239 results about "Hepatoprotection" patented technology

The invention discloses health products or drug combinations and preparation techniques and quality detection methods with functions of strengthening the stomach, nourishing the liver and improving the memory. The health products or drug combinations are composed of root kudzuvine, haw, malt, mum, mulberry leaf and lotus leaf. During preparing the health products or drug combinations, different components are processed by distillating, filtering, immersing, decocting, condensing, decompressing to make the effectine drug ingredients into full play. The invention also provides quality control methods for components identification and assay of the health products or drug combinations. The health products or drug combinations have functions of strengthening the stomach, nourishing the liver and improving the memory.

The invention discloses active dendrobe polysaccharide capable of protecting liver and resisting liver fibrosis, whose chemical structural formula is seen in the figure. The active dendrobe polysaccharide is gala glucomannan taking glucose and mannose as a main chain and galactose as a branch, the molecular weight of the gala glucomannan is about 2.2*104dalton, and the mole ratio of glucose to mannose to galactose in the composition is 31:10:8. The invention further discloses extraction, separation and purification methods of the active dendrobe polysaccharide as well as the preparation method of antibody affinity chromatography of the active dendrobe polysaccharide. The active dendrobe polysaccharide prepared by the method has remarkable physiological activity of protecting liver and resisting liver fibrosis and can be used for preparing liver-protecting health care products and medicines for curing liver fibrosis.

The invention provides an anti-intoxication, alcohol-expelling and liver-protection preparation which has the functions of anti-intoxication, alcohol-expelling and auxiliary protection on alcoholic liver injury. The preparation consists of the following raw materials: 20-50 parts of vine tea, 5-15 parts of galangal, 10-40 parts of mung beans and 10-40 parts of poria cocos. The vine tea contains a great amount of flavonoid substances, and the dihydromyricetin in the vine tea has special effects in removing toxicity in alcohol, preventing alcoholic liver and fatty liver, inhibiting liver cell deteriorate, reducing the morbidity of liver cancer and protecting the liver. The galangal is acrid and hot in property, can enter the spleen and stomach channels, has the functions of eliminating cold to stop pain and warming the middle energy and stopping throwing and has a certain alcohol-expelling function, and moreover the flavonoid substance galangin in the galangal has a protection function on acute alcoholic liver injury. The poria cocos has the effects of clearing damp and promoting dieresis, tonifying spleen and quieting the heart, can promote the alcohol in bodies to discharge out along with urine, and is beneficial to sobering up. The mung beans have the effect of clearing away heat and toxic materials, can effectively relieve the symptoms of dizziness and unclear speaking after drinking alcohol, and furthermore has the pharmacologic action of protecting the liver and the kidney.

The invention discloses a moxa stick for improving brain health, which is characterized by comprising the following raw medicinal materials in parts by weight: 200 parts of folium artemisiae argyi, 1-5 parts of eaglewood, 5-15 parts of polygonum multiflorum, 1-5 parts of mulberry, 5-15 parts of dogwood, 10-20 parts of liquorice, 5-15 parts of sealwort, 4-8 parts of the bark of eucommia, and 4-8 parts of spina date seed. The invention further discloses a preparation method of the moxa stick. Because of being prepared by adding medicinal materials into folium artemisiae argyi, the moxa stick disclosed by the invention is safe, nontoxic and convenient to use, has the effects of stimulating the menstrual flow, activating collaterals, restoring consciousness, enlightening, reinforcing kidney, protecting liver, reducing internal heat and dispelling depression, is capable of improving brain health and preventing and treating brain diseases, and has good effects on a series of diseases caused by insufficient cerebral blood supply, such as cerebral infarction, cerebral arteriosclerosis, insufficient cerebral blood supply, infantile autism, depression and encephalatrophy; meanwhile, the moxa stick for improving brain health, which is disclosed by the invention, is capable of relieving emotion of people, reducing stress and improving sleep and has the obvious effect on psychiatric problems caused by tension and stress, such as schizophrenia.

The invention discloses a health product for protecting liver and a preparation method thereof. The health product for protecting liver is prepared from the following raw materials of: by weight, 1-5 parts of Dendrobium candidum, 3-8 parts of American ginseng and 12-20 parts of root of kudzu vine. It shows through pharmacological experiments that the health product provided by the invention has good effects of protecting liver, effectively raising liver function and promoting hepatocyte restoration and regeneration, has low adverse reactions, and is safe to take. According to the preparation method, the best preparation technology is determined according to physical and chemical property optimization of effective components of each raw material. The preparation method has strong operationality and is suitable for industrial production.

