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265results about How to "Long-term protection" patented technology

Silane/graphene oxide composite passivation liquid and preparing method and application thereof

The invention relates to silane / graphene oxide composite passivation liquid and a preparing method and application thereof. The preparing method comprises the following steps that a water-based silanecoupling agent, water and alcohol are mixed according to the volume ratio being 1:(7-9):(0.8-1.2) to obtain mixing liquid; graphene oxide is added into the mixing liquid, and ultrasonic treatment iscarried out to obtain dispersion liquid; the pH value of the dispersion liquid is adjusted to be 2-4, and hydrolysis is carried out to obtain the silane / graphene oxide composite passivation liquid. The silane / graphene oxide composite passivation liquid and the preparing method of the silane / graphene oxide composite passivation liquid combine advantages of the graphene oxide and silane, the graphene oxide and the water-based silane coupling agent are used for joint hydrolysis, and the silane functionalization of the graphene oxide is achieved; and the silane coupling agent and a metal substrateform covalent bonds, the bonding force between a film layer and the metal substrate is improved, and the lamellar graphene oxide can strengthen the physic shielding property of the film layer on a corrosion medium.
Owner:GUANGZHOU SPECIAL PRESSURE EQUIP INSPECTION & RES INST

Long-acting sustained release preparation for preventing or treating retinal damage, and preparation method thereof

ActiveCN102233129ARelieve painSolve the problem of long-term frequent injectionsSenses disorderPeptide/protein ingredientsMicrosphereRetinal ganglion
The invention belongs to the field of pharmaceutical preparations, and relates to a long-acting sustained release preparation for preventing or treating retinal damage, and a preparation method thereof. The long-acting sustained release preparation takes erythropoietin (EPO) as an active component, takes dextran as a protective agent for the active component, and takes poly(lactic-co-glycolic acid), polylactic acid or polycaprolactone as a coating component to prepare sustained release microspheres, wherein the erythropoietin is coated by the poly(lactic-co-glycolic acid), polylactic acid or polycaprolactone. Proven by animal experiments, the sustained release microspheres of the long-acting sustained release preparation provided by the invention have the same protective actions on the ganglionic cells of damaged retinas by single vitreous chamber injection and repeated EPO protein vitreous chamber injection, and the sustained release microspheres are capable of avoiding a series of complications caused by many times of injection and overcoming the defects of repeated intraocular injection administration and gene therapy. The long-acting sustained release preparation provided by the invention adopts intraocular local administration, can reduce the dosage and treatment cost, and can not generate adverse effects on other organs or tissues in vivo.
Owner:SHANGHAI JIAO TONG UNIV +1

Ballastless track-structured waterproof vibration-reducing flexible protecting structure and paving method thereof

ActiveCN105714621ADrain fastComprehensive three-dimensional waterproof protectionRailway tracksSurface layerBridge deck
The invention discloses a ballastless track-structured waterproof vibration-reducing flexible protecting structure and a paving method thereof. A waterproof linking layer and a buffer protecting layer are paved between the bottom of a ballastless track foundation plate and the top surface of a surface layer/bridge deck slab of a roadbed in a full-width manner. According to the ballastless track-structured waterproof vibration-reducing flexible protecting structure, by virtue of the linking layer and the buffer protecting layer which are paved on the full fracture surface, the overall stereoscopic water proofing and the integrality are realized; by regulating the dynamic modulus, the damping characteristic and the deformation adaptability of an asphalt concrete protecting layer by virtue of a special modifying enhancer, the rigidity matching and buffer vibration reducing functions are realized; and by enhancing the load diffusivity, the fatigue durability and the water damage resistance of asphalt concrete by virtue of the special modifying enhancer, the problems of premature failure, interlayer slurry extruding, disengaging, even frost heaving and the like of waterproof layers of existing ballastless track roadbeds are effectively solved, the integrality, the smoothness, the uniformity and the long-term stability of a lower base structure of a track are improved, and good and stable support is provided for a ballastless track plate, so that the fatigue life of the track plate is prolonged. The ballastless track-structured waterproof vibration-reducing flexible protecting structure is a long-lasting protection scheme.
Owner:SOUTHEAST UNIV +2

Long-acting sustained release preparation for preventing or treating retinal damage, and preparation method thereof

The invention belongs to the field of pharmaceutical preparations, and relates to a long-acting sustained release preparation for preventing or treating retinal damage, and a preparation method thereof. The long-acting sustained release preparation takes erythropoietin (EPO) as an active component, takes dextran as a protective agent for the active component, and takes poly(lactic-co-glycolic acid), polylactic acid or polycaprolactone as a coating component to prepare sustained release microspheres, wherein the erythropoietin is coated by the poly(lactic-co-glycolic acid), polylactic acid or polycaprolactone. Proven by animal experiments, the sustained release microspheres of the long-acting sustained release preparation provided by the invention have the same protective actions on the ganglionic cells of damaged retinas by single vitreous chamber injection and repeated EPO protein vitreous chamber injection, and the sustained release microspheres are capable of avoiding a series of complications caused by many times of injection and overcoming the defects of repeated intraocular injection administration and gene therapy. The long-acting sustained release preparation provided by the invention adopts intraocular local administration, can reduce the dosage and treatment cost, and can not generate adverse effects on other organs or tissues in vivo.
Owner:SHANGHAI JIAOTONG UNIV +1

Modified composite calcium sulfonate based lubricating grease composition and preparation method

