31results about How to "Significant anti-aging effect" patented technology

The invention discloses a hyaluronic acid anti-aging composition and a preparation method and application thereof. The composition comprises a hydrolyzed hyaluronic acid and salts thereof and two hyaluronic acids with weight-average molecular weight and salts thereof. According to multiple tests of skin moisture content, skin elasticity, depth of wrinkles and the like, an optimum ratio with an obvious anti-aging effect is finally determined. The weight ratio of the hydrolyzed hyaluronic acid and salts thereof in the composition is 60-62%; the weight ratio of hyaluronic acid with low molecular weight and salts thereof in the composition is 18-20%; and the weight ratio of hyaluronic acid with high molecular weight and salts thereof in the composition is 18-20%. The composition has the anti-aging effects of three-dimensional moisturizing, scavenging free radicals, repairing cells, restoring skin elasticity and the like, and can be used in cosmetics and cleaning products of all the forms.

The present invention discloses a preparation method and an application of a mussel oligopeptide, and belongs to the field of marine biotechnology application. The preparation method comprises: adopting mytilus edulis as a raw material, and adopting an alkaline cold extraction method to obtain mussel protein from mussel freeze-drying powder; and carrying out composite enzymolysis of protein to obtain mixed polypeptides, carrying out ultra-filtration to obtain the oligopeptide, adopting aging mouse models to carry out a series of anti-aging animal experiments and behavioral experiments, and carrying out a drosophila survive experiment to prove aging delay activity of the mussel oligopeptide so as to create a new approach for achievement of scientific and high-value mussel utilization. Compared with the method in the prior art, the method of the present invention has the following advantages that: the mussel protein is extracted and prepared, the optimal protease and the preferred process are adopted to carry out enzymolysis purification on the mussel protein, decomposition on the mussel protein molecule structure due to the high temperature is avoided, the grading of the mussel polypeptide at the molecular weight level is achieved, and the obtained mussel oligopeptide has the pure and good aging delay effect.

The invention provides a fat extract without additive components as well as a preparation method and application of the fat extract. Specifically, the invention provides application of the fat extractwithout additive components in preparation of a composition or product having the following one or more applications: (a) promoting proliferation of fibroblasts; (b) promoting the aging resistance ofthe fibroblasts; and (c) promoting the production of type I collagen in the fibroblasts. The invention also provides a preparation method of the fat extract without the additive components, a medicine or cosmetic composition containing the fat extract without the additive components, and a method for culturing fibroblasts in vitro. The fat extract without additive components can efficiently and synergistically inhibit skin aging, prevent fibroblast apoptosis, promote fibroblast proliferation and collagen synthesis, and promote skin rejuvenation.

The invention relates to an antioxidation SOD oral spray. The oral spray is prepared, by weight, 0.1-2.0% of superoxide dismutase (SOD), 1.0-5.0% of vitamin C, 1.0-3.5% of trehalose, 0.2-1.0% green tea extract and others is distilled water. The preparing method comprises the steps of 1, weighing each raw material of the formula ratio respectively; 2, dissolving the vitamin C, the green tea extract EGCG and the trehalose into the distilled water and filtering, adopting conventional high temperature sterilization method and cooling to below 25 DEG C to get mixed liquor; 3, adopting conventional radiation sterilization method for SOD and placing the sterilized SOD into the mixed liquor made in step of 2 under the sterile working environment, mixing and dissolving to get mixed enzyme solution; 4, canning the mixed enzyme solution into a spraying bottle with quantitative valves to get the antioxidation SOD oral spray and store the antioxidation SOD oral spray below 25 DEG C. The antioxidation SOD oral spray and preparing method thereof make use of mutual protection and interaction between the SOD and the vitamin C and between the green tea extract EGCG and the trehalose to make the oral spray with good stability, antioxidant and anti-aging functions. The oral spray is absorbed directly by the sublingual mucosa, conveniently to take, improving bioavailability and efficacy of SOD significantly with wide and broad market in future.

