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An informatization structure and method for titer detection based on enzyme activity assay

A technology of enzyme activity and potency, which is applied in the field of information structure of titer detection, can solve the problems of fluctuating data detection, failure to identify interference data in time, etc., achieve simple structure, reduce deviation probability, and improve inspection efficiency

Active Publication Date: 2021-04-27
SPH NO 1 BIOCHEM & PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The informatization method adopts the automatic reading method of the ultraviolet-visible spectrophotometer. Since the automatic reading of the instrument cannot identify the interference data in time, the absorbance value read during the enzyme reaction has a certain probability of fluctuation, and the fluctuation data will bring great impact to the detection. immeasurable impact

Method used

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Embodiment Construction

[0021] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the specific embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them.

[0022] An informatization structure and method for titer detection based on enzyme activity assay, including a UV-visible spectrophotometer kinetic detection system and a laboratory information management system (LIMS), the UV-visible spectrophotometer kinetic detection system provides Raw data collection and raw data storage records, and provide raw data reports, the laboratory information management system (LIMS) captures the test data provided by the raw data reports, saves the original maps, and obtains the detection results, the UV-visible spectrophotometer The meter kinetic detection system includes a UV-visible spectrophotometer and a UV-visible spectrophotometer c...

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Abstract

The invention discloses an informatization structure and method of potency detection based on enzyme activity assay, including a dynamic detection system of a UV-visible spectrophotometer and a laboratory information management system (LIMS). The medical detection system provides raw data collection and raw data storage records, and provides raw data reports, and the laboratory information management system (LIMS) captures the test data provided by the raw data reports, saves the original maps, and obtains the detection results. The information structure and method of titer detection based on the enzyme activity assay has a simple structure and a high degree of intelligence, and adopts more scientific means for data analysis and processing, which can improve the inspection efficiency, reduce the probability of deviation, and ensure the integrity of the inspection data sex.

Description

technical field [0001] The invention relates to the technical field of potency determination of enzyme drugs, in particular to an information structure and method for potency detection based on enzyme activity assays. Background technique [0002] The laboratory information management system has brought new possibilities for drug testing. While effectively ensuring the integrity of laboratory data, it can also provide more efficient experimental modes and more accurate data processing conditions. Enzyme activity detection integrates the effects of constant temperature control, enzyme and substrate reaction, linear change of absorbance, and data linear fitting. The test takes a lot of time and the probability of deviation is high. At present, the test uses a stopwatch to time the time, and manually records the data at the corresponding time point. After obtaining the original data, the potency result is obtained through simple analysis. This method has high requirements for ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G16C20/90G01N21/31
CPCG01N21/31G16C20/90
Inventor 郝士婧朱敏莹常超
Owner SPH NO 1 BIOCHEM & PHARMA CO LTD