InactiveCN106497641AImproved long-term mechanical stabilityReduced surface hardeningLubricant compositionCalcium hydroxideAcetic acid
The invention relates to a modified composite calcium sulfonate based lubricating grease composition and a preparation method. The composition is prepared from, by weight, 20-50% of high-alkali-value synthesized calcium sulfonate, 45-75% of basic oil, 0.1-2% of conversion agent, 0.1-3% of glacial acetic acid, 1-3% of calcium hydroxide, 0.1-5% of composite acid and 1.0-4.0% of additive, wherein the total weight is 100%. The mechanical stability of a composite calcium sulfonate base is improved and especially a thickness change value of composite calcium sulfonate based lubricating grease in the storage process is decreased by improving the varieties and contents of the conversion agent and the complex additive required in the preparation process and a preparation process of the composition, and accordingly the mechanical stability performance of the composite calcium sulfonate based lubricating grease is improved. In addition, the high-temperature anti-oxidization properties of the composite calcium sulfonate based lubricating grease is improved and can meet the requirement for long service life of the lubricating grease in the using process to the great degree. In addition, the extreme-pressure anti-abrasion and anti-rust properties of the lubricating grease can be improved.
Owner:CHINA PETROLEUM & CHEM CORP

Ecological slope protection structure and protection system as well as ecological slope construction method

The invention provides an ecological slope protection structure and protection system as well as an ecological slope construction method, and belongs to the field of slope protection. A locking anchorcable section is arranged under the potential sliding surface of a slope; the stability of a rock-soil body under the potential sliding surface is high; through the arrangement of the locking anchorcable section under the potential sliding surface, the locking anchor cable section can be protected against failure when separated from the deformed slope; one end of a free anchor cable section is connected with the locking anchor cable section; and the other end of the free anchor cable is fixed to an anchoring assembly. When the slope is deformed, the anchoring assembly and the anchor cable assembly are combined to form pull force to the slope, so that the slope can be prevented from being further deformed and destroyed; an accommodating trough used for accommodating a soil layer is encircled by the anchoring assembly and the slope, and the soil layer is capable of proving a living environment for plants; and especially for a poor geological section, root systems of the plants can go deep into gaps among rock bodies, the rock bodies can be closely connected, the integrality of the poor geological section can be improved, and then the long-term protection of a slope surface can be achieved.
Owner:HAIWEI ENG CONSTR CO LTD OF FIRSTHIGHWAY ENG CO LTD OF CCCC

Adjuvant combinations of liposomes and mycobacteriaial lipids for immunization compositions and vaccines

InactiveUS20060286128A1High protective immune responseIncreased protective immune responseAntibacterial agentsBacterial antigen ingredientsLipid formationActive agent
The present invention provides a vaccine adjuvant consisting of a combination of a surfactant i.e. dimethyldioctadecylammonium-bromide/chloride (DDA) and a lipid extract from The present invention provides a vaccine adjuvant consisting of a combination of a surfactant i.e. dimethyldeoctadecylammonium-bromide/chloride (DDA) and a lipid extract from <The present invention provides a vaccine adjuvant consisting of a combination of a surfactant i.e. dimethyldeoctadecylammonium-bromide/chloride (DDA) and a lipid extract from Mycobacterium bovis. The present invention provides a vaccine adjuvant consisting of a combination of a surfactant i.e. dimethyldeoctadecylammonium-bromide/chloride (DDA) and a lipid extract from Mycobacterium bovis<The present invention provides a vaccine adjuvant consisting of a combination of a surfactant i.e. dimethyldeoctadecylammonium-bromide/chloride (DDA) and a lipid extract from Mycobacterium bovis BCG The present invention provides a vaccine adjuvant consisting of a combination of a surfactant i.e. dimethyldeoctadecylammonium-bromide/chloride (DDA) and a lipid extract from Mycobacterium bovis BCG <The present invention provides a vaccin adjuvant consisting of a combination of a surfactant i.e. dimethyldeoctadecylammonium-bromide/chloride (DDA) and a lipid extract from Mycobacterium bovis BCG. The present invention provides a vaccine adjuvant consisting of a combination of a surfactant i.e. dimethyldeoctadecylammonium-bromide/chloride (DDA) and a lipid extract from <i>Mycobacterium bovis BCG<i>. <The present invention provides a vaccine adjuvant consisting of a combination of a surfactant i.e. dimethyldeoctadecylammonium-bromide/chloride (DDA) and a lipid extract from <i>Mycobacterium bovis BCG<i>. The total lipid extract contains both apolar lipids, polar lipids, and lipids of intermediate polarity of which the apolar lipids were found to induce the most powerful immune responses. The total lipids may be extracted with chloroform/methanol and re-dissolved in water before the addition of surfactant. This preparation may be used to induce prominent cell-mediated immune responses in a mammal in order to combat pathogens, or as a treatment for cancer.
Owner:AGGER ELSE

Bearing lubricating oil composition and preparation method thereof

The invention discloses a bearing lubricating oil composition and a preparation method thereof, and relates to the field of industrial lubricating oil. The bearing lubricating oil composition comprises the following components in parts by mass: 55-70 parts of base oil, 8-15 parts of an oiliness agent, 5-12 parts of an anti-wear reagent at extreme pressure, 5-10 parts of a friction improving agent, 3.5-6 parts of an anti-rusting agent, 3.2-5.8 parts of a viscosity index improving agent and 2.2-4.5 parts of an emulsification inhibitor. The preparation method of the bearing lubricating oil composition comprises the steps of (1) weighing; (2) implementation of a jetting mixing method; (3) ultrasonic oscillation; (4) standing. According to the bearing lubricating oil composition and the preparation method thereof which are provided by the invention, the bearing oil with high friction reduction performance at extreme pressure and lubricating performance is provided, and the corrosion resistance and rusting resistance are excellent; the bearing lubricating oil composition is excellent in low-temperature starting property and high-temperature resistance; damage, caused by friction and external erosion, to a bearing can be effectively reduced, and the service life of the bearing is prolonged.
Owner:SUZHOU CHANGSHENG ELECTROMECHANICAL
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