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Solution for extracting drugs in hair and application method thereof

An application method and hair technology, applied in the field of public safety detection, can solve the problems of complex process, long cycle, and limit the application scope of drugs in hair, and achieve the effect of expanding the application scope and shortening the detection cycle.

Pending Publication Date: 2018-12-25
徐多麒
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing hair drug detection technology only stays in the instrument detection in the laboratory. The commonly used instrument detection methods are gas chromatography-mass spectrometry, high performance liquid chromatography tandem mass spectrometry, etc. However, these detection methods are complicated in process and relatively short cycle time. Long, which limits the application range of drug detection in hair

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A solution for extracting drugs from hair, including a drug-releasing agent in hair for releasing drugs from hair and capable of dissolving both hair and drug targets, and capable of immunoreacting with colloidal gold Combined drug thinner in hair, the parts by weight of each component in its formula are as follows:

[0037] 0.9 parts of drug-releasing agent in hair;

[0038] 1 part drug thinner in hair.

[0039] Preferably, the drug releasing agent in hair is made by mixing methanol and ethanol at a weight ratio of 2:5.

[0040] Preferably, the drug diluent in hair is prepared by mixing deionized water, dithiothreitol and K proteinase in a weight ratio of 1:2:2.

[0041] A method for applying a solution for extracting drugs from hair, the specific steps are as follows:

[0042] Step 1, physically crushing the hair sample to obtain a hair sample powder;

[0043] Step 2: Weigh the drug-releasing agent in hair according to the ratio of 10ul per 1mg of hair sample, and...

Embodiment 2

[0049] A solution for extracting drugs from hair, including a drug-releasing agent in hair for releasing drugs from hair and capable of dissolving both hair and drug targets, and capable of immunoreacting with colloidal gold Combined drug thinner in hair, the parts by weight of each component in its formula are as follows:

[0050] 1 part drug release agent in hair;

[0051] 10 parts of drug thinner in hair.

[0052] Preferably, the drug releasing agent in hair is made by mixing methanol and ethanol at a weight ratio of 2:10.

[0053] Preferably, the drug diluent in hair is prepared by mixing deionized water, dithiothreitol and protein K in a weight ratio of 1:2:3.

[0054] A method for applying a solution for extracting drugs from hair, the specific steps are as follows:

[0055] Step 1, physically crushing the hair sample to obtain a hair sample powder;

[0056]Step 2: Weigh the drug-releasing agent in hair according to the ratio of 100 ul per 1 mg of hair sample, and mi...

Embodiment 3

[0062] A solution for extracting drugs from hair, including a drug-releasing agent in hair for releasing drugs from hair and capable of dissolving both hair and drug targets, and capable of immunoreacting with colloidal gold Combined drug thinner in hair, the parts by weight of each component in its formula are as follows:

[0063] 0.95 copies of drug-releasing agent in hair;

[0064] 3 parts drug thinner in hair.

[0065] Preferably, the drug releasing agent in hair is made by mixing methanol and ethanol at a weight ratio of 2:7.

[0066] Preferably, the drug diluent in hair is prepared by mixing deionized water, dithiothreitol and protein K in a weight ratio of 1:2:2.5.

[0067] A method for applying a solution for extracting drugs from hair, the specific steps are as follows:

[0068] Step 1, physically crushing the hair sample to obtain a hair sample powder;

[0069] Step 2: Weigh the drug-releasing agent in hair at a ratio of 50 ul per 1 mg of hair sample, and mix the...

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Abstract

The invention provides a solution for extracting drugs in hair and an application method thereof. The solution comprises a drug release agent in hair and a drug diluent in hair. The application methodcomprises the following steps: performing physical crushing on the hair sample to obtain hair sample powder; weighing the drug release agent in the hair according to the mass of the hair sample, andmixing and oscillating the hair sample with a drug release agent in the hair; weighing the drug diluent in the hair according to the mass of the drug release agent in the hair, and mixing and oscillating the diluent with the drug release mixed solution in the hair; and finally, using a colloidal gold detection box to detect the drug diluting mixed solution in hair. The drug release agent and the diluent in hair used in the invention can quickly release and dissolve the drugs in hair, and are suitable for the colloidal gold detection box. With the method, the detection period of drugs in hairis shortened, the application range of drug detection in hair is expanded, and the public safety department and the judicial department can apply the solution for extracting drugs in hair to the drugaddiction sites of public places such as airports, stations and the like.

Description

technical field [0001] The invention relates to the technical field of public safety detection, in particular to a solution for extracting drugs from hair and an application method thereof. Background technique [0002] At present, cases of robbery, theft, violence, and traffic accidents caused by drug abuse are increasing all over the world, seriously affecting social security and public safety. Against the backdrop of the globalization of the drug problem, China's drug situation remains severe and complex. In the "Decision on Amending the Measures for the Identification of Drug Addiction" implemented since April 1, 2017, the detection of drug components in human hair samples is an important basis for public security organs to identify drug addiction. Compared with other test materials, hair analysis can avoid the interference of temporary drug cutting or adulteration, easy sampling, stable test materials, reliable results, and a wide detection period, which can reflect th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/558G01N1/28G01N1/38G01N1/42
CPCG01N1/28G01N1/286G01N1/38G01N1/42G01N33/558
Inventor 徐多麒
Owner 徐多麒
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