Soluble hemostatic gauze for diminishing swelling, resisting bacteria and relieving pain

Abstract

The invention discloses a soluble hemostatic gauze for diminishing swelling, resisting bacteria and relieving pain, and belongs to the technical field of a macromolecular material. The soluble hemostatic gauze is prepared from the following raw materials including L-glutamic acid-gamma-ethyl ester, turpentine, Epsilon-caprolactone, 1,8-diazabicyclo [5.4.0] undecane-7-alkene, 1.3 to 2.7 parts of N-(tertbutyloxycarbonyl) neovaricaine, konjac glucomannan, trifluoroacetic acid, trichloromethyl carbonate, acetic hydrobromate solution, tetrahydrofuran, dichloromethane, xylene and traditional Chinesemedicine extracts. The soluble hemostatic gauze can form a gel state substance after being in contact with blood, so that the soluble hemostatic gauze can be well pasted in the wound position for fast stopping bleeding, preventing adhesion and realizing absorption in the body, and uses good tissue compatible hemostatic materials. The soluble hemostatic gauze uses the antibacterial medicine. In the use process, the adhesion of the gauze fiber to the wound can be avoided; the fast healing of the wound position can be promoted; the multiplex excellent effects of stopping bleeding, protecting thewound, resisting bacteria and relieving pain can be achieved.

Description

technical field [0001] The invention relates to the technical field of medical polymer materials, in particular to a soluble hemostatic gauze for reducing swelling, antibacterial and analgesic. Background technique [0002] Using medical gauze to wrap the wound is the most common and conventional method of hemostasis. The mechanism is that the gauze absorbs the water in the blood, concentrates blood cells and coagulation factors, and promotes blood coagulation. However, the problem of excessive blood absorption by traditional medical gauze has been ignored for a long time, which often leads to excessive wound bleeding, and in severe cases, patients will still die due to excessive blood loss. Traditional medical gauze uses pressure to compress the blood vessels of the wound when bandaging the wound, so that the blood flow rate of the wound will be slowed down, but the traditional gauze will absorb a large amount of blood. The main defects of partially absorbable hemostatic g...

AI Technical Summary

Problems solved by technology

The main defects of partially absorbable hemostatic gauze due to substandard quality and performance include: incomplete absorption, allergic reaction, rejection reaction, wound infection, compression of nerves and blood vessels (local retention and swelling can produce compression effects, such as paralysis, pain, etc.), Hoarseness caused by nerve adhesion (thyroid surgery), upper extremity edema caused by blood vessel adhesion (breast surgery), nerve damage and mucosal irritation caused by low pH, the body's blood coagulation mechanism is affected and does not function, etc., because absorbable hemostatic gauze Its physical properties swell after absorbing blood. If the excess material is not removed after achieving hemostasis, it will oppress peripheral nerves or tissues; material, production environment, production process; patient's own constitution; gauze placement site; surgical environment and aseptic technique, etc.

However, this soluble hemostatic gauze has poor antibacterial and disinfection functions and cannot solve the problem of postoperative adhesions

[0004] However, the combination of the drug and the soluble hemostatic gauze is not very stable and balanced, and the drug is not attached to the soluble hemostatic gauze with the best molecular structure, so that the effect of disinfection and sterilization is not fully exerted

[0005] In addition, external application of analgesic drugs may have adverse effects on wound healing. Therefore, the prior art generally uses oral or injected analgesic drugs. Analgesic drugs paralyze peripheral nerves, so that the human body cannot respond to wound information in time, affecting wound repair

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