A magnetic liquid droplet experimental chip for precise control of droplet fusion
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A technology of magnetic liquid and control liquid, which is applied in laboratory equipment, laboratory containers, chemical/physical/physicochemical processes, etc., and can solve problems such as inaccurate control
Active Publication Date: 2020-04-17
BEIJING JIAOTONG UNIV
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[0005] The technical problem to be solved in the present invention: the existing experimental chip cannot precisely control the motion trajectory of two specific droplets distributed in space and achieve precise and controllable fusion
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[0016] to attach figure 1 The present invention will be further described for the specific embodiment:
[0017] A magnetic liquid droplet experimental chip for precise control of droplet fusion, the experimental chip includes: continuous phase solution 1, first Y-shaped channel 2, second Y-shaped channel 3, third Y-shaped channel 4, to be tested Solution 5-1, first magnetic liquid 5-2, detection solution 6-1, second magnetic liquid 6-2, first composite droplet 7, second composite droplet 8, T-shaped channel 9, control coil 10, Fusion chamber 11, first cross channel 12, first reaction chamber 13-1, second reaction chamber 13-2, third reaction chamber 13-3, fourth reaction chamber 13-4, second cross Channel 14 , first electromagnetic coil 15 - 1 , second electromagnetic coil 15 - 2 , first iron core 16 - 1 , second iron core 16 - 2 , microblade 17 , product channel 18 .
[0018] Connections between the various parts of the experimental chip:
[0019] The first Y-shaped channe...
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Abstract
A magnetic liquid drop experimental chip for accurately controlling liquid drop fusion is suitable for measurement and analysis of a rare biomaterial. The experimental chip comprises a continuous phase solution (1), a first Y-type channel (2), a second Y-type channel (3), a third Y-type channel (4), a solution to be measured (5-1), a first magnetic liquid (5-2), a detection solution (6-1), a second magnetic liquid (6-2), a first composite liquid drop (7), a second composite liquid drop (8), a T-type channel (9), a control coil (10), a fusion chamber (11), a first cross-shaped channel (12), a first reaction chamber (13-1), a second reaction chamber (13-2), a third reaction chamber (13-3), a fourth reaction chamber (13-4), a second cross-shaped channel (14), a first solenoid coil (15-1), a second solenoid coil (15-2), a first iron core (16-1), a second iron core (16-2), a miniature blade (17) and a product channel (18). The magnetic liquid drop experimental chip is used for accurately controlling motion and fusion of liquid drops.
Description
technical field [0001] The invention belongs to the field of biological testing and is suitable for measuring and analyzing rare biological samples. Background technique [0002] At present, with the development of biological testing technology, higher requirements are put forward for the precision, speed and accuracy of testing. Traditional biological tests often titrate the powder of biological samples or the solution prepared by dissolving them with related solutions in a test tube to produce a chemical reaction, and then determine the composition of the biological samples. [0003] However, many biological samples are extremely rare, and the macroscopic titration method consumes too much biological samples, so it is not allowed to use this method for measurement and analysis, thus the concept of the experimental chip was proposed. Domestic research on experimental chips is still in its infancy, such as the patent "Lab on a Chip for Alkalinity Analysis" (patent applicati...
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