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Application of high-pressure and freezing wall breaking method in production process of preparing wall-broken ganoderma lucidum spore powder

A broken ganoderma lucidum spore powder and production process technology, applied in the direction of microorganism dissolution, microorganisms, methods based on microorganisms, etc., can solve the problems of large energy consumption, large investment, and large investment in mechanical equipment in physical methods

Inactive Publication Date: 2019-01-08
广东润源中天生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The working principles of the physical method are different, and the advantages and disadvantages are also different. Generally speaking, the physical method consumes a lot of energy, and the equipment is more complicated and the investment is larger.
(4) Mechanical method: This method includes the "rolling and extrusion method" of breaking the wall of Ganoderma lucidum spores by rapidly swinging, grinding, and squeezing the tank and ball mill under low temperature and other conditions. The unbroken Ganoderma lucidum spores are maintained in a high-pressure state, and then released to a lower pressure at another time, so that the pores on the cell wall of the Ganoderma lucidum spores are enlarged and increased, and the compressed air Enter the grinding chamber through the grinding nozzle at a specific angle to generate a high-speed spiral airflow. The material rotates at a high speed in the grinding chamber under the drive of the spiral airflow, and the particles collide with each other due to different speeds, so as to achieve the effect of crushing. "And the "high-pressure homogenization method" that uses the impact, shearing, cavitation, turbulence, etc. of the high-pressure homogenizer to grind the material into tiny particles to achieve the effect of homogenization; the advantage of the mechanical method is that it is simple to operate, Easy to operate, the disadvantage is that the investment in mechanical equipment is large and the operating cost is high
But at present, all these wall-breaking methods destroy the spore wall of the ganoderma spores, exposing the contents of the ganoderma spores, which can easily cause oxidative deterioration of the contents, which is very unfavorable for the preservation of the active ingredients of the ganoderma spores

Method used

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  • Application of high-pressure and freezing wall breaking method in production process of preparing wall-broken ganoderma lucidum spore powder
  • Application of high-pressure and freezing wall breaking method in production process of preparing wall-broken ganoderma lucidum spore powder
  • Application of high-pressure and freezing wall breaking method in production process of preparing wall-broken ganoderma lucidum spore powder

Examples

Experimental program
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Effect test

Embodiment 1

[0006] Take unbroken Ganoderma lucidum spore powder and divide it into two experimental groups, 40 grams in each group. No. 1 is the unbroken Ganoderma lucidum spore powder as a control, and No. 2 unbroken Ganoderma lucidum spore powder is added with 65ml of purified water and put into a pressure cooker under high pressure. Heating up to 121°C in 25 minutes, keeping at 121°C for 30 minutes, cooling down to 65°C in 2.5 hours, taking it out, drying in a 65°C oven for 4 hours, then storing in a 4°C refrigerator for 12 hours, taking it out Crush it with a spoon, dry it at 65°C for 6 hours, weigh it, and get it.

[0007] See Table 1 for the weight change of samples dried under high pressure.

[0008] Table 1 Dry weight change of Ganoderma lucidum spore powder after high pressure

[0009]

[0010] Note: No. 1 is the control of Ganoderma lucidum spore dry powder without water; No. 2 is the control of Ganoderma lucidum spore powder with water.

[0011] See Table 2 for the dry wei...

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Abstract

The invention discloses a technical scheme of high-pressure and freezing wall breaking of ganoderma lucidum spore powder. In the scheme, high-pressure wall breaking and freezing wall breaking are combined to build a high-pressure and freezing wall breaking technology. The technical scheme adopts an excessive sterilization method for preparing an injection, namely, the technical scheme comprises the following steps: carrying out high-pressure wall breaking on ganoderma lucidum spores by adopting a 30-minute high-pressure sterilization method at 121 DEG C, then baking the ganoderma lucidum spores in a baking oven with a temperature of 65 DEG C, putting the ganoderma lucidum spores into a refrigerator for freezing at 4 DEG C for 12 to 24 h, taking out the ganoderma lucidum spores, and dryingthe ganoderma lucidum spores at 65 DEG C for 6 to 8 h, thus completing the wall breaking function of the ganoderma lucidum spores. The wall breaking rate of the high-pressure and freezing wall breaking method can reach up to 999 percent or above; the content of ganodermapolysaccharide, an main effective component, of the ganoderma lucidum spores is 1.97 to 2.19 times the content before wall breaking and is 1.45 to 1.79 times the content of the ganoderma lucidum spore powder subjected to wall breaking with a conventional wall breaking process. The wall breaking process meets a sanitary condition; inclusions of the ganoderma lucidum spores are not exposed, so that the possibility of oxidative deterioration of the inclusions is less, and the ganoderma lucidum spore powder can be preserved fora relatively long time. The product can be directly packaged into capsules or pressed into tablets.

Description

technical field [0001] The invention belongs to the technical field of ganoderma spore powder wall breaking, and in particular relates to a high-pressure freezing wall breaking method of ganoderma spore powder and a production process thereof. Background technique [0002] Ganoderma lucidum belongs to a medicinal fungal plant belonging to the genus Ganoderma lucidum of the family Polyporaceae. Ganoderma lucidum spores are extremely tiny spores ejected from the cap of Ganoderma lucidum when it matures. It has high medicinal value and pharmacological activity, including anti Cancer, immune regulation, anti-oxidation, neuroprotection, hepatoprotection and anti-diabetes and other pharmacological effects. Because Ganoderma lucidum spores have double-layer cell walls, which are mainly chitin, cellulose, lignin, etc., the cell walls are tough and difficult to crack, making it difficult for the active ingredients to be absorbed and utilized by the human body. There are mainly five ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/074C12N1/06C12R1/645
CPCA61K36/074C12N1/066
Inventor 吴铁唐林志吕思敏杨惠华杨崇胜何小冰丁鸿燕
Owner 广东润源中天生物科技有限公司
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