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A kind of purposes of benzofuran derivative

A technology of benzofuran and derivatives, which is applied in the field of organic benzofuran derivatives, can solve the problems of high toxicity of borax, multi-organ accumulation poisoning, slow curative effect, etc., and achieve the purpose of regulating the oral environment, invigorating the spirit, and eliminating fatigue Effect

Active Publication Date: 2021-02-02
广州新致信息科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, borax is highly toxic and is a banned product for food additives in various countries in the world. If the human body takes too much boron, it will cause cumulative poisoning of multiple organs. Therefore, it is urgent to develop a toothpaste with less toxicity. need
[0004] Chinese patent application CN108056988A discloses an anti-inflammatory toothpaste. The anti-inflammatory ingredients of this toothpaste use peppermint oil, paeonol, marigold, honeysuckle, and dandelion. At the same time, ingredients for whitening teeth are added, which has dual effects of whitening and anti-inflammatory. However, this toothpaste uses important ingredients for anti-inflammatory , the curative effect is slow, long-term use is required to achieve a complete anti-inflammatory effect

Method used

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  • A kind of purposes of benzofuran derivative
  • A kind of purposes of benzofuran derivative
  • A kind of purposes of benzofuran derivative

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1, a kind of bactericidal and anti-inflammatory toothpaste

[0032] The bactericidal and anti-inflammatory toothpaste consists of the following components and their mass percentages:

[0033] Moisturizing agent 15%, flavoring agent 0.6%, foaming agent 1.3%, friction agent 20%, thickener 0.1%, bacteriostat 1%, deionized water 62%; Described bacteriostasis consists of honeysuckle essential oil and formula I The benzofuran derivatives are composed in a mass ratio of 7:3.

[0034] The moisturizing agent is composed of propylene glycol and sorbitol in a mass ratio of 5:2; the flavoring agent is composed of lemon essential oil and eugenol in a mass ratio of 4:1; the foaming agent is sodium lauryl sulfate; the The friction agent is calcium carbonate powder; the thickener is hydroxyethyl cellulose.

[0035] The preparation method of described bactericidal and anti-inflammatory toothpaste, comprises the steps:

[0036] S1, dissolving humectant, foaming agent, frict...

Embodiment 2

[0040] Embodiment 2, a kind of bactericidal and anti-inflammatory toothpaste

[0041] The bactericidal and anti-inflammatory toothpaste comprises the following components and their weight percentages:

[0042] Moisturizing agent 30%, flavoring agent 1%, foaming agent 2.0%, friction agent 40%, thickener 1%, bacteriostat 3%, deionized water 23%; Described bacteriostasis consists of honeysuckle essential oil and formula I The benzofuran derivatives are composed in a mass ratio of 7:6.

[0043] The moisturizing agent is composed of propylene glycol and sorbitol in a mass ratio of 5:4; the flavoring agent is composed of lemon essential oil and eugenol in a mass ratio of 4:3; the foaming agent is sodium lauryl sulfate; the The friction agent is calcium carbonate powder; the thickener is hydroxyethyl cellulose.

[0044] The preparation method of described bactericidal and anti-inflammatory toothpaste, comprises the steps:

[0045] S1, dissolving humectant, foaming agent, friction ...

Embodiment 3

[0049] Embodiment 3, a kind of bactericidal and anti-inflammatory toothpaste

[0050] The bactericidal and anti-inflammatory toothpaste comprises the following components and their weight percentages:

[0051] Moisturizing agent 22%, flavoring agent 0.8%, whipping agent 1.7%, friction agent 27%, thickener 0.7%, bacteriostat 2.8%, deionized water 45%; Described bacteriostasis consists of honeysuckle essential oil and formula I The benzofuran derivatives are composed in a mass ratio of 7:5.

[0052] The moisturizing agent is composed of propylene glycol and sorbitol in a mass ratio of 5:3; the flavoring agent is composed of lemon essential oil and eugenol in a mass ratio of 2:1; the foaming agent is sodium lauryl sulfate; the The friction agent is calcium carbonate powder; the thickener is hydroxyethyl cellulose.

[0053] The preparation method of described bactericidal and anti-inflammatory toothpaste, comprises the steps:

[0054] S1, dissolving humectant, foaming agent, fr...

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Abstract

The invention belongs to the field of use of organic benzofuran derivatives, and in particular relates to a use of benzofuran derivatives. The benzofuran derivatives of formula I provided by the present invention are used to prepare bactericidal and anti-inflammatory daily necessities, and the benzofuran derivatives are applied to the use of bactericidal and anti-inflammatory toothpaste, and the bactericidal and anti-inflammatory toothpaste has significant antibacterial and anti-inflammatory properties , Prevent gum bleeding, improve oral environment and analgesic effect, and do not add any hormone drugs at the same time, it has the advantages of high safety and low side effects.

Description

technical field [0001] The invention belongs to the field of use of organic benzofuran derivatives, and in particular relates to a use of benzofuran derivatives. Background technique [0002] Toothpaste is a cleaning product commonly used in daily life and has a long history. With the continuous development of science and technology, the continuous improvement and perfection of process equipment, various types of toothpaste have come out one after another, mainly including common cleaning toothpaste and bactericidal and anti-inflammatory toothpaste at present. And along with the continuous improvement of people's living standards, tooth decay and dental inflammation diseases are particularly common, therefore, antibacterial and anti-inflammatory toothpaste has become the mainstream of research. [0003] Chinese patent application CN102871881A discloses an anti-inflammatory toothpaste, which adds anti-inflammatory ingredients clove basil oil, borax and ginger oil to the acti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/343A61K8/92A61K8/49A61K8/34A61P1/02A61P31/02A61P31/04A61Q11/00A61P29/00
CPCA61K8/347A61K8/4973A61K8/922A61K31/343A61K2800/592A61Q11/00A61P1/02A61P29/00A61P31/02A61P31/04
Inventor 曹华郭鹏峰王恩明
Owner 广州新致信息科技有限公司
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