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Traditional Chinese medicine preparation for degrading aflatoxin and preparation method thereof

A traditional Chinese medicine preparation and traditional Chinese medicine technology, applied in the direction of medical formula, medical preparations containing active ingredients, antibacterial drugs, etc., can solve the problems of food and feed nutrition loss, incomplete degradation, reversible reaction, etc., to ensure activity and improve Immunity, efficient degradation effect

Inactive Publication Date: 2018-09-11
SHANDONG PEANUT RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] In order to efficiently degrade aflatoxin and solve the shortcomings of previous methods for degrading aflatoxin, such as incomplete degradation, reversible reaction, and loss of nutrition in food and feed, the present invention provides a traditional Chinese medicine preparation for degrading aflatoxin and a preparation method thereof. The prepared traditional Chinese medicine preparation can completely degrade aflatoxin, and the degradation product is non-toxic and safe, and can increase the nutritional value of food and feed, and has the characteristics of high efficiency, safety and nutrition

Method used

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  • Traditional Chinese medicine preparation for degrading aflatoxin and preparation method thereof

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Effect test

Embodiment 1

[0044] In parts by weight, weigh 25 parts of Angelica dahurica, 20 parts of Pekoe, 15 parts of Baiying, 10 parts of Hedyotis diffusa, 10 parts of Lobelia, 8 parts of Alum, 7 parts of Radix Paeoniae Alba, 3 parts of Scutellaria barbata, and blood ginseng 2 parts, each Chinese medicine ingredient is subjected to high-speed disc shear ultrafine grinding and fluidized bed airflow collision ultrafine grinding respectively, and the crushing particle size is 600 to 800 mesh, and then the ingredients are mixed; the mixed Chinese medicine ingredients are divided into 1: 20 (weight to volume ratio (g:mL)) was added to water, mixed evenly and then subjected to microwave extraction. The conditions for microwave-assisted extraction of traditional Chinese medicine preparations were that the microwave power was 350W, the microwave temperature was 20°C, and the microwave time was 5min; To obtain filtrate 1, add water to the filter residue at 1:10 (weight to volume ratio (g:mL)), and carry out ...

Embodiment 2

[0048] In terms of parts by weight, weigh 15 parts of Angelica dahurica, 12 parts of Pekoe, 15 parts of Baiying, 15 parts of Hedyotis diffusa, 15 parts of Lobelia, 10 parts of Alum, 10 parts of Radix Paeoniae Alba, 5 parts of Banzhilian, blood ginseng 3 parts, each Chinese medicine ingredient is subjected to high-speed disc shearing ultrafine grinding and fluidized bed airflow collision ultrafine grinding respectively, and the crushing particle size is 600 to 800 mesh, and then the ingredients are mixed; the mixed Chinese medicine ingredients are divided into 1: 10 (weight-to-volume ratio (g:mL)) was added to water, mixed evenly, and subjected to microwave extraction. The conditions for microwave-assisted extraction of traditional Chinese medicine preparations were that the microwave power was 400W, the microwave temperature was 25°C, and the microwave time was 4min; To obtain filtrate 1, add water to the filter residue at a ratio of 1:7 (weight to volume ratio (g:mL)), and car...

Embodiment 3

[0051] In terms of parts by weight, weigh 10 parts of Angelica dahurica, 20 parts of Pekoe, 20 parts of Baiying, 12 parts of Hedyotis diffusa, 10 parts of Lobelia, 10 parts of Alum, 10 parts of Radix Paeoniae Alba, 5 parts of Banzhilian, blood ginseng 3 parts, each Chinese medicine ingredient is subjected to high-speed disc shearing ultrafine grinding and fluidized bed airflow collision ultrafine grinding respectively, and the crushing particle size is 600 to 800 mesh, and then the ingredients are mixed; the mixed Chinese medicine ingredients are divided into 1: 15 (weight-to-volume ratio (g:mL)) was added into water, mixed evenly, and then subjected to microwave extraction. The conditions for microwave-assisted extraction of traditional Chinese medicine preparations were that the microwave power was 450W, the microwave temperature was 30°C, and the microwave time was 5 minutes; , to obtain filtrate 1, the filter residue was added into water at 1:7 (weight to volume ratio (g:mL...

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Abstract

The invention discloses a traditional Chinese medicine preparation for degrading aflatoxin and a preparation method and application thereof, and belongs to the field of biological pollution and control. The traditional Chinese medicine preparation is prepared by microwave extraction of crushed Chinese herbal components. The Chinese herbal components comprise (by weight): 10-25 parts of dahurian angelica root, 10-20 parts of pekoe, 10-20 parts of Solanum dulcamara, 5-15 parts of heydyotis, 5-15 parts of radical lobelia, 5-10 parts of alum, 5-10 parts of white peony root, 3-5 parts of barbat skullcap and 1-3 parts of Wedelia wallichii Less. The traditional Chinese medicine preparation can fully degrade aflatoxin and also can degrade cyclopiazonic acid. Toxin groups are completely degraded and the reaction is irreversible. In addition, the prepared traditional Chinese medicine preparation also has health-care functions of invigorating blood circulation and beautifying the features, strengthening stomach and protecting liver, raising immunity, resisting bacteria, nourishing blood and invigorating energy and calming the nerves.

Description

technical field [0001] The invention belongs to the field of biological pollution and control, and in particular relates to a traditional Chinese medicine preparation for degrading aflatoxin and a preparation method thereof. Background technique [0002] Aflatoxins are a class of compounds with very similar chemical structures produced by fungi such as Aspergillus flavus and A. parasiticus. Aflatoxin is the most important mycotoxin that pollutes grain and oil crops, food and feed in my country and the world. It is highly toxic and carcinogenic, and seriously endangers the health of humans and animals. In 1993, aflatoxin B1 was listed as a class I carcinogen by the World Health Organization, and it is one of the strongest known carcinogens. [0003] Aflatoxin seriously pollutes food and feed agricultural products. Aflatoxins can contaminate grains such as corn, wheat, rice, sorghum, oil crops such as peanuts, sunflower seeds, soybeans, and cottonseeds, spices such as dried ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/82A61P1/00A61P1/14A61P1/16A61P7/00A61P7/06A61P17/00A61P25/20A61P31/04A61P37/04A23L5/20A23L33/105A23L5/30A61K33/06
CPCA23L5/27A23L5/34A23L33/105A23V2002/00A61K33/06A61K36/232A61K36/28A61K36/34A61K36/539A61K36/65A61K36/71A61K36/748A61K36/81A61K36/82A61K2236/331A61P1/00A61P1/14A61P1/16A61P7/00A61P7/06A61P17/00A61P25/20A61P31/04A61P37/04A61K2300/00A23V2200/318A23V2200/32A23V2200/324A23V2200/30A23V2250/21
Inventor 张初署孙杰于丽娜王明清毕洁张智猛赵善仓刘宾
Owner SHANDONG PEANUT RES INST
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