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31results about How to "Significant anti-aging effect" patented technology

Preparation method and application of mussel oligopeptide

The present invention discloses a preparation method and an application of a mussel oligopeptide, and belongs to the field of marine biotechnology application. The preparation method comprises: adopting mytilus edulis as a raw material, and adopting an alkaline cold extraction method to obtain mussel protein from mussel freeze-drying powder; and carrying out composite enzymolysis of protein to obtain mixed polypeptides, carrying out ultra-filtration to obtain the oligopeptide, adopting aging mouse models to carry out a series of anti-aging animal experiments and behavioral experiments, and carrying out a drosophila survive experiment to prove aging delay activity of the mussel oligopeptide so as to create a new approach for achievement of scientific and high-value mussel utilization. Compared with the method in the prior art, the method of the present invention has the following advantages that: the mussel protein is extracted and prepared, the optimal protease and the preferred process are adopted to carry out enzymolysis purification on the mussel protein, decomposition on the mussel protein molecule structure due to the high temperature is avoided, the grading of the mussel polypeptide at the molecular weight level is achieved, and the obtained mussel oligopeptide has the pure and good aging delay effect.
Owner:JIANGSU UNIV

Antioxidation SOD oral spray and preparing method thereof

The invention relates to an antioxidation SOD oral spray. The oral spray is prepared, by weight, 0.1-2.0% of superoxide dismutase (SOD), 1.0-5.0% of vitamin C, 1.0-3.5% of trehalose, 0.2-1.0% green tea extract and others is distilled water. The preparing method comprises the steps of 1, weighing each raw material of the formula ratio respectively; 2, dissolving the vitamin C, the green tea extract EGCG and the trehalose into the distilled water and filtering, adopting conventional high temperature sterilization method and cooling to below 25 DEG C to get mixed liquor; 3, adopting conventional radiation sterilization method for SOD and placing the sterilized SOD into the mixed liquor made in step of 2 under the sterile working environment, mixing and dissolving to get mixed enzyme solution; 4, canning the mixed enzyme solution into a spraying bottle with quantitative valves to get the antioxidation SOD oral spray and store the antioxidation SOD oral spray below 25 DEG C. The antioxidation SOD oral spray and preparing method thereof make use of mutual protection and interaction between the SOD and the vitamin C and between the green tea extract EGCG and the trehalose to make the oral spray with good stability, antioxidant and anti-aging functions. The oral spray is absorbed directly by the sublingual mucosa, conveniently to take, improving bioavailability and efficacy of SOD significantly with wide and broad market in future.
Owner:陈石良

Vibration massage eye cream containing ganoderma lucidum fermentation filtrate and preparation method of vibration massage eye cream

The invention discloses vibration massage eye cream containing a ganoderma lucidum fermentation filtrate. The vibration massage eye cream is prepared from the components in parts by weight: a component A: deionized water, a thickener, a humectant, a preservative and sodium hyaluronate, a component B: an emollient, jojoba seed oil, wheat germ oil, an emulsifier, tocopherol acetate, ascorbyl tetraisopalmitate and tocopherol, a component C: a alpine vegetation extract, a centella asiatica extract, the ganoderma lucidum fermentation filtrate, ubiquinone, a pHconditioning agent and the deionized water, and a component D: pullulan, a wild soy protein, essential oil and acetyl tetrapeptide-5. According to the vibration massage eye cream, traditional Chinese medicine herbs and high-end scientificand technological ingredients are combined, the vibration massage eye cream is rich in Chinese ganoderma lucidum fermentation filtrate and other plant active substances and other functional ingredients, dark circles under eyes are reduced, skin elasticity is improved, synthesis of collagen is promoted, vitality of eye cells is improved, and thus skin around the eyes looks more elastic and youthful.
Owner:DOCTOR PLANT GUANGDONG BIOTECHNOLOGY CO LTD

Preparation and application of PCL-PLA (polycaprolactone-polylactic acid) tissue engineering composite scaffold with liver cell anti-aging function

The invention discloses a PCL-PLA (polycaprolactone-polylactic acid) tissue engineering composite scaffold with a liver cell anti-aging function. The PCL-PLA tissue engineering composite scaffold is made of scaffold materials on the basis of PCL-PLA, and polyacrylamide, IGF (insulin-like growth factors), TNF-alpha (tumor necrosis factors-alpha) are subjected to photo-grafting to carry out synergetic joint modification to form the PCL-PLA tissue engineering composite scaffold. The PCL-PLA tissue engineering composite scaffold has the advantages that materials with positive charge and dual growth factors are jointly modified on the basis of the three-dimensional scaffold materials, accordingly, obvious cell anti-aging effects can be realized by the prepared PCL-PLA tissue engineering composite scaffold [PCL-PLA-PAAm (polyacrylamide)-IGF / TNF-alpha], cells can be attached to the scaffold to grow advantageously, and tissues and even organs can be possibly formed by the cells; the cells are cultivated on the three-dimensional scaffold, the PCL-PLA tissue engineering composite scaffold effectively conforms to internal human cell life environments, growth states of the cells can be obviously improved, the PCL-PLA tissue engineering composite scaffold has a practical significance on clinical application, positive promotion effects can be realized for liver tissue engineering research, and directions can be provided for cell anti-aging research in tissue engineering.
Owner:SOUTH CHINA NORMAL UNIVERSITY

