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Chinese medicinal granule for treating infantile cough and asthma and preparation method thereof

A technology of traditional Chinese medicine granules and children's cough and asthma, which is applied in medical formulas, medical preparations containing active ingredients, drug combinations, etc., can solve problems such as turbidity in solubility, soft hardness, and conflicting indicators, and achieve multiple properties Good effect in terms of control, multiple properties

Inactive Publication Date: 2019-10-01
HAINAN HAILI PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Solubility and hygroscopicity are two important quality control indicators of this granular drug. However, in the existing technical methods, it is often difficult to achieve satisfactory results for the control of these two parameters, and turbidity is prone to appear in terms of solubility. The problem is that the hardness is soft, or the two indicators conflict with each other and it is difficult to balance

Method used

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  • Chinese medicinal granule for treating infantile cough and asthma and preparation method thereof
  • Chinese medicinal granule for treating infantile cough and asthma and preparation method thereof
  • Chinese medicinal granule for treating infantile cough and asthma and preparation method thereof

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Experimental program
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Effect test

Embodiment 1

[0021] The prescription dosage of the Chinese medicine granules for the treatment of infantile cough and asthma of the present embodiment is shown in the following table (making 1000 bags):

[0022] components parts by weight ephedra 62.5 honeysuckle 625 Bitter almonds 312.5 Banlangen 625 plaster 937.5 licorice 312.5 Gualou 312.5 dextrin 257 sucrose 514

[0023] Such as figure 1 Shown, the preparation method of the Chinese medicine granule of the treatment infantile cough and asthma of the present embodiment, comprises the steps:

[0024] S1: Extraction step, take gypsum, bitter almond, licorice, isatid root and Trichosanthes five herbs, put them into a multi-functional extraction tank, add 10 times the amount of water, decoct for 1 hour, filter to obtain medicinal residues and the first a filtrate;

[0025] S2: proceed to the extraction step, then take the two medicinal materials of ephedra and honeysuckl...

Embodiment 2

[0029] The prescription dosage of the Chinese medicine granules for the treatment of infantile cough and asthma of the present embodiment is shown in the following table (making 1000 bags):

[0030]

[0031]

[0032] Such as figure 1 Shown, the preparation method of the Chinese medicine granule of the treatment infantile cough and asthma of the present embodiment, comprises the steps:

[0033] S1: Extraction step, take gypsum, bitter almond, licorice, isatid root and Trichosanthes five herbs, put them into a multi-functional extraction tank, add 10 times the amount of water, decoct for 1 hour, filter to obtain medicinal residues and the first a filtrate;

[0034] S2: proceed to the extraction step, then take the two medicinal materials of ephedra and honeysuckle, add them to the medicinal residues, add 9 times the amount of water, decoct for 1 hour, and filter to obtain the second filtrate;

[0035] S3: Mixing and making a thick paste step, mix the first filtrate and t...

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Abstract

The invention provides a Chinese medicinal granule for treating infantile cough and asthma and a preparation method thereof. The provided Chinese medicinal granule for treating infantile cough and asthma comprises 936.5-938.5 parts of gypsum, 312-313.5 parts of bitter almonds, 311.5-313 parts of radix glycyrrhizae, 623.5-626 parts of radix isatidis, 311-314 parts of fructus trichosanthis, 61-64 parts of radix etrhizoma ephedrae and 623-626 parts of flos lonicerae, dextrin and sucrose, wherein there are 255-260 parts by weight of the dextrin, and the weight ratio of the dextrin to the sucrose is 1:2. According to experimental analysis, the weight ratio of the dextrin to the sucrose is discussed; it is found that when the weight ratio of the dextrin to the sucrose is 1:2, the dissolvabilityis complete, an obtained solution is slightly turbid, the weight gain rate is 8.32%, the requirement is met, and the hardness is pretty high and meets the requirement. It can be seen that obtained drug particles under the weight ratio are well controlled.

Description

technical field [0001] The present invention relates to a processing method of traditional Chinese medicine components, in particular to a traditional Chinese medicine granule for treating infantile cough and asthma and a preparation method thereof. Background technique [0002] Pediatric cough can be divided into acute cough and chronic cough. It is a chronic airway inflammatory disease and is an immune inflammation. It is characterized by reversible airway narrowing and dyspnea. Its clinical manifestations are shortness of breath, Cough, phlegm, dyspnea, wheezing can be heard in the lungs, especially when exhaling, the wheezing sound can be relieved by anti-asthma drugs in children, and it can also be relieved by itself, and the most common relief with drugs The most popular one is Xiaoer Kechuanling Granules. The ingredients of the drug are mainly ephedra, honeysuckle, bitter almond, isatid root, gypsum, licorice, Trichosanthes, dextrin and sucrose. For cough caused by u...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61K9/16A61P11/14A61P11/06A61K33/06
CPCA61K9/1652A61K33/06A61K36/17A61K36/195A61K36/315A61K36/355A61K36/428A61K36/484A61K36/736A61K2236/331A61K2236/51A61K2236/53A61P11/06A61P11/14A61K2300/00
Inventor 余国新许丹青耿亮
Owner HAINAN HAILI PHARMACEUTICAL CO LTD