The invention discloses vibration massage eye cream containing a ganoderma lucidum fermentation filtrate. The vibration massage eye cream is prepared from the components in parts by weight: a component A: deionized water, a thickener, a humectant, a preservative and sodium hyaluronate, a component B: an emollient, jojoba seed oil, wheat germ oil, an emulsifier, tocopherol acetate, ascorbyl tetraisopalmitate and tocopherol, a component C: a alpine vegetation extract, a centella asiatica extract, the ganoderma lucidum fermentation filtrate, ubiquinone, a pHconditioning agent and the deionized water, and a component D: pullulan, a wild soy protein, essential oil and acetyl tetrapeptide-5. According to the vibration massage eye cream, traditional Chinese medicine herbs and high-end scientificand technological ingredients are combined, the vibration massage eye cream is rich in Chinese ganoderma lucidum fermentation filtrate and other plant active substances and other functional ingredients, dark circles under eyes are reduced, skin elasticity is improved, synthesis of collagen is promoted, vitality of eye cells is improved, and thus skin around the eyes looks more elastic and youthful.

The invention discloses essence with effects of whitening, defying age and activating skin and a preparation method of the essence. The essence comprises the following components: a wetting agent, acrylic (acrylate) / C10-30 alkyl acrylate crosslinked polymers, 2-oleamido-1,3-octodecanediol, mulberry bark extract, irkutsk anemone rhizome extract, persimmon leaf extract, growth-factor-containing lipidosome, capryloyl salicylic acid, cholesterol polyether-24, a thickening agent, a preservative and the balance of deionized water. The essence with effects of whitening, defying age and activating skin disclosed by the invention is scientific in ratio of various components, the various components achieve obvious synergistic effects, and the essence can achieve the effects of efficiently moisturizing, supplying nutrition to skin, promoting skin metabolism, reducing stains, effectively removing lines and wrinkles, retarding skin aging, improving skin sagging, brightening and tightening skin, moisturizing for a long time, enabling the skin to be moisturized, smooth and enriched in elasticity and improving the skin youth.

The invention discloses a PCL-PLA (polycaprolactone-polylactic acid) tissue engineering composite scaffold with a liver cell anti-aging function. The PCL-PLA tissue engineering composite scaffold is made of scaffold materials on the basis of PCL-PLA, and polyacrylamide, IGF (insulin-like growth factors), TNF-alpha (tumor necrosis factors-alpha) are subjected to photo-grafting to carry out synergetic joint modification to form the PCL-PLA tissue engineering composite scaffold. The PCL-PLA tissue engineering composite scaffold has the advantages that materials with positive charge and dual growth factors are jointly modified on the basis of the three-dimensional scaffold materials, accordingly, obvious cell anti-aging effects can be realized by the prepared PCL-PLA tissue engineering composite scaffold [PCL-PLA-PAAm (polyacrylamide)-IGF / TNF-alpha], cells can be attached to the scaffold to grow advantageously, and tissues and even organs can be possibly formed by the cells; the cells are cultivated on the three-dimensional scaffold, the PCL-PLA tissue engineering composite scaffold effectively conforms to internal human cell life environments, growth states of the cells can be obviously improved, the PCL-PLA tissue engineering composite scaffold has a practical significance on clinical application, positive promotion effects can be realized for liver tissue engineering research, and directions can be provided for cell anti-aging research in tissue engineering.

The invention relates to non-clarified type NFC aronia melanocarpa compound juice. The compound juice comprises components in parts by weight as follows: 50-80 parts of aronia melanocarpa juice and 20-50 parts of other NFC juices. Aronia melanocarpa is taken as a main characteristic component of the juice and compounded with the other NFC juices, the other juices specifically comprise one or moreof mulberry juice, grape juice, lycium ruthenicum juice, jujube juice and apple juice, no pigment or essence is added, and the unique flavor of the aronia melanocarpa is reserved greatly; meanwhile, anthocyanin and flavonoids contained in the aronia melanocarpa have very high anti-oxidation and anti-inflammatory functions, so that the product not only reserves natural active components, but also has good taste and can meet multiple demands of consumers; and the finished NFC compound juice has rich nutrients, moderate sourness and sweetness and significant anti-oxidation, anti-inflammatory andanti-aging functions.