Preparation method of lycopene composition with anti-aging effect

PendingCN112569249AImprove lifespan and climbing abilityRaise the level of MDAHydrocarbon active ingredientsAntinoxious agentsBlood serumMolecular biology
The invention discloses a preparation method of a lycopene-containing composition with an anti-aging effect, which comprises the following steps: mixing lycopene oleoresin with a small amount of absolute ethyl alcohol to obtain lycopene oleoresin alcoholate, putting the nicotinamide mononucleotide into a fluidized bed granulator, atomizing the lycopene oleoresin alcoholate by a nozzle through compressed air, spraying the lycopene oleoresin alcoholate onto nicotinamide mononucleotide powder in a fluidized state on the fluidized bed layer, wetting and fully mixing the lycopene oleoresin alcoholate and the nicotinamide mononucleotide powder, and performing flow granulation, wherein the conditions for spray granulation are as follows: the atomizing speed of a nozzle is 40-100mL/min, and the atomizing particle size is 10-12 [mu]m. The anti-aging composition prepared by the method disclosed by the invention can effectively prolong the service life of the drosophila melanogaster, improve theclimbing capacity of the drosophila melanogaster, effectively improve the MDA level of rat serum and the SOD activity of the rat serum, and has a remarkable anti-aging effect. Moreover, the granular product is high in content of effective components and good in stability.
Owner:NANJING ZHONGKE GRP CORP LTD +1

Sheep placenta extracting solution with anti-aging function as well as preparation method and application thereof

The invention discloses a sheep placenta extracting solution with an anti-aging function as well as a preparation method and application thereof. The preparation method comprises the following steps of S1, taking sheep placenta in an embryo period, separating cotyledons, discarding fetal membranes, cleaning the cotyledons with normal saline, and dicing the cotyledons; S2, soaking the cotyledon blocks in a peroxyacetic acid solution, and then cleaning the cotyledon blocks with purified water; S3, adding a taurine solution into the cotyledon blocks, and carrying out crushing and homogenizing toobtain slurry; S4, oscillating and centrifuging the slurry, and separately collecting supernatant and precipitate; S5, adding taurine into the precipitate, carrying out negative pressure cavitation extraction, performing centrifuging, and collecting the supernatant; S6, mixing the supernatant, adjusting the pH value, oscillating, centrifuging, and collecting the supernatant; S7, adjusting the pH value of the supernatant, carrying out complementing and inactivating, then adjusting the pH value, performing centrifuging, and collecting supernatant; and S8, carrying out ultrafiltration concentration on the supernatant, and performing filtering and degerming to obtain the product. The extract disclosed by the invention has the effects of moisturizing, resisting wrinkles, delaying senescence andenhancing the skin immune function when being applied to cosmetics, and has a wide market prospect.
Owner:CHENGDU QINGKE BIOTECH

Extraction technology of moringa flavonoid glycosides compound and application thereof in neck mask

The invention relates to an extraction technology of a moringa flavonoid glycosides compound and an application thereof in a neck mask, and belongs to the technical field of the plant chemistry and cosmetics. The extraction technology comprises the following steps: extracting a water-soluble extract from a moringa ethanol extract, separating and purifying by using a medium-pressure reverse phase silicagel column chromatography, a SephadexLH-20 gel column chromatography, and a semi-preparation high performance liquid chromatography successively. The moringa flavonoid glycosides compound as shown in a formula (I) is obtained. The compound has good anti-aging, anti-oxidant and anti-inflammation functions. The compound is used in the neck mask, and compounded with substances of moringa seed oil, sodium hyaluronate and the like, has the remarkable moisture-preserving, repairing, anti-inflammatory and anti-aging effects to neck skin, is capable of apparently improving a neck skin type, wherein the skin is fine, delicate and glossy, and apparently reducing wrinkles, and has the good treatment effect to neck acne and the like, wherein while a small wound is caused by acne extrusion, neck mask liquid of the invention can also be used, so the compound is wider in application range.
Owner:YUNNAN AGRICULTURAL UNIVERSITY +1
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