Transcutaneous electrical nerve stimulation using novel unbalanced biphasic waveform and novel electrode arrangement
A neurostimulation, biphasic technology, used in electrotherapy, therapy, etc., to solve problems such as suboptimal battery life
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[0045] General TENS
[0046] Transcutaneous electrical nerve stimulation (typically, abbreviated TENS) is the delivery of electricity across the entire surface of the skin in order to activate underlying nerves, generally with the goal of pain relief. Melzack and Wall in 1965 proposed a conceptual model of how stimulation of peripheral nerves elicits pain relief (Melzack R, Wall PD. Pain mechanisms: a new theory. Science. 1965 Nov 19;150(699):971-979 ). They theorized that activation of sensory nerves (Aβ fibers) closed the "pain gate" in the spinal cord, which inhibited the transmission of pain signals carried by nociceptive afferent nerves (C and Aδ fibers) to the brain. Over the past 20 years, the anatomical pathways and molecular mechanisms that may underlie the pain gate have been elucidated. Sensory nerve stimulation activates the descending pain-inhibitory system, primarily the periaqueductal gray (PAG) and rostroventral medial medulla (RVM) located in the midbrain ...
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