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Extraction technology of anti-aging composition enabling nerve cell to have nutrition

A technology of nerve cells and extraction process, which is applied in the direction of drug combination, nervous system diseases, anti-toxins, etc., can solve the problems of ignoring mechanism research, etc., and achieve the effect of wide source of raw materials, significant anti-aging, and high extraction rate

Inactive Publication Date: 2018-06-01
THE CHINESE TRADITIONAL HERB MEDICINE RES INST HENAN PROV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The research on the mechanism of pigeon pea leaf tonifying the kidney was not carried out under the guidance of the theory of traditional Chinese medicine, ignoring the research on the mechanism of pigeonpea leaf tonifying the kidney and the kidney "generating marrow" in the theory of traditional Chinese medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] An extraction process for nourishing nerve cells and an anti-aging composition, the extraction process comprises the following steps:

[0029] Step 1: material selection: select dried pigeonpea leaves and freshly washed fresh rehmannia glutinosa, and 100kg of pigeonpea leaves and 500kg of fresh rehmannia;

[0030] Step 2: Coarse powder: Put the pigeonpea leaves obtained in step 1 into a pulverizer to pulverize, and the pulverized particles are 30 mesh in particle size;

[0031] Step 3: Subcritical extraction: put the coarse powder particles obtained in step 2 into 120°C for 30 minutes, repeat 3 times, collect the extract, precipitate at normal temperature and pressure, and recycle the collected solvent after pressurization. Take about 1 kg, dissolved in 5 kg of 95% ethanol;

[0032] Step 4: Process DM21: Take 4% sodium hydroxide solution, 4% hydrochloric acid solution, and ethanol that are twice the volume of DM21 and process them alternately in sequence;

[0033] Ste...

Embodiment 2

[0045] An extraction process for nourishing nerve cells and an anti-aging composition, the extraction process comprises the following steps:

[0046] Step 1: Material selection: select dried pigeonpea leaves and freshly washed fresh rehmannia glutinosa, and 50kg of pigeonpea and 250kg of fresh rehmannia;

[0047] Step 2: Coarse powder: Put the pigeonpea leaves obtained in step 1 into a pulverizer to pulverize, and the pulverized particles are 60 mesh in particle size;

[0048] Step 3: Subcritical extraction: put the coarse powder particles obtained in step 2 into 120°C for 30 minutes, repeat 3 times, collect the extract, precipitate at normal temperature and pressure, and recycle the collected solvent after pressurization. Take about 0.5 kg, dissolved in 2.5 kg of 95% ethanol;

[0049] Step 4: Process DM21: respectively take 4% sodium hydroxide solution, 4% hydrochloric acid solution, and ethanol that are twice the volume of DM21 and process them alternately in sequence;

[...

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Abstract

The invention relates to an extraction technology of an anti-aging composition enabling a nerve cell to have nutrition. The technology comprises steps of coarse grinding on dry pigeon pea leaf and fresh rehmannia root, subcritical extraction, DM21 treatment, macroporous resin adsorption, vacuum concentration and composition preparation, and extracts a trophic nerve cell anti-aging composition, andhas the advantages that the source of feed is wide, the cost is low, the extraction technology is simple, the nerve cell has nutrition and the anti-aging effect is obvious.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and specifically relates to a composition and an extraction process, in particular to an extraction process of a nutritional nerve cell and anti-aging composition. Background technique [0002] Aging is a continuous process of change. The international mainstream believes that free radicals damage human cells, causing many diseases and accelerating human aging. From generation to quenching, free radicals profoundly affect the formation of lipofuscin, mutation of mitochondrial DNA, induction of apoptosis and protein synthesis, thereby affecting the aging process. Free radicals can cause a variety of diseases, and scavenging free radicals can delay the aging process, which provides a certain scientific basis for humans to slow down their own aging. [0003] Modern studies have shown that nerve cell protection is an important mechanism for the prevention and treatment of neurodegenerative diseases...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/48A61P39/06A61P25/00A61P25/28A61P25/24A61P25/16A61P9/10
CPCA61K9/1652A61K36/48A61K36/804A61K2236/37A61K2236/55A61K2300/00
Inventor 刘长河李华妮王艳艳李开言张雪侠王晓丽周红艳胡雨菲郭荣华
Owner THE CHINESE TRADITIONAL HERB MEDICINE RES INST HENAN PROV
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