The invention belongs to the field of preparation of a lipstick, and in particular relates to a jasmine tea lipstick. The jasmine tea lipstick consists of the following raw materials in parts by weight: 8-10 parts of a jasmine tea extract, 12-15 parts of peppermint, 15-20 parts of Chinese toon sprouts, 12-13 parts of honey, 19-22 parts of beeswax and 6-8 parts of apricot kernel oil. The jasmine tea lipstick is quite significant in effects on resisting bacteria and diminishing inflammation, moistening lips, resisting radiation and aging, and the jasmine tea lipstick is easy to absorb, mild in property and non-irritant.

The invention relates to an anti-aging lipid nanoparticle emulsion for skin and a preparation method of the anti-aging lipid nanoparticle emulsion. The emulsion comprises the following components by mass percentage: 0.5-15.0% of anti-aging mixture for skin, 6.5-26.6% of lipid material, 6.0-13.2% of emulsifying agent, 5.0-25.0% of ethanol and the balance of water, wherein the anti-aging mixture for skin is made up of resveratrol, dimethoxytolyl propylresorcinol and salicyloyl phytosphingosine. The method mainly comprises the steps of preparing a liquid state oil phase and an aqueous phase, and carrying out high pressure homogenization on the liquid state oil phase and the aqueous phase with temperature of 75-85 DEG.C, pressure of 80-150 MPa and stirring speed of 600rpm. The invention has the following advantages: the contents of the loaded resveratrol, dimethoxytolyl propylresorcinol and salicyloyl phytosphingosine are high, the stability of the emulsion is good, the anti-aging effect for skin is remarkable, the transdermal absorption rate of the effective components is high, and the emulsion is conveniently added into a formula of the cosmetics via a cooling distribution.

The invention relates to an extraction process of a moringa fat-soluble polyphenol compound and application of the compound, and belongs to the fields of phytochemical techniques and cosmetics. According to the extraction process, a fat-soluble polyphenol extract is extracted from an alcohol extract of moringa; then, separation and purification are performed by sequentially adopting medium-pressure reversed-phase silica gel column chromatography, Sephadex LH-20 gel column chromatography, and semi-preparative high performance liquid chromatography to obtain the moringa fat-soluble polyphenol compound as shown in a formula (I). The compound has good anti-aging, antioxidant and anti-inflammatory effects. When the compound is applied to neck cream, and is compounded with substances such as moringa seed oil, moringa oil and chondroitin sulfate, remarkable moisturizing, repairing, anti-inflammatory and anti-aging efficacy on neck skin can be achieved; the neck skin is obviously improved; meanwhile, a very good curative effect on neck wrinkles, acne and the like is achieved; the application range is relatively wide.

The invention belongs to the field of cosmetics and particularly relates to an anti-aging composition and preparation and application thereof. The anti-aging composition is prepared from the following ingredients in parts by weight: 1 to 3 parts of hydrolyzed pearl powder, 1 to 3 parts of dioscorea villosa root extract, 0.5 to 2 parts of acetyl hexapeptide-8, 0.5 to 2 parts of acetyl octapeptide-3 and 0.5 to 2 parts of nonapeptide-1. Experiments prove that the anti-aging composition disclosed by the invention has an extremely obvious removing effect on quiescent wrinkles, dynamic wrinkles and posture extrusion wrinkles, meanwhile can obviously promote multiplication of human skin fibroblast, extremely obviously promotes synthesis of I and III type collagen and extremely obviously inhibits expression of MMP1 and MMP3.

