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Cavitation localization

A cavitation and reference signal technology, applied in the field of ultrasound systems, can solve a wide range of tissue damage, bleeding, cell death, etc., and achieve the effect of reducing time and complexity requirements

Active Publication Date: 2019-09-17
医视特有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at high acoustic pressures, unstable (or inertial) cavitation of microbubbles can be induced, and this can lead to undesired biological effects such as hemorrhage, cell death, and extensive tissue damage beyond the target

Method used

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  • Cavitation localization
  • Cavitation localization
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Examples

Experimental program
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Embodiment Construction

[0041] figure 1 An exemplary ultrasound system 100 is shown for focusing ultrasound through the cranium into a patient's brain. However, those of ordinary skill in the art will understand that the ultrasound system 100 described herein may be applied to any part of the human body. In various embodiments, the system 100 includes a phased array 102 of transducer elements 104, a beamformer 106 driving the phased array 102, a controller 108 in communication with the beamformer 106, and providing Input the frequency generator 110 of the electronic signal. In various embodiments, the system also includes an imager 112, such as a magnetic resonance imaging (MRI) device, a computed tomography (CT) device, a positron emission tomography (PET) device, a single photon emission computed tomography ( SPECT) equipment or ultrasound scanning equipment for determining the anatomical features of the skull 114 of the patient 116. Ultrasound system 100 and / or imager 112 may be used to detect ...

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Abstract

Various approaches for detecting microbubble cavitation resulting from ultrasound waves transmitted from an ultrasound transducer include associating at least one time-domain reference signal with microbubble cavitation; causing the transducer to transmit one or more ultrasound pulse; acquiring, in the time domain, an echo signal from microbubbles in response to the transmitted ultrasound pulse(s); correlating at least a portion of the echo signal to at least a corresponding portion of the time-domain reference signal based on similarity therebetween; and detecting the microbubble cavitation based on the corresponding portion of the reference signal.

Description

technical field [0001] The field of the invention relates generally to ultrasound systems, and more specifically, to systems and methods for detecting and locating cavitation caused by microbubbles during an ultrasound procedure. Background technique [0002] Focused ultrasound (ie, sound waves with a frequency greater than about 20 kilohertz) can be used to image or treat internal body tissue within a patient. For example, ultrasound can be used in applications involving the removal of tumors, eliminating the need for invasive procedures, targeted drug delivery, blood-brain barrier control, clot lysis, and other surgical procedures. During tumor resection, piezoceramic transducers are placed outside the patient, but in close proximity to the tissue to be resected (ie, the target). The transducer converts the electrical drive signal into mechanical vibration, which produces the emission of sound waves. The transducer may be geometrically configured and positioned with othe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B8/08A61B8/00
CPCA61B8/0808A61B8/085A61B8/4416A61B8/4488A61B8/481A61B8/5223A61B8/4494G16H50/30A61B8/14A61B8/08A61B8/54A61B8/5215A61B8/5292
Inventor O·普鲁斯约阿夫·利维
Owner 医视特有限公司