The invention relates to the application of a compound to treating hepatitis and aims at providing an isochlorogenic acid compound which has stronger effects of anti-HBV, anti-inflammation and liver protection, and has wide and rich sources, and simple and convenient extraction process. The technical proposal is as follows: the isochlorogenic acid compound is made from one or more than one of isochlorogenic acid A, isochlorogenic acid B and isochlorogenic acid C according to any mixture ratio; in addition, the technical proposal further comprises the application of the compound to preparing drugs for resisting hepatitis B virus, and resisting inflammation and protecting liver.

The invention discloses a hepatoprotectivespace Lactobacillus plantarum FH-SS18--86365L and an application thereof. The preservation number of the Lactobacillus plantarum FH-SS18--86365L is No. CGMCCNo. 16124. The invention also protects the plant Lactobacillus SS18-86365L is a bacterial agent of active ingredient. The invention also protects Lactobacillus plantarum SS18-86365L or that use of themicrobial agent in the preparation of the product. The use of the product is for the treatment and/or prevention of fatty liver. The use of the product is to treat and/or prevent hyperlipidemia. Theuse of the product is to protect the liver. The Lactobacillus plantarum SS18-86365L has that effect of protecting live and inhibiting the formation of fatty liver, and has wide market application prospect.

The invention discloses new medical application of glycyrrhiza inflata ethanol extract and licochalcone A. The inventor discovers that glycyrrhiza inflata and other medical licorice root have obvious chemical ingredient difference, furthermore systematically researches the glycyrrhiza inflata ethanol extract and the important ingredient licochalcone A therein, and discovers that the glycyrrhiza inflata ethanol extract and the licochalcone A have remarkable activity in protecting oxidized cell injury, tissue injury and acute chemical liver injury. Based on the discovery, the extract and an active compound or pharmaceutically acceptable salt, ester and a solvate, a stereoisomer, tautomer, a prodrug and a mixture thereof can be used for preparing medicaments and health products for treating/preventing oxidative injury and/or acute chemical liver injury.

The invention discloses an olive total phenylethanoid glycoside composition. The olive total phenylethanoid glycoside composition comprises 6 types of particular phenylethanoid glycoside compositions which include cistanoside E, calcelarioside B, verbascoside, isoverbascoside, forsythoside B and alyssonoside and are varied from a general formula A. Pathological tests show that the olive total phenylethanoid glycoside composition in the general formula A has good anti-liver fibrosis and liver protection effects, can be used as an active ingredient of medicines for resisting liver diseases, canbe independently used or combined with proper excipients and the like, and is prepared into oral or non-oral dosage forms by conventional methods to be used for preparing medicines for treating liverdiseases.

The invention relates to the technical field of medicines. Chalcone is a natural component in plants and has antibiotic and antifungal effects, and derivatives of the chalcone also have the effect of resisting tumors and the like. At present, no document is reported that the derivatives of the chalcone have the effect of reducing activity of blood fat and protecting the liver. The invention provides derivatives of the dihydrochalcone having a general formula I. Through tests of reducing blood fat, the results show that the derivatives of the dihydrochalcone have the effects of obviously reducing serum total cholesterol and low-density lipoprotein cholesterol, and can be used to prepare medicines or health products for reducing blood fat, preventing and treating hyperlipoidemia, fatty liver, hepatocirrhosis and atherosclerosis and protecting the liver.

The invention relates to a method for the treatment or prevention of diseases or conditions associated with vascular endothelium dysfunction or liver injury comprising the administration to a patient in a need of such treatment or prevention of a therapeutically or prophylactically effective amount of a compound selected from the group consisting of:

wherein R represents hydrogen atom, CH₃, OH, pyridyl (C₅H₄N), 1-methylpyridyl (C₅H₄N—CH₃) or pyridyl substituted with hydroxy group ((OH)C₅H₃N), and X represents a physiologically acceptable counterion.

The invention relates to a novel compound, pharmaceutical compositions thereof as well as preparation methods thereof and use of the novel compound and the pharmaceutical compositions, and belongs to the field of pharmacy. The novel compound is oleanolic acid amino glucoside and pharmaceutically acceptable salts. A physical and chemical constant test displays that the solubility of the novel compound is enhanced by tens to hundreds of times in comparison with that of the oleanolic acid. An experiment verifies that the novel compound and the pharmaceutical compositions have more excellent effects than the oleanolic acid in the aspects such as blood pressure reduction, tumor resistance, liver protection and reduction of blood fat.

The present invention relates to a pharmaceutical composition useful as a hepatoprotective agent, said composition comprising of a mixture of coumarinolignoids of formula 1,2 and 3. The present invention also relates to a improved process for production of liver protective composition containing coumarinolignoids of formula 1, 2 and 3 from Cleome viscosa with optimized ratios of the same. More particularly, the present invention relates to a processing technology for the isolation of a combination of coumarinolignoids Cliv-92 comprising a mixture of coumarinolignoids of formula 1,2 and 3 from the seeds of Cleome viscosa.

