Electrostatic arch wire three-dimensional printed artificial intervertebral disc bracket and preparation method thereof

Abstract

The invention discloses an electrostatic arch wire three-dimensional printed artificial intervertebral disc bracket and a preparation method thereof. The electrostatic arch wire three-dimensional printed artificial intervertebral disc bracket is prepared from the following raw materials in parts by mass: 10-16 parts of chondrocyte, 3-6 parts of fetal calf serum, 8-10 parts of bone marrow stem cells, 7-9 parts of connective tissue growth factors, 5-6 parts of ascorbic acid, 7-9 parts of a biological material, 7-9 parts of an organic macromolecule material and 7-9 parts of a biological macromolecule material. The electrostatic arch wire three-dimensional printed artificial intervertebral disc bracket has the beneficial effects that properties such as a controllable porosity, a large specificsurface area, good biocompatibility and good mechanical properties achieved by printing wires which are mutually interwoven are achieved, according to demands, printing route parameters are designed,an artificial bionic intervertebral disc which is high in structure precision and controllable in mechanical property and meanwhile carries a great number of seed cells for multiplication repairing can be obtained, micro environments around the intervertebral disc can be rapidly established, and functions of the intervertebral disc can be recovered.

Description

technical field [0001] The invention relates to the technical field of electrospinning three-dimensional printing, in particular to an artificial intervertebral disc bracket with three-dimensional electrostatic filament printing and a preparation method thereof. Background technique [0002] The lumbar intervertebral disc is composed of three parts, the nucleus pulposus, the annulus fibrosus and the cartilage plate. It is located between the upper and lower vertebral bodies and plays a role in supporting rotation and reducing the friction coefficient during the movement of the lumbar spine. Lumbar disc herniation is a relatively common injury to the motor system, and its incidence is increasing year by year. The main cause is that after a certain degree of degenerative changes in the lumbar intervertebral disc, the annulus fibrosus is ruptured under the induction of external force, and the nucleus pulposus tissue compresses the tissue in the spinal canal, causing the adjacen...

AI Technical Summary

Problems solved by technology

The artificial intervertebral discs currently used clinically are mainly made of metal materials, and their disadvantages are that metal materials have poor lubrication and wear resistance.

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