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A kind of preparation method of medical adhesive tape

A technology of adhesive tape and polycarbonate, applied in the directions of pharmaceutical formulation, application, medical science, etc., can solve the problem of secondary wound injury, and achieve the effect of preventing wound infection, promoting wound healing, and good effect.

Active Publication Date: 2021-07-02
安徽省六麦新材料科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] In the course of daily life and work, various emergencies often lead to bleeding in parts of the body. The current method of hemostasis usually uses medical gauze or cotton to press the bleeding point, and after a period of coagulation, then Remove the gauze or cotton; in addition, within a period of time after some local micro-trauma operations, the patient’s family members need to press the surgical wound for a long time to prevent wound bleeding. Secondary damage caused by the wound

Method used

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  • A kind of preparation method of medical adhesive tape
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The present embodiment provides a kind of preparation method of medical adhesive tape, comprises the following steps:

[0028] S1 Dimethicone surface biochemical treatment: Add 0.2 parts of nisin to a mixed solution consisting of 1 to 10 parts of polyhydroxyethylmethicate and 23 parts of dimethylsiloxane, and stir at high speed Mix it evenly to obtain dimethylsiloxane with surface biochemical treatment;

[0029] S2 aliphatic polycarbonate modification treatment: 1.2 parts of polyquaternium 31 and 0.5 part of polycarbonate-polyvinyl alcohol copolymer are added to 30 parts of aliphatic polycarbonate, the molecular weight of the aliphatic polycarbonate 5000, after heating to a molten state, perform high-speed stirring to make it evenly mixed, then add 0.8 parts of gelatin, and continue stirring for 1 hour to obtain polyquaternium modified aliphatic polycarbonate;

[0030] Preparation of S3 adhesive: 1.2 parts of dibutyltin oxide, 0.5 parts of polycarbonate grafted with ma...

Embodiment 2

[0033] The present embodiment provides a kind of preparation method of medical adhesive tape, comprises the following steps:

[0034] S1 Dimethylsiloxane surface biochemical treatment: Dissolve 2.1 parts of rubberin in dilute hydrochloric acid with pH = 3, after autoclaving at 121°C for 15 minutes, add to 4.5 parts of polyhydroxyethyl methate In a mixed solution composed of 46 parts of dimethylsiloxane, stir at a high speed to make it evenly mixed to obtain surface biochemically treated dimethylsiloxane;

[0035] S2 modification of aliphatic polycarbonate: add 1.9 parts of polyquaternium 33 and 2.5 parts of polyvinyl alcohol to 40 parts of aliphatic polycarbonate, the molecular weight of the aliphatic polycarbonate is 6000, heat to melt After the state, carry out high-speed stirring to make it mix evenly, then add 2.5 parts of gelatin, after continuing to stir for 1h, obtain polyquaternium modified aliphatic polycarbonate;

[0036] Preparation of S3 adhesive: 2.0 parts of dib...

Embodiment 3

[0039] The present embodiment provides a kind of preparation method of medical adhesive tape, comprises the following steps:

[0040] S1 Dimethicone surface biochemical treatment: Add 3.6 parts of natamycin to a mixed solution consisting of 10 parts of polyhydroxyethyl methate and 68 parts of dimethylsiloxane, and stir at a high speed to make it Mix evenly to obtain surface biochemically treated dimethylsiloxane;

[0041] S2 modification of aliphatic polycarbonate: 2.7 parts of polyquaternium 46 and 4 parts of polyethylene-polyvinyl alcohol copolymer are added to 50 parts of aliphatic polycarbonate, the molecular weight of said aliphatic polycarbonate is 8000, after heating to a molten state, perform high-speed stirring to make it evenly mixed, then add 5 parts of gelatin, and continue stirring for 1 hour to obtain polyquaternium modified aliphatic polycarbonate;

[0042]Preparation of S3 adhesive: 3.5 parts of dibutyltin dichloride, 0.6 parts of polycarbonate grafted maleic ...

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Abstract

A preparation method of medical adhesive tape, S1 is obtained by mixing a biological treatment agent with dimethylsiloxane to obtain surface biochemically treated dimethylsiloxane; S2 is obtained by adding polyquaternary ammonium salt to aliphatic polycarbonate Add gelatin to the ester resin to obtain polyquaternium modified aliphatic polycarbonate; S3 then add initiator, toughener, biochemically treated dimethylsiloxane and polyquaternium modified aliphatic The polycarbonate is put into the reaction kettle to carry out the copolymerization reaction, and is coated on the base material by an extrusion coating machine; S4 carries out the coating processing operation of the release film to obtain the medical adhesive tape. The medical adhesive tape of the present invention can effectively stop bleeding, absorb exudate, promote wound healing, prevent wound infection, and has good adhesive performance. The characteristics of toxic side effects.

Description

technical field [0001] The invention relates to the technical field of adhesive tapes, in particular to a preparation method of medical adhesive tapes. Background technique [0002] In the course of daily life and work, various emergencies often lead to bleeding in parts of the body. The current method of hemostasis usually uses medical gauze or cotton to press the bleeding point, and after a period of coagulation, then Remove the gauze or cotton; in addition, within a period of time after some local micro-trauma operations, the patient’s family members need to press the surgical wound for a long time to prevent wound bleeding. Causes secondary damage from the wound. [0003] Adhesive methods can effectively prevent secondary bleeding from wounds, and the most common adhesive products currently used for wound hemostasis are band-aids. It is actually an adhesive with a backing, but bleeding and trauma are accompanied together. Therefore, there is a clinical need for an adhe...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L24/04A61L24/00
CPCA61L24/001A61L24/0015A61L24/046A61L2300/252A61L2400/04C08L69/00C08L83/10
Inventor 王旭辉陈嘉辉潘炜邱仕凯
Owner 安徽省六麦新材料科技有限公司
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