Composition containing total gingerol and preparation method of composition

Abstract

The invention relates to a composition having effect of relieving pain. According to the composition, total gingerol is used as an active component, pharmaceutically acceptable auxiliary materials orauxiliary components are added, and a preparation is prepared, wherein the total content of 6-gingerol, 8-gingerol and 10-gingerol in the total gingerol is greater than 50%. The composition having theeffect of relieving pain is good in transdermal absorption effects, notable in medicine effects, convenient to use, and free from stimulation to stomach and intestines. A preparation method of the active component namely the total gingerol is simple in operation steps, the used raw materials are low in price, the obtained total gingerol is high in quality, and the total gingerol is free from special smell of fresh ginger, and is suitable for being used as an active component of an external preparation.

Description

technical field

[0001] The invention belongs to the field of medicinal chemistry, and in particular relates to a composition containing total gingerol and a preparation method thereof. Background technique

[0002] Rheumatoid arthritis (RA) is a chronic systemic disease with unknown etiology, mainly inflammatory synovitis. Its pathogenesis may be related to heredity, infection, sex hormones, etc. The pathology of RA arthritis mainly includes the proliferation of synovial lining cells, the infiltration of a large number of inflammatory cells in the interstitium, the neogenesis of microvessels, the formation of pannus, and the destruction of cartilage and bone tissue. Rheumatoid arthritis is a common acute or chronic inflammation of connective tissue. Commonly said rheumatoid arthritis is one of the main manifestations of rheumatic fever, clinically characterized by joint and muscle migratory soreness, redness and pain. It is related to group A beta-hemolytic streptococcal ...

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