The invention discloses a preparation method of a lycopene-containing composition with an anti-aging effect, which comprises the following steps: mixing lycopene oleoresin with a small amount of absolute ethyl alcohol to obtain lycopene oleoresin alcoholate, putting the nicotinamide mononucleotide into a fluidized bed granulator, atomizing the lycopene oleoresin alcoholate by a nozzle through compressed air, spraying the lycopene oleoresin alcoholate onto nicotinamide mononucleotide powder in a fluidized state on the fluidized bed layer, wetting and fully mixing the lycopene oleoresin alcoholate and the nicotinamide mononucleotide powder, and performing flow granulation, wherein the conditions for spray granulation are as follows: the atomizing speed of a nozzle is 40-100mL / min, and the atomizing particle size is 10-12 [mu]m. The anti-aging composition prepared by the method disclosed by the invention can effectively prolong the service life of the drosophila melanogaster, improve theclimbing capacity of the drosophila melanogaster, effectively improve the MDA level of rat serum and the SOD activity of the rat serum, and has a remarkable anti-aging effect. Moreover, the granular product is high in content of effective components and good in stability.

The invention relates to application of a trichosanthes kirilowii Maxim and semen armeniacae amarae compound extract or a trichosanthes kirilowii Maxim and semen armeniacae amarae compound refined product in preparation of cosmetics and medicines for improving inflammatory aging. The trichosanthes kirilowii Maxim and semen armeniacae amarae compound extract and the compound refined product have weak cytotoxic effect on macrophages and are high in safety. The obvious anti-inflammatory and anti-aging effects are shown on an LPS (Lipopolysaccharide) and H2O2 induced macrophage inflammation and aging model.

The invention provides rosa plant fermentation liquor as well as a preparation method, a composition and application thereof, and relates to the technical field of skin care product production. The invention relates to a preparation method of rosa plant fermentation liquor, which comprises the following steps: crushing rosa plant flowers, soaking in warm water, inoculating mixed koji enzyme bacterial koji for pre-fermentation, and then inoculating saccharomycopsis fibuligera, aroma-producing yeast and saccharomyces cerevisiae for fermentation to obtain the rosa plant fermentation liquor. The invention also provides a rosa plant fermentation broth, a composition and an application of the rosa plant fermentation broth and the composition. Additional enzymolysis is not needed before fermentation, production steps and cost are reduced, and the prepared rosa plant fermentation liquor is low in alcoholic strength, suitable for being applied to skin care products and remarkable in whitening, moisturizing, anti-oxidation and anti-aging effects.

The invention discloses an anti-aging food health tea electuary belonging to the field of nutritional foods and aims at achieving the purposes of being good in effect and quick in taking effect. The anti-aging food health tea electuary is prepared from longan aril, Chinese caterpillar fungus, tomatoes, epimedium, black tea and other raw materials; and the anti-aging food health tea electuary has the effects of supporting body resistance, reinforcing qi and nourishing blood and anti-aging, and has the advantages of being good in effect and quick in taking effect.

The invention discloses an external composition for resisting skin aging and application thereof, and belongs to the technical field of daily cosmetics. The external composition is formed by compounding a bletilla striata polysaccharide extract, an atractylodes macrocephala polysaccharide extract, an ampelopsis japonica polyphenol extract and a lotus flavone extract according to the mass ratio of (1-4): (1-6): (1-3): (1-3), the composition is prepared into emulsion to be used for human skin, a stronger skin aging resisting effect is shown, the four extracts have a synergistic interaction effect, and the anti-skin aging effect of the composition is obviously improved.

The invention discloses a rice anti-aging lodging-resistant agent and an application method thereof. The rice anti-aging lodging-resistant agent is prepared from 5.0 to 20.0 percent of soluble organicchelated potassium silicate, 1.0 to 5.0 percent of prohexadione calcium, 3.0 to 6.0 percent of glycol, 1.0 to 3.0 percent of anionic surfactants, 1.0 to 2.0 percent of stabilizing agents, 0.1 percentof antifoaming agents and the balance of water. The rice anti-aging lodging-resistant agent is diluted by water for 300 to 400 times by water; organic silicon surfactants diluted for 3000 to 6000 times are added; after the sufficient and uniform stirring, the fertilizer is sprayed onto leaf sheaths; during the spray application, the speed is properly accelerated; the leaves are wetted without drip injectionping; during the application after rice full heading, the application time interval every time is more than 7 days or above. The lodging-resistant capability is enhanced through prolongingthe leaf sheath vaginant lamina effects; the defects of plant dwarf and high biomass realization difficulty due to dwarfing agents can be avoided.

