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System for the production of cells and/or cell products

A derivative product, cell technology, applied in laboratory containers, biochemical equipment and methods, methods of supporting/immobilizing microorganisms, etc., can solve the problems of high cost and high cost, and achieve low cost, low investment and production cost, effect of preventing environmental pollution

Inactive Publication Date: 2019-08-16
UNIVERCELLS SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These facilities are expensive and require extensive training for those involved, as well as the use of protective clothing and equipment
Take measures for existing facilities to prevent contamination of the external environment with cultured cells or viruses, resulting in very high cost expenditures

Method used

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  • System for the production of cells and/or cell products
  • System for the production of cells and/or cell products
  • System for the production of cells and/or cell products

Examples

Experimental program
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Embodiment Construction

[0018] The present invention relates to systems and methods for producing biological products. In particular, the present invention provides systems and methods for the production of cells, viruses, or cell- or virus-derived products. Cells, viruses, or cell or virus derived products are referred to herein as "products" or "end products".

[0019] Unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. By way of further guidance, definitions of terms are included for a better understanding of the teachings of the present invention.

[0020] As used herein, the following terms have the following meanings:

[0021] As used herein, "a", "an" and "the" refer to singular and plural referents unless the context clearly dictates otherwise. By way of example, "compartment" refers to one or more than one compartment.

[0022] As used h...

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PUM

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Abstract

The invention provides a method and a system for the production of viruses or virus derived products. The system comprises a containment enclosure provided with a single entry means and a single exitmeans which are movable between a closed position and an open position. The containment enclosure comprises at least one production unit comprising at least one bioreactor for culturing the virus, said bioreactor is provided with at least one inlet and at least one outlet; at least one purification unit fluidly connected to the production unit and comprising at least one purification means havingat least one inlet and at least one outlet. The system further comprises at least one inactivation and / or at least one gas decontamination unit. The containment enclosure comprises at least one process control device connected to the exit means. The movement of the exit means from the closed position to the open position is controllable by said process control device.

Description

technical field [0001] The present invention relates to systems and methods for contained and confined production of biological products. In particular, the invention relates to the production of cells, viruses or cell or virus derived products. Background technique [0002] Biopharmaceuticals and renewable chemicals (also referred to herein as "biologics") are a growing segment of the global biologics market. Known biologicals include, for example, veterinary pharmaceutical proteins, human proteins, animal proteins, vegetable proteins, pharmaceutical proteins, microbial biomass, viruses or viral particles. Biologics production is a highly regulated and technically complex process. The production has certain requirements on the production capacity of the bioreactor, and the production of biological products must meet the standards of good laboratory practice or good manufacturing practice. Biologics require more planning, investment, documentation, technical staff, and re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/12B01L1/04
CPCB01L1/04C12M37/00C12M37/02C12M41/12C12M41/48B01L3/502715B01L2300/06C12N7/00C12M23/52
Inventor J·卡斯蒂略B·迈雷斯
Owner UNIVERCELLS SA
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