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Liquid dispenser

A dispenser and liquid sensor technology, applied in liquid distribution, conveying or transfer devices, liquid materials, distribution devices, etc., can solve problems such as damage to chromatographic system components, sample loss, surface contamination of fraction collectors, etc.

Inactive Publication Date: 2019-11-22
BIO RAD LAB INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

During transport of dispensers or receivers, liquid may spill between receivers, resulting in loss of precious sample or contamination of adjoining receiver and / or fraction collector surfaces
Divert liquids to waste during transport of dispensers or receivers to prevent spillage, but can result in sample loss
Stopping liquid flow during dispenser or receiver movement can cause back pressure, which can damage components of the chromatography system

Method used

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  • Liquid dispenser
  • Liquid dispenser

Examples

Experimental program
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Embodiment Construction

[0015] Distributors for fraction collectors and methods of using such distributors are described herein. Dispensers and methods of use thereof have been discovered wherein liquid is dispensed during travel of the dispenser or receptacle without spilling, splashing or dripping liquid between fraction collector receptacles.

[0016] figure 1 An embodiment of a dispenser 100 for dispensing liquid is shown. Dispenser 100 may be used in a fraction collector configured to collect fractions of a liquid from a liquid source (eg, a liquid chromatography system). For the dispenser 100, liquid is received by an inlet 102 in fluid communication with an outlet 104 from which the liquid is dispensed into a receptacle (eg, a tube, microwell plate, vial, or bottle). The dispenser 100 is movable between a first receptacle and a second receptacle, or the receptacles are movable between dispensing locations.

[0017] Dispenser 100 also includes an accumulator 106 in fluid communication with a...

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PUM

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Abstract

Fraction collector dispensers and methods of using such dispensers are provided. In one embodiment, the dispenser includes an inlet for receiving liquid from a liquid source, wherein the inlet is in fluid communication with an outlet from which liquid is dispensed into a receptacle; and a reservoir in fluid communication with a flow path between the inlet and outlet, wherein the reservoir comprises trapped air therein and is configured to receive liquid during movement of the dispenser between receptacles or during movement of receptacles between dispense positions, wherein the dispenser is moveable between a first receptacle and a second receptacle or the receptacles are moveable between dispense positions.

Description

[0001] This application claims the benefit of U.S. Provisional Application No. 62 / 484,483, filed April 12, 2017, which is incorporated herein by reference in its entirety. Background technique [0002] Fraction collectors are commonly used to collect liquid fractions from liquid chromatography systems. Fraction collectors collect fractions from a continuous stream of liquid by using a dispenser to distribute the liquid into receptacles such as tubes, microplates, vials, or bottles. When a sufficient volume of liquid has collected in a receptacle, the dispenser is moved to the next receptacle or the next receptacle is moved to the dispensing position. During transport of the dispenser or receiver, liquid may spill between the receivers, resulting in loss of precious sample or contamination of adjoining receiver and / or fraction collector surfaces. Diverting liquids to waste during transport of dispensers or receivers prevents spillage, but can result in sample loss. Stopping l...

Claims

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Application Information

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IPC IPC(8): G01N1/18B67D7/02G01F11/28B65B3/30B01D15/24F04F1/06B01J4/02
CPCG01N30/82B01L3/0234B01L2200/0605B01L2200/0615B01L2300/14G01N35/1016G01N2035/1025G01N1/14G01N1/18
Inventor Y·乌里I·科切特科夫S·艾哈容I·巴拉克U·伊斯曼
Owner BIO RAD LAB INC