A kind of method utilizing palladium-catalyzed homogeneous allyl substitution reaction to synthesize polysulfone
An allyl-substituted, palladium-catalyzed technology, applied in the field of synthesis of polysulfone, can solve the problems of poor thermal stability of alkyl polysulfone, etc., and achieve the effects of high yield, simple operation and mild conditions
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Embodiment 1
[0012] Embodiment 1: Synthesis of 1-4 diethyl benzene diacrylate 3a
[0013]
[0014] Weigh 2.4g of sodium hydride directly into a 500mL dry round-bottomed flask, use a large stirring magnet, pump the argon for 15min under the protection of argon, add 200mL of anhydrous tetrahydrofuran under argon, stir for ten minutes, and then put the reaction Place the bottle in an ice-water bath, under argon, slowly add 10 mL of triethyl phosphoroacetate, stir for 15 minutes, return the reaction to room temperature and stir for two hours, slowly add 2.68 g of terephthalaldehyde several times in small amounts In the reaction bottle, monitor the reaction by thin layer chromatography (TLC) until the raw materials disappear. After the reaction is completed, the reaction bottle is placed in an ice-water bath, and saturated ammonium chloride solution is slowly added until no bubbles are produced. After three extractions, the organic phases were combined, washed with saturated brine, dried ove...
Embodiment 2
[0015] Embodiment 2: Synthesis of 1-3 diethyl benzene diacrylate 3b
[0016]
[0017] Weigh 2.4g of sodium hydride directly into a 500mL dry round-bottomed flask, use a large stirring magnet, pump the argon for 15min under the protection of argon, add 200mL of anhydrous tetrahydrofuran under argon, stir for ten minutes, and then put the reaction Place the bottle in an ice-water bath, under argon, slowly add 10 mL of triethyl phosphoroacetate, stir for 15 minutes, return the reaction to room temperature and stir for two hours, slowly add 2.68 g of terephthalaldehyde several times in small amounts In the reaction bottle, the reaction is monitored by thin layer chromatography (TLC) until the raw materials disappear. After the reaction is completed, the reaction bottle is placed in an ice-water bath, and saturated ammonium chloride solution is slowly added until no bubbles are generated, and extracted three times with ethyl acetate. Finally, the organic phases were combined, wa...
Embodiment 3
[0018] Example 3: Synthesis of 4,4-oxydiphenyl diacrylate 3c
[0019]
[0020] Weigh 2.4g of sodium hydride directly into a 500mL dry round-bottomed flask, use a large stirring magnet, pump the argon for 15min under the protection of argon, add 200mL of anhydrous tetrahydrofuran under argon, stir for ten minutes, and then put the reaction Place the bottle in an ice-water bath, under argon, slowly add 10 mL of triethyl phosphoroacetate, stir for 15 minutes, return the reaction to room temperature and stir for two hours, add 4.52 g of p-diphenyl ether diformaldehyde in a small amount several times Slowly add in the reaction flask, monitor the reaction by thin layer chromatography (TLC) until the raw materials disappear, place the reaction flask in an ice-water bath after the reaction, slowly add saturated ammonium chloride solution until no bubbles are produced, and use ethyl acetate After three extractions, the organic phases were combined, washed with saturated brine, dried...
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