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Traditional Chinese medicine composition for treating cerebral ischemia, preparation and application

A composition and a technology of cerebral ischemia, applied in the field of medicine, can solve the problems of side effects and poor therapeutic effect, and achieve the effects of reducing fishy smell, improving percolation efficiency, and facilitating administration

Inactive Publication Date: 2019-08-23
HEILONGJIANG UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the problem of poor therapeutic effects and side effects of existing drugs for promoting blood circulation and removing blood stasis, dredging meridians and activating collaterals, especially for sequelae of ischemic stroke, and to invent a traditional Chinese medicine composition for treating cerebral ischemia and its Preparation method, preparation

Method used

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  • Traditional Chinese medicine composition for treating cerebral ischemia, preparation and application
  • Traditional Chinese medicine composition for treating cerebral ischemia, preparation and application
  • Traditional Chinese medicine composition for treating cerebral ischemia, preparation and application

Examples

Experimental program
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Effect test

Embodiment 1

[0037] The traditional Chinese medicine composition is composed of the following traditional Chinese medicines in parts by weight: 10 parts of notoginseng, 20 parts of red ginseng, 5 parts of Chinese yam, 5 parts of hawthorn, 25 parts of Yuanhu, 15 parts of earthworm, 15 parts of 15 parts of scorpion, 15 parts of salvia, 20 parts of Chuanxiong, and 15 parts of safflower.

[0038] A preparation method of a traditional Chinese medicine composition for treating cerebral ischemia, comprising the following steps:

[0039] S01 Take 5 parts of dried hawthorn and 15 parts of safflower, crush them, and pass through a 120-mesh sieve to obtain raw material I, which is placed in a flash extractor and extracted with pure water for 3 times, and the weight of water added for each extraction is 10 times the total dry weight of raw material Ⅰ, add water to soak for 30 minutes before the first extraction, each extraction time is 10 minutes, set the rotation speed to 5500r / min, every rotation is...

Embodiment 2

[0098] A traditional Chinese medicine composition for treating cerebral ischemia. The traditional Chinese medicine composition is composed of the following traditional Chinese medicines in parts by weight: 20 parts of Panax notoginseng, 10 parts of red ginseng, 15 parts of Chinese yam, 15 parts of hawthorn, 25 parts of Yuanhu, 15 parts of earthworm, 5 parts of scorpion, 20 parts of salvia, 15 parts of Chuanxiong, and 10 parts of safflower.

[0099] A preparation method of a traditional Chinese medicine composition for treating cerebral ischemia, comprising the following steps:

[0100] S01 Take 15 parts of dried hawthorn and 10 parts of safflower, crush them, and pass through a 120-mesh sieve to obtain raw material I, which is placed in a flash extractor and extracted with pure water for 3 times, and the weight of water added for each extraction is 15 times the total dry weight of raw material Ⅰ, soak in water for 30 minutes before the first extraction, each extraction time is...

Embodiment 3

[0111] The traditional Chinese medicine composition is composed of the following traditional Chinese medicines in parts by weight: 25 parts of notoginseng, 10 parts of red ginseng, 15 parts of Chinese yam, 15 parts of hawthorn, 15 parts of Yuanhu, 5 parts of earthworm, 25 parts of 10 parts of Scorpion, 35 parts of Danshen, 10 parts of Chuanxiong, and 5 parts of Safflower.

[0112] A preparation method of a traditional Chinese medicine composition for treating cerebral ischemia, comprising the following steps:

[0113] S01 took 15 parts of dried hawthorn and 5 parts of safflower, crushed them, and passed through a 120-mesh sieve to obtain raw material I, which was placed in a flash extractor and extracted with pure water for 3 times, and the weight of water added for each extraction was 12 times the total dry weight of raw material Ⅰ, soak in water for 30 minutes before the first extraction, each extraction time is 10 minutes, set the number of revolutions to 5500r / min, each ro...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating cerebral ischemia. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials of 10 to 25 parts of radix notoginseng, 10 to 20 parts of Yunnan madder roots, 5 to 15 parts of rhizoma dioscoreae, 5 to 15 parts of fructus crataegi, 15 to 25 parts of rhizoma corydalis, 5 to 15 parts of earthworm, 5 to 25 parts of scorpion, 15 to 35 parts of radix salviae miltiorrhizae, 10 to 20 parts of rhizoma chuanxiong and 5 to 15 parts of safflowers. The invention also discloses a preparation method of the traditional Chinese medicine composition for treating cerebral ischemia, and a traditional Chinese medicine preparation containing the traditional Chinese medicine composition. Through being proved by pharmacological experiments, a cerebral ischemia treatment model is certainly effective; the composition can be used for the clinic application for treating the cerebral ischemia.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating cerebral ischemia and its preparation method, preparation and application, belonging to the field of medicine. Background technique [0002] Stroke, also known as stroke (Apopplery) or cerebrovascular accident (Cerebrovascular accident), is the most serious acute and cerebrovascular clinical system disease that threatens human life and affects the quality of life. It is characterized by clinical symptoms such as coma, slanted mouth and eyes, and limb discomfort, and has a high recurrence rate, disability rate, and mortality rate. Among them, ischemic stroke accounts for 75% of the total number of strokes. [0003] The traditional Chinese patent medicines commonly used in the market to treat stroke are mostly composed of blood-activating and stasis-removing drugs, such as Mailuoning Injection, Compound Danshen Injection, Danshen Injection, Ligustrazine Injection, Qingkaili...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P9/10A61K35/62A61K35/646
CPCA61K35/62A61K35/646A61K36/236A61K36/258A61K36/286A61K36/537A61K36/66A61K36/734A61K36/8945A61K2236/331A61K2236/333A61K2236/39A61K2236/55A61P9/10A61K2300/00
Inventor 董晓红王磊王悦阳付琳刘斌张正一姚壮
Owner HEILONGJIANG UNIV OF CHINESE MEDICINE