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Novel use of lonicera japonica

A technology of honeysuckle and honeysuckle extract, which is applied in the field of medicine and can solve problems that have not yet been reported on honeysuckle research

Inactive Publication Date: 2019-03-05
BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no research report on honeysuckle in the treatment of heart failure

Method used

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  • Novel use of lonicera japonica
  • Novel use of lonicera japonica
  • Novel use of lonicera japonica

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] The preparation of embodiment 1 honeysuckle extract

[0041] Take the honeysuckle medicinal material, extract twice with 10 times the amount of water, 2.0 hours each time, filter the extract, combine the filtrate, concentrate under reduced pressure to a thick paste with a relative density of 1.24g / mL, and set aside.

Embodiment 2

[0042] The preparation of embodiment 2 honeysuckle extract

[0043] Take honeysuckle medicinal material, ultrasonically extract 2 times with 70% ethanol, each time for 40 minutes, filter the extract, combine the filtrates, recover ethanol, dry under reduced pressure, and set aside.

Embodiment 3

[0044] The preparation of embodiment 3 honeysuckle extract

[0045] Take honeysuckle medicinal material, ultrasonically extract 2 times with 70% ethanol, 40 min each time, filter the extract, concentrate under reduced pressure until it has no alcohol smell, then extract with petroleum ether, chloroform, ethyl acetate, and n-butanol in sequence to obtain Petroleum ether extract, chloroform extract, ethyl acetate extract, n-butanol extract.

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Abstract

The invention aims at providing lonicera japonica, lonicera japonica extract and a novel use of a traditional Chinese medicine composition comprising the lonicera japonica. The research proves that the lonicera japonica has the effect for inhibiting the excessive thickness of a wall, delaying the cardiac remodeling, improving the heart function and improving the myocardial fibrosis.

Description

technical field [0001] The invention relates to a new application of honeysuckle, in particular to a new application of honeysuckle in treating heart failure, and belongs to the field of medicine. Background technique [0002] Honeysuckle, also known as double flower, honeysuckle flower, etc., is the dry flower bud or the first flower of Lonicera japonica Thunb. Harvest and dry before the flowers open in early summer. Sweet and cold in nature, it returns to the lung, heart and stomach meridian, has the effect of clearing away heat and detoxification, and dispelling wind-heat. It has a long history of use and is known as "antibiotics in traditional Chinese medicine". Honeysuckle is widely distributed in our country, with complex chemical components and various functions. In addition to medicinal purposes, it is also widely used in food, cosmetics and health care products and other industries. [0003] Since the 1960s, researchers at home and abroad have done a lot of resea...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/355A61K36/481A61K36/537A61P9/00A61P9/04A23L2/38A23L33/105
CPCA23L2/38A23L33/105A61K36/232A61K36/355A61K36/481A61K36/484A61K36/537A23V2002/00A61K2300/00A23V2200/326A23V2250/21A23V2300/14A23V2250/642A23V2250/6422
Inventor 王伟刘斌郭淑贞柴欣楼任莹璐张惠敏
Owner BEIJING UNIV OF CHINESE MEDICINE
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