The invention discloses three-color Furong honey powder. The honey powder is prepared from the following components in percentage of 50-60% of silica, 20-25% of synthetic fluorophlogopite, 8-12% of aluminum starch octenylsuccinate, 4-6% of polydimethylsiloxane, 3-5% of polymethyl methacrylate, 0.9-1% of triethoxyoctylsilane, 0.1-0.3% of tocopheryl acetate, 0.01% of sodium hyaluronate, 0.01% of nicotinamide, 0.01% of jellyfish extract, 0.01% of a combination of water, glycerin and tripeptide-1 copper, 0.7% of phenoxyethanol, 0.1% of ethylhexylglycerin and 0.4-1% of a coloring agent, wherein the silica is spherical porous silicon dioxide, and the average particle size of the spherical porous silicon dioxide is 5-10 microns; and the refractive index of the spherical porous silicon dioxide is 1.544. The Furong honey powder has the technical effects of improving the skin fine line fading effect and the oil absorption and anti-oxidation effects.

The invention discloses a sheep placenta extracting solution with an anti-aging function as well as a preparation method and application thereof. The preparation method comprises the following steps of S1, taking sheep placenta in an embryo period, separating cotyledons, discarding fetal membranes, cleaning the cotyledons with normal saline, and dicing the cotyledons; S2, soaking the cotyledon blocks in a peroxyacetic acid solution, and then cleaning the cotyledon blocks with purified water; S3, adding a taurine solution into the cotyledon blocks, and carrying out crushing and homogenizing toobtain slurry; S4, oscillating and centrifuging the slurry, and separately collecting supernatant and precipitate; S5, adding taurine into the precipitate, carrying out negative pressure cavitation extraction, performing centrifuging, and collecting the supernatant; S6, mixing the supernatant, adjusting the pH value, oscillating, centrifuging, and collecting the supernatant; S7, adjusting the pH value of the supernatant, carrying out complementing and inactivating, then adjusting the pH value, performing centrifuging, and collecting supernatant; and S8, carrying out ultrafiltration concentration on the supernatant, and performing filtering and degerming to obtain the product. The extract disclosed by the invention has the effects of moisturizing, resisting wrinkles, delaying senescence andenhancing the skin immune function when being applied to cosmetics, and has a wide market prospect.

The invention discloses application of mannose glucuronic acid oligosaccharides and polysaccharides and derivatives in preparation of drugs for treating and / or preventing aging, and aims to solve problems of great side effects and general effects of existing anti-aging drugs. The mannose glucuronic acid oligosaccharides and polysaccharides and derivatives have a remarkable anti-aging effect, is small in toxic and side effects, safe and effective, and can be used for preparing anti-aging medicines. A preparation process is simple, yield is high, and source is safe.

The invention discloses a facial mask with an anti-aging effect. The facial mask is composed of a component A and a facial mask substrate component B, wherein the component A is prepared from the following raw materials in parts by weight: 4 to 10 parts of ginseng flower buds, 12 to 14 parts of natto, 1 to 3 parts of honey, 1 to 6 parts of stem cell exosome, 0.01 to 0.03 part of phenoxyethanol and 0.2 to 0.4 part of rape pollen. The composition provided by the invention is easier to absorb by skin and has a remarkable skin anti-aging effect. The ginseng flower has the effects of removing free radicals from the body, resisting oxidation and delaying senescence, meanwhile, the honey has good anti-oxidation, anti-inflammation and moisturizing effects, the beneficial components are freeze-dried and stored, the shelf life of the honey can be prolonged under the condition that no preservative is added, and the honey is mixed with the component B in use, so that the effects of maintaining beauty, keeping young and resisting aging are achieved through the synergistic effect.

