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Method for establishing model for obtaining glomerular filtration rate and application

A technology of glomerular filtration rate and establishment method, which can be applied in medical simulation, health index calculation, medical informatics and other directions, and can solve the problem of inaccurate estimation of glomerular filtration rate.

Active Publication Date: 2019-03-29
THE THIRD XIANGYA HOSPITAL OF CENT SOUTH UNIV
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Problems solved by technology

[0003] The technical problem to be solved by the present invention is: inaccurate estimation of glomerular filtration rate for the Chinese population

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  • Method for establishing model for obtaining glomerular filtration rate and application
  • Method for establishing model for obtaining glomerular filtration rate and application
  • Method for establishing model for obtaining glomerular filtration rate and application

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Embodiment Construction

[0027] In order to make the above objects, features and advantages of the present invention more comprehensible, specific implementations of the present invention will be described in detail below in conjunction with the accompanying drawings. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. However, the present invention can be implemented in many other ways different from those described here, and those skilled in the art can make similar improvements without departing from the connotation of the present invention, so the present invention is not limited by the specific implementations disclosed below.

[0028] The patient data collected in this specific embodiment comes from the Third Xiangya Hospital (TXH) and the Second Xiangya Hospital (SXH) of Central South University (Changsha, Hunan Province) in central China (Changsha City, Hunan Province), and the First Affiliated Hospital (FX...

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Abstract

The invention relates to a method for establishing a model for obtaining the glomerular filtration rate of Chinese population and the application thereof. The establishing method comprises the following steps: S1, carrying out single factor analysis on a plurality of candidate independent variables corresponding to the glomerular filtration rate known by a patient by using least square method linear regression, and screening out a plurality of first independent variables; S2, carrying out multielement analysis on the first independent variables by using multiple linear regression modeling, andsimplifying the quantity of the first independent variables to establish a first model, wherein the function expression of the first model is GFR=94047.95*0.8892828*N<-0.22630>*C<-0.52474>*L<-0.92495>*H<0.28309>, GFR indicates the glomerular filtration rate, a is a coefficient related to sex, L indicates the concentration of creatinine, L indicates the concentration of chlorine ions, and H indicates the concentration of red cells. The model can accurately obtain the glomerular filtration rate of patients in Chinese population. The invention discloses the application of the model for obtaining the glomerular filtration rate of Chinese population in obtaining the glomerular filtration rate of Chinese population.

Description

technical field [0001] The invention relates to the field of medical and health technologies, in particular to a method for establishing a model for obtaining glomerular filtration rate and its application. Background technique [0002] Kidney disease is a worldwide public health disease with a high incidence and heavy burden. In 2012, there were 120 million chronic kidney disease patients in my country, with an incidence rate of 10.8%. Among hospitalized patients in China, acute kidney injury (AKI) accounted for 2.4%–8.1% of complications, and the mortality rate of patients with acute kidney injury was as high as 18.6%. –28.5%. In China, the average annual treatment cost per dialysis patient is US$14,000. Therefore, rapid and accurate assessment of renal function and changes in renal function is essential for the prevention, diagnosis and treatment of renal diseases. The glomerular filtration rate (Glomerular Filtration Rate, GFR) is the most accurate indicator for evalua...

Claims

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Application Information

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IPC IPC(8): G16H50/30G16H50/50
CPCG16H50/30G16H50/50
Inventor 左笑丛易翼虎尹文俊李岱阳张毕奎赵军朱超男
Owner THE THIRD XIANGYA HOSPITAL OF CENT SOUTH UNIV
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