

[0096] Wherein, the formula of Chinese medicine extract is:

[0097] Bupleurum extract 11 parts

[0098] Coptis chinensis extract 11 parts

[0099] Qin bark extract 28 parts

[0100] Rehmannia glutinosa extract 25 parts

[0101] Licorice extract 55 parts

[0102] Angelica extract 10 parts

[0103] Bitter almond extract 27 servings

[0104] Preparation:

[0105] (1) Weigh the deionized water in parts by weight, add carbomer 940 to swell under the condition of stirring, then add propylene glycol and ethanol in parts by weight, and continue stirring until the carbomer is completely swollen to form A liquid;

[0106] (2) according to the formula of Chinese medicine extract, take by ...

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Abstract

The invention discloses a gel preparation for treating prostatitis. The gel preparation is characterized by being prepared from the following components in parts by weight: 5 to 25 parts of Chinese herb extract, 5 to 50 parts of propanediol, 1 to 5 parts of Carbomer, 2 to 10 parts of ethanol, 2 to 20 parts of triethanolamine, 6 to 40 parts of transdermal absorption accelerant, and 10 to 50 parts of deionized water, wherein the Chinese herb extract comprises radix bupleuri extract, rhizoma coptidis extract, cortex fraxini extract and radix rehmanniae praeparata extract. The invention also discloses a preparation method and application of the gel preparation for treating the prostatitis. The active ingredients of the gel preparation for treating the prostatitis reach a prostatitis focus in ashortest distance by virtue of a rectal administration way, the treatment effect is ideal, the use is convenient, the active ingredients are sourced from the natural Chinese herb extract and safe, nontoxic and free from side effect, and the gel preparation has a significant treatment effect for the symptoms such as frequent micturition, urgent urination, paruria, greasy urine and the like causedby the prostatitis.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a gel preparation for treating prostatitis and a preparation method thereof. Background technique [0002] Prostatitis is a common disease in urology, including chronic bacterial prostatitis and non-bacterial prostatitis, mainly manifested as frequent urination, urgency, abnormal urination, white urine, etc., the incidence rate is extremely high, nearly 50% of men will Suffering from prostatitis. Because the clinical symptoms of prostatitis are complex and diverse, and have a certain impact on male sexual function and reproductive function, it seriously hinders the patient's quality of life and causes the patient's spirit and body to be greatly tortured. According to the pathology and etiology of the patient, choosing symptom-removing treatment is the most effective and feasible method. [0003] The current methods of treating prostatitis mainly include: [0004] Oral antimicrobial dru...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K9/06A61K47/32A61P13/08
CPCA61K9/0031A61K9/06A61K36/232A61K36/233A61K36/484A61K36/63A61K36/718A61K36/736A61K36/804A61K47/32A61P13/08A61K2300/00
Inventor 揭从能
Owner 揭从能
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