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Method for effectively promoting infiltration promotion of feature beautifying polypeptide

A technology for promoting penetration and whitening, which is used in pharmaceutical formulations, cosmetics, cosmetic preparations and other directions to achieve the effects of increasing content, wide adaptability and improving efficacy.

Pending Publication Date: 2019-12-20
浙江湃玥生物有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no report on the combined use of carbitol and piperine in beauty peptide products to promote transdermal absorption

Method used

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  • Method for effectively promoting infiltration promotion of feature beautifying polypeptide

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A: Prepare cosmetic peptide solution: carnosine 0.1%, glycerin 25%, 1,2 hexanediol 1%, ethylhexylglycerin 0.1%, water 70-80%, the initial peptide content is detected after configuration; B: Carbitol 1 %; C: Piperine at 0.01%, A, B and C are stirred and dissolved evenly, which is the sample for the supply pool.

Embodiment 2

[0026] Embodiment 2 is different from embodiment 1 in that: in C, piperine is 0.03%.

Embodiment 3

[0028] Embodiment 3 is different from embodiment 1 in that: in C, piperine is 0.05%.

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Abstract

The invention discloses a method for effectively promoting transdermal absorption of feature beautifying polypeptide. Carbitol (B) and piperine (C) are added to cosmetics containing the feature beautifying polypeptide (A), wherein the addition weight proportion range of the carbitol (B) to the piperine (C) is (50 to 1) to (10 to 1). The transdermal absorption of the feature beautifying polypeptidecan be effectively increased, the content of the feature beautifying polypeptide in a derma layer can be increased, the efficacy of the feature beautifying polypeptide applied to the cosmetics can beimproved, and expected effects of the feature beautifying polypeptide in the field of the efficacy of the cosmetics can be achieved.

Description

technical field [0001] The invention belongs to the field of cosmetics, in particular to a method for effectively promoting transdermal absorption of cosmetic polypeptides, and its medical application, especially the application of skin beauty. Background technique [0002] Cosmetic peptides are usually 2-10 amino acid condensates, with a molecular weight distribution of 300-1500. Compared with other active substances, they have a certain transdermal absorption due to their smaller molecular weight. However, cosmetic peptides are formed by linking amino groups through peptide bonds. , the number of different amino acids has a large difference in molecular weight. At the same time, due to the different types of amino acids, most of the peptides are highly hydrophilic and charged. The ordinary passive diffusion transdermal absorption rate cannot achieve the ideal transdermal effect and cannot be effective on the skin. Parts to achieve sufficient content to play its ideal effec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/34A61K8/49A61K8/64A61Q19/00A61Q19/02A61Q19/08
CPCA61K8/64A61K8/34A61K8/4973A61Q19/02A61Q19/08A61Q19/00A61Q19/005
Inventor 柯勇群
Owner 浙江湃玥生物有限公司