The invention relates to the extracting technics of the amylase of the privet and the astragalus and the production and the appliance. The amylose is gained from the extracting and retreated the active ingredient amylose of the privet and the astragalus root; the extracting technics is easy and reasonable; the cost is cheap; the gained production is tested to be the glossy privet fruit amylose and the astagalus root amylose; the production has the function of boosting up the body immunologic function and boosting the cell metabolize, regulating the composing of the rna, the deoxyribonucleic acid and the albuminoid, reinforcing the kidney and nourishing the liver; at the same time , it has other function of the antivirus, resisting the knub, fighting against senium, resisting the radiste, resisting the stress, the oxidation resisting ; it can be use to improved the body immunologic function and protect the function of the marrow and the adrenocrtication and cure the disease due to asthenia of viscera and cooperate the operation, radistion therapy, the chemic therapy and accelerate the resume of the positive function and the prevention and treatment of the hepatitis, the diabetes, the flu, the cerebral thrombosis clinically.

The invention provides application of a compound shown in a general formula I in preparing a hepatic or health-care food. The invention also provides a pharmaceutical composition containing the compound shown in the general formula I. The medicament belongs to a pure natural preparation, is safe and reliable, is developed from food, has small toxicity, and has no adverse reaction after being usedfor a long time; the medicament can be drunk as tea, and has convenient use and delicious taste; the medicament has protection effect on hepatic injury caused by various reasons, and has prevention and treatment effects on various diseases caused by the hepatic injury; and the medicament has good effect on treating or preventing acute alcoholism, and can obviously improve various symptoms caused by alcoholic intoxication such as dizziness, headache, hypodynamia and the like.

The invention discloses new application of phillyrin, phillyrin derivatives, and a phillyrin-phillygenin composition in preparation of drugs or health products for liver protection, liver care and liver injury resistance. Tests prove that the phillyrin, phillyrin derivatives, and phillyrin-phillygenin composition have the characteristics of significant liver protection, liver care and liver injury resistance effect, quick effect and small toxic and side effect, are a safe, efficient and stable liver protection and liver injury resistance drug with a simple preparation process, and are suitable for industrial production and easy for popularization. The invention provides a new drug source for liver protection and liver injury resistance.

At least one isolated lactic acid bacteria strains selected from the following: TSP05 (Lactobacillus plantarum), TSF331 (Lactobacillus fermentum) and TSR332 (Lactobacillus reuteri) is provided. The above-mentioned active or inactive lactic acid bacteria strains have a function of hepatoprotection and is used in a form of a food composition or a pharmaceutical composition.

The invention discloses an extract with the functions of inflammation prevention and liver protection, which is prepared from propolis through a great deal of process research. Strict activity experiment shows that the extract has the inhibiting effect on human leukocyte elastase and has the protection effect on liver injury caused by carbon tetrachloride. The extract can be applied to development of plant source inflammation prevention and liver protection products. At present, the propolis is utilized primitively in China. As a raw material for producing plant source inflammation prevention and liver protection products, the propolis extract which is disclosed by the invention has the advantages of high eating security and simple process. A tablet prepared from the propolis extract is simple in prescription and preparation method, stable in quality and beneficial to popularization and application.

The invention relates to the field of pharmacy, and discloses a pharmaceutical composition for treating flu or hyperpyrexia caused by bacterial virus. The pharmaceutical composition is composed of 1 part of astragalus polysaccharides by weight, 2-3 parts of baicalin by weight and 2-3 parts of diclofenac sodium by weight, and can be prepared with pharmaceutically acceptable carriers according to the conventional methods of pharmaceutical preparations to obtain various dosage forms such as powder, granules, tablets, oral liquid or injection and the like suitable for application for patients. The pharmaceutical composition for treating flu or hyperpyrexia caused by bacterial virus has the advantages of treatment of both principal and secondary aspects of disease, good curative effect, quick effect-taking speed and the like, and the actions of the astragalus polysaccharides and the baicalin on protecting the liver and promoting urination can alleviate the side effects of the diclofenac sodium such as gastrointestinal reaction, hepatorenal damage and the like, and also can reduce the occurrence of delay of diseases because the strong abirritation of the diclofenac sodium covers up the clinical symptoms of inflammation, ulcer and the like.

Dibenzo quinolizine compound entity has relatively low hygroscopicity and relatively high storage stability, and is applicable to preparation of analgesic, sedative, hypnotic and tranquillizing medicines, medicines for treating hypertension, arrhythmia and functional dyspepsia, stopping cough, resisting schizophrenia and heroin and other drug dependence, reversing tumor cell drug resistance and delaying or reducing myocardial ischemia reperfusion injury, calcium antagonists, and medicines for protecting the liver and preventing visceral implicated reaction and other effects, which are applied to humans or animals.