Composition with repairing and anti-aging effects, and preparation method and application thereof

A composition and anti-aging technology, which is applied in skin care preparations, pharmaceutical formulas, cosmetic preparations, etc., can solve the problems of limited skin absorption effect and unsatisfactory anti-aging effect, and achieve a reasonable and easy-to-absorb formula Effect

Inactive Publication Date: 2019-04-12
广州那比昂生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the absorption effect of the skin is

Method used

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  • Composition with repairing and anti-aging effects, and preparation method and application thereof
  • Composition with repairing and anti-aging effects, and preparation method and application thereof
  • Composition with repairing and anti-aging effects, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] This embodiment provides a composition (I) with repairing and anti-aging effects, which includes the following components by weight percentage:

[0060]

[0061]

[0062] Its preparation method comprises the following steps:

[0063] (1) Ultrasonic mixing of soybean lecithin, cholesterol and ethanol to obtain ethanol solution A; after ultrasonic mixing of squalane, ubiquinone, ceramide 3, ceramide 6II, cypress essential oil and ethanol, use 0.22 μm organic Filter through a microporous membrane to obtain ethanol solution B;

[0064] (2) Mix ethanol solution A and ethanol solution B into a syringe, drop them into a phosphate buffer with a pH value of 7.4 at a constant speed of 0.25mL / s at 50°C, and give magnetic stirring at the same time. 200r / min;

[0065] (3) Ethanol was evaporated under reduced pressure at 35°C; the product was incubated at 50°C for 2h, then ultrasonically pulverized in an ice bath for 10min, passed through a 0.45μm microporous filter membrane,...

Embodiment 2

[0068] This embodiment provides a composition (II) with repairing and anti-aging effects, which includes the following components by weight percentage:

[0069] components

weight percentage

Deionized water

margin

1,2-pentanediol

5.0

1,3-Propanediol

15.0

1,2-Hexanediol

2.0

Polyacrylate Crosspolymer-6

0.5

Squalane

8.0

ubiquinone

2.00

Soy lecithin

10.0

cholesterol

3.0

Ceramide 3

1.0

Cypress essential oil

0.25

Carnosine

1.0

Sodium hyaluronate (large: medium: small = 1:2:15)

0.25

[0070] Its preparation method comprises the following steps:

[0071] (1) Ultrasonic mixing of soybean lecithin, cholesterol, and ethanol to obtain ethanol solution A; after ultrasonic mixing of squalane, ubiquinone, ceramide 3, cypress essential oil, and ethanol, use a 0.22 μm organic microporous filter membrane Filter to obtain ethanol solution B;

[0072...

Embodiment 3

[0076] This embodiment provides a composition (III) with repairing and anti-aging effects, which includes the following components by weight percentage:

[0077]

[0078]

[0079] Its preparation method comprises the following steps:

[0080] (1) Ethanol phospholipids, cholesterol and ethanol were mixed ultrasonically to obtain ethanol solution A; squalane, ubiquinone, ceramide 1A, ceramide 2, ceramide 3, ceramide 4, cypress essential oil and ethanol were ultrasonically After mixing, filter with a 0.22 μm organic microporous membrane to obtain ethanol solution B;

[0081] (2) Mix ethanol solution A and ethanol solution B into a syringe, drop them into a phosphate buffer with a pH value of 7.4 at a constant speed of 0.24mL / s at 50°C, and give magnetic stirring at the same time. 200r / min;

[0082](3) Ethanol was evaporated under reduced pressure at 35°C; the product was incubated at 40°C for 1.5h, then ultrasonically pulverized in an ice bath for 10min, passed through a ...

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Abstract

The present invention relates to a composition with repair and anti-aging effects, and a preparation method and application thereof. The composition comprises the following components in percentage byweight: humectant 10-50%, thickener 0.1-1%, squalane 0.1-10%, ubiquinone 0.01-3%, lecithin 1-20%, cholesterol 1-15%, ceramide 0.1-5%, cypress essential oil 0.01-0.3%, carnosine 0.1-3%, sodium hyaluronate 0.01-0.5%, and deionized water as the balance. The preparation method comprises the steps of: dissolving fat-soluble components of the composition in ethanol, preparing a liposome by using an ethanol injection method, and mixing water-soluble components of the composition with the liposome to obtain the composition with repairing and anti-aging effects. The composition is easily absorbed by skin and has significant repairing and anti-aging benefits.

Description

technical field [0001] The field of cosmetics of the present invention relates to a composition and its preparation method and application, in particular to a composition with repairing and anti-aging effects and its preparation method and application. Background technique [0002] Aging, also known as aging, is an inevitable stage in the process of life activities, and skin aging is the most obvious in the aging process of the body. Skin aging not only causes wrinkles, sagging and pigmentation, but also reduces epidermal metabolism, impaired epidermal repair ability and weakened barrier protection ability. Therefore, anti-aging cosmetics have become one of the categories that consumers urgently need. [0003] CN102085168A discloses an anti-aging cosmetic and a preparation method thereof. The cosmetic contains 1-5% of solid oil, 9.5-20% of liquid oil, 1-5% of emulsifier, 10-22% of moisturizing agent, Luremin TM 0.5-4.5%, BIOTIGHTENER 0.5-4.5%, the balance is water. The an...

Claims

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Application Information

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IPC IPC(8): A61K8/92A61K8/73A61K8/68A61K8/64A61K8/63A61K8/55A61K8/35A61K8/31A61K8/34A61Q19/00A61Q19/08
CPCA61K8/31A61K8/345A61K8/355A61K8/553A61K8/63A61K8/64A61K8/68A61K8/735A61K8/922A61Q19/00A61Q19/08
Inventor 胡兴国孔秋婵陈庆生吴知情胡根华
Owner 广州那比昂生物科技有限公司
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