The invention relates to an extraction technology of a moringa flavonoid glycosides compound and an application thereof in a neck mask, and belongs to the technical field of the plant chemistry and cosmetics. The extraction technology comprises the following steps: extracting a water-soluble extract from a moringa ethanol extract, separating and purifying by using a medium-pressure reverse phase silicagel column chromatography, a SephadexLH-20 gel column chromatography, and a semi-preparation high performance liquid chromatography successively. The moringa flavonoid glycosides compound as shown in a formula (I) is obtained. The compound has good anti-aging, anti-oxidant and anti-inflammation functions. The compound is used in the neck mask, and compounded with substances of moringa seed oil, sodium hyaluronate and the like, has the remarkable moisture-preserving, repairing, anti-inflammatory and anti-aging effects to neck skin, is capable of apparently improving a neck skin type, wherein the skin is fine, delicate and glossy, and apparently reducing wrinkles, and has the good treatment effect to neck acne and the like, wherein while a small wound is caused by acne extrusion, neck mask liquid of the invention can also be used, so the compound is wider in application range.

The invention provides a novel superoxide dismutase mutant, and the mutant shows the purposes of improving skin aging and reducing wrinkles, and has a wide application prospect. Furthermore, the invention also provides a transdermal total absorption type anti-aging nano functional mask containing the mutant.

The invention relates to an extraction technology of an anti-aging composition enabling a nerve cell to have nutrition. The technology comprises steps of coarse grinding on dry pigeon pea leaf and fresh rehmannia root, subcritical extraction, DM21 treatment, macroporous resin adsorption, vacuum concentration and composition preparation, and extracts a trophic nerve cell anti-aging composition, andhas the advantages that the source of feed is wide, the cost is low, the extraction technology is simple, the nerve cell has nutrition and the anti-aging effect is obvious.

The invention provides an application of plant juice for increasing the expression quantity of anti-aging genes and / or increasing the content of GSH (glutathione), the anti-aging activity and / or antioxidant activity can be comprehensively improved, and the user can be promoted to reverse to a young and active state. The plant juice is composed of saussurea involucrata juice, longan shell juice, buckwheat juice and any combination of the saussurea involucrata juice, the longan shell juice and the buckwheat juice.

The invention provides a food or functional food composition which is a food prepared by using eucommia ulmoides male flower extract liquor and walnut juice as active ingredients and adding auxiliarymaterials or auxiliary ingredients acceptable in food. The eucommia ulmoides male flower walnut milk is good in mouthfeel, high in quality and rich in nutrition, has a milk white or pale yellow colorand has the natural taste and smell of walnuts without objectional odors, the liquid is uniform without curds or foreign impurities visible to the naked eyes, the quality index meets standards, and the protein content is high; the eucommia ulmoides male flower walnut milk has multiple effects such as the significant antihypertensive effect and the anti-aging effect, can build the body and improvethe anti-stress ability, and also can tonify the brain and improve the learning ability and the memory ability. On the basis of having a good mouthfeel, the eucommia ulmoides male flower walnut milk overcomes the defect of single effect of existing walnut drinks and has strong estimated market competitiveness.

The invention discloses an anti-aging composition containing dihydromyricetin and application of the anti-aging composition. The anti-aging composition comprises dihydromyricetin, rosmarinic acid and puerarin. The application refers to the application of the anti-aging composition in preparation of anti-aging health care products. According to the anti-aging composition disclosed by the invention, the dihydromyricetin, the rosmarinic acid and the puerarin are selected as raw materials, so that the anti-aging composition is clear in functional components, small in toxic and side effects and good in safety, and potential safety hazards and risks caused by uncertain components of a traditional Chinese medicine compound are avoided. Meanwhile, it is found that by compounding dihydromyricetin, rosmarinic acid and puerarin, the anti-aging effect of dihydromyricetin can be remarkably improved, and the synergistic interaction effect is achieved.