Integrated apparatus for diagnostic analyses
An integrated equipment, diagnostic technology, applied in analytical materials, biochemical equipment and methods, and microbial determination/inspection, etc., can solve problems such as aggravation of infection and inability to completely eradicate bacterial colonies.
Inactive Publication Date: 2019-04-26
ALIFAX
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Problems solved by technology
In fact, although initially effective in inhibiting bacterial growth, the use of these broad-spectrum antibiotics creates disadvantages that not only may not completely eradicate all bacterial colonies, but also that surviving bacteria may become resistant to selected antibiotics through genetic mutations. resistance, followed by proliferation and exacerbation of infection
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[0047] We will now refer in detail to various embodiments of the invention, one or more of which are illustrated in the accompanying drawings. Each example is presented by way of explanation of the invention, and should not be construed as limiting the invention. For example, features shown or described as part of one embodiment can be used in or connected with other embodiments to yield yet another embodiment. It is to be understood that the present invention shall include all such modifications and variations.
[0048] Before describing these embodiments, we must also state that this specification is not limited in application to the details of construction and arrangement of the parts depicted in the drawings. The description may provide other embodiments and be carried out or be carried out in various other ways. We must also clarify that the phraseology and terminology used herein are for descriptive purposes only and should not be considered limiting.
[0049] Referri...
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Integrated apparatus for diagnostic analyses, comprising a support structure (11) inside which are positioned a first refrigerated container (26) to house at least one panel of antibiotics (n) contained in ampoules or phials (27), reconstituted with liquid to allow them to be dispensed in a liquid phase, and to be tested according to a plurality of molecules which can be selected by an operator and possibly also according to a plurality of concentrations (m), in order to carry out a modulatable antibiogram and MIC (Minimal Inhibitory Concentration) tests for each antibiotic chosen; an analysisarea (32) in which a plurality of microplates (35) is positioned with a plurality of receptacles or wells (36) in which a portion of a primary sample is inserted; a samples removal and delivery unit(20) configured to remove a portion of a primary sample from respective test tubes (13) and deliver it into the wells (36) of the microplates (35); a temperature control area (30) of the microplates (35) containing the primary samples; and a robotic head (14) configured to interact with the samples removal and delivery unit (20) so as to transfer the primary samples taken from the test tubes (13)in the microplates (35) of the analysis area (32) and to transfer the microplates (35) to the temperature control area (30) and configured to insert, into each of the wells (36) of the microplates (35), the sample where a bacterial growth has been identified, a portion of one of the antibiotics (n) in liquid form according to a choice at the discretion of the operator directed as a function of thetype of species identified.
Description
technical field [0001] The present invention relates to an integrated device for the diagnostic analysis of natural or obtained biological samples. The present invention is used to verify the presence of one or more bacteria in a sample to classify or identify the type of bacteria in order to select the appropriate antibiotic for treatment which is then analyzed for effectiveness along with the identified bacteria verification and in any case provides an automatic bacteriological analysis process without manual intervention by the operator starting from taking the sample into the urine collection container, test tube, various containers or other. [0002] The biological sample or primary biological sample to be analyzed can be, for example, urine, or other sterile and non-sterile human biological fluids. The automated steps of the analytical procedure are provided with: bacterial growth in liquid Egger medium, identification of bacterial species passing biochemical tests, aut...
Claims
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IPC IPC(8): G01N35/00G01N35/02G01N35/10G01N35/04
CPCG01N35/0099G01N35/028G01N35/109G01N2035/00356G01N2035/00435G01N2035/042G01N2035/1051G01N35/00C12Q1/18G01N35/1004
Inventor 保罗·加利亚诺
Owner ALIFAX