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Automated cell processing systems and methods

A shell and robot technology, applied in the field of cell processing of automated systems, can solve the problem that the system is not fully automated, and achieve the effect of effective processing, high processing efficiency and quality

Pending Publication Date: 2019-04-19
GENESIS TECH LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this system is not fully automated and has many of the limitations of the other systems mentioned above

Method used

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  • Automated cell processing systems and methods
  • Automated cell processing systems and methods
  • Automated cell processing systems and methods

Examples

Experimental program
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Embodiment

[0324] The present technology will be more readily understood by reference to the following examples, which are provided for the purpose of illustrating the invention and should not be construed as limiting the scope of the invention in any way.

[0325] Unless otherwise defined or clearly dictated by context, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. It should be understood that any methods and materials similar or equivalent to those described herein can be used in the practice or testing of the present invention.

Embodiment A

[0327] I. Introduction of samples.

[0328] step 1. The transfer tray 322 is to store biological samples (batches) (e.g., cell samples, tissue samples, biological samples (e.g., protein or antibodies) or other samples) are transferred from the isolator 120 to the housing 110. The container holders 410 are transferred by the robot module 700 from the transfer tray 322 to a predetermined location on the deck 910 (or into the storage area 300 until ready to be transferred on the deck 910).

[0329] The rest of the description uses cell or tissue samples (two days are required between medium replacement with fresh medium during culture) as batches and is for illustration purposes only. From reading the following description and throughout the remainder of this application, one of skill in the art will understand how the system processes biological, chemical or other samples.

[0330] II. Sample Preparation.

[0331] step2. The robotic decapper 830 opens the sample container a...

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Abstract

There are provided systems and methods for automated cell processing of biological samples, such as cells for use in cell therapy and regenerative medicine. Systems for automated processing of batchesderived from biological samples comprise: a closed and sterile enclosure; a plurality of reagent containers; at least one reagent dispenser; a quality control module for analyzing at least one characteristic of a batch; a harvesting module; a robotic module; and a control unit (CU) communicatively coupled to the at least one reagent dispenser, the quality control module, the harvesting module andthe robotic module for controlling the automatic processing of batches. The automatic processing may be executable without handling by a human operator. The system may be configured to automaticallyprocess the plurality of batches without cross-contamination between batches, e.g., under GMP conditions.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to U.S. Provisional Patent Application No. 63 / 352,468, filed June 20, 2016, the entire contents of which are incorporated herein by reference. technical field [0003] The present disclosure relates to the field of cell processing employing automated systems, and more particularly, to devices and methods for processing cells and other biological samples for cell therapy and regenerative medicine. Background technique [0004] Stem cell therapy holds great promise for regenerative medicine. Stem cells have the potential to develop into many different cell types in the body and can theoretically divide indefinitely to replenish cells in need of repair. There are different types of stem cells with different ranges of options for commitment. Embryonic stem cells hold great potential for regenerative medicine, however, they have a number of disadvantages, including the possibility of trans...

Claims

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Application Information

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IPC IPC(8): G01N35/00B01L1/02B01L1/04G01N35/10
CPCB01L1/02B01L1/04G01N35/00G01N35/0099G01N35/1002B01L2300/14G01N2035/00277G01N2035/00306G01N2035/1051B01L2300/06
Inventor 扬-埃里克·阿尔福斯
Owner GENESIS TECH LTD
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