Acid permeation high-pressure freezing wall breaking technology for Ganoderma lucidum spore

A technology of Ganoderma lucidum spore powder and wall-breaking Ganoderma lucidum spore powder is applied in the field of Ganoderma lucidum spore powder breaking, which can solve the problems of complex equipment, large investment, and unfavorable preservation of effective components of Ganoderma lucidum spores.

Inactive Publication Date: 2019-01-08
广东润源中天生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The working principles of the physical method are different, and the advantages and disadvantages are also different. Generally speaking, the physical method consumes a lot of energy, and the equipment is more complicated and the investment is larger.
(4) Mechanical method: This method includes the "rolling and extrusion method" of breaking the wall of Ganoderma lucidum spores by rapidly swinging, grinding, and squeezing the tank and ball mill under low temperature and other conditions. The unbroken Ganoderma lucidum spores are maintained in a high-pressure state, and then released to a lower pressure at another time, so that the pores on the cell wall of the Ganoderma lucidum spores are enlarged and increased, and the compressed air Enter the grinding chamber through the grinding nozzle at a specific angle to generate a high-speed spiral airflow. The material rotates at a high speed in the grinding chamber under the drive of the spiral airflow, and the particles collide with each other due to different speeds, so as to achieve the effect of crushing. "And the "high-pressure homogenization method" that uses the impact, shearing, cavitation, turbulence, etc. of the high-pressure homogenizer to grind the material into tiny particles to achieve the effect of homogenization; the advantage of the mechanical method is that it is simple to operate, Easy to operate, the disadvantage is that the investment in mechanical equipment is large and the operating cost is high
But at present, all these wall-breaking methods destroy the spore wall of the ganoderma spores, exposing the contents of the ganoderma spores, which can easily cause oxidative deterioration of the contents, which is very unfavorable for the preservation of the active ingredients of the ganoderma spores

Method used

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  • Acid permeation high-pressure freezing wall breaking technology for Ganoderma lucidum spore
  • Acid permeation high-pressure freezing wall breaking technology for Ganoderma lucidum spore
  • Acid permeation high-pressure freezing wall breaking technology for Ganoderma lucidum spore

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0006] Take the unbroken Ganoderma lucidum spore powder and divide it into three experimental groups, each of 40 grams, No. 1 is the unbroken Ganoderma spore powder control, and the No. 2 unbroken Ganoderma lucidum spore powder + 65ml of 1% hydrochloric acid infiltration experimental group. No. 3 unbroken Ganoderma lucidum spore powder + 65ml 3% acetic acid soaking experiment group, No. 1 without acid soaking, No. 2 and No. 3 with acid soaking for 1 hour, put it in a pressure cooker and high pressure, heat up, and heat up to 25 minutes At 121°C, keep 121°C for 30 minutes, cool down, 2.5 hours to 65°C, take it out, put it in a 65°C oven for 6 hours, then place it in a 4°C refrigerator for 12 hours, take it out, and then bake at 65°C Dry for 1 hour, weigh, and get ready.

[0007] See Table 1 for the weight change of the sample after high pressure drying.

[0008] Table 1 Dry weight change of Ganoderma lucidum spore powder after high pressure

[0009]

[0010] Note: 1 is the control o...

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Abstract

The invention discloses an acid permeation high-pressure freezing wall breaking technology for Ganoderma lucidum spore. Through the scheme, Ganoderma lucidum spore is firstly permeated and soaked withacid, and then through high pressure wall breaking and freezing wall breaking, the Ganoderma lucidum spore can be completely broken, and the content of the Ganoderma lucidum spore is completely released. Specifically, the Ganoderma lucidum spore without wall breaking is permeated and soaked with acid, sterilization high pressure wall breaking is carried out, the Ganoderma lucidum spore is dried inside an oven at the temperature of 65 DEG C, then is frozen inside a refrigerator at the temperature of 4 DEG C, and then is dried inside an oven at the temperature of 65 DEG C so as to complete thewall braking function of the Ganoderma lucidum spore. The wall braking rate of the high pressure freezing wall breaking method can reach more than 99%, wherein the content of the main effective ingredient ganoderan of the Ganoderma lucidum spore is 2.5 to 3.5 times of that before wall breaking, and is 1.5 to 2.0 times of the content of the wall-broken Ganoderma lucidum spore in a traditional wallbreaking technology. Moreover, the wall breaking technology accords with the sanitary condition, the content of the Ganoderma lucidum spore is not exposed, the oxidative deterioration of the content is unlikely to cause, the product can be directly filled into capsules or crushed into tablets, and the Ganoderma lucidum spore also can be stored for a long time in the condition without contamination.

Description

Technical field [0001] The invention belongs to the technical field of Ganoderma lucidum spore powder wall breaking technology, and specifically relates to a method for acid osmosis and high-pressure freezing wall breaking of Ganoderma lucidum spore powder and a production process thereof. Background technique [0002] Ganoderma is a kind of medicinal fungus plant belonging to the genus Ganoderma of the Basidiomycete Polyporaceae. Ganoderma lucidum spores are very tiny spores ejected from the cap when Ganoderma lucidum matures. 8.5~11.2μm×5.2~6.9μm, with double wall structure. The chemical composition of Ganoderma lucidum spores mainly includes the following categories: proteins and amino acids, glycopeptides, vitamins, carotenes, sterols, triterpenes, alkaloids, fatty acids, lactones and inorganic ions. Ganoderma lucidum spores are rich in polysaccharides and oligosaccharides, but due to its tough double-walled structure, the active ingredients in the spores are difficult to re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/074C12N1/06
CPCA61K36/074C12N1/06A61K2236/17A61K2236/15
Inventor 吴铁唐林志吕思敏杨惠华杨崇胜何小冰丁鸿燕
Owner 广东润源中天生物科技有限公司
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