Oral care compositions and methods of use
A technology for oral care and composition, applied in the field of manufacturing and using these compositions, can solve the problems such as can not fully solve the problems of dry mouth and discomfort
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example 1
[0099] Example 1 - Measurement of Coefficient of Friction
[0100] The device used in these studies used the butterfly haptics Magnetic Levitation Haptic Device (MLHD) manufactured by Butterfly Haptics (Pittsburgh, PA) and custom-made haptics (see Yardley et al., Skin Research and Technology), 2016; 22:115-127). The MLHD is a six degrees of freedom (6-DOF) device that uses six Lorentz actuator coils to generate rotational and linear forces on a central assembly called a 'flotor'. In operation, the MLHD's buoyants are not in physical contact with the rest of the device, and therefore do not generate friction or recoil. The MLHD is capable of moving buoyancy devices with a spherical diameter of 24 mm, with a position resolution of 2000Hz.
[0101] Since the MLHD was not equipped with a force / torque transducer, the buoyancy device of the MLHD was modified to accept an ATINano-17 6-axis force / torque transducer (ATI Industrial Automation, Apex, NC). The sensor is fixed on two ar...
Embodiment 2
[0114] Example 2 - In vitro analysis of water retention capacity
[0115]A qualitative method was developed to evaluate and demonstrate the moisture retention capacity of mouthwash products. This method utilizes VitroSkin TM (IMS Inc., Portland, ME) as the model matrix. Vitro skin TM is an advanced test matrix that mimics the surface properties of human skin and contains protein and lipid components. Its morphology, pH, critical surface tension, and ionic strength are similar to those of human skin.
[0116] Briefly, punch out a Vitro skin with a diameter of 20mm TM slice and place it on a six-well plastic plate. Then add 50 μl deionized water to the Vitro skin TM On the surface, then add 100 μl of mouthwash product. Mix liquid and spread on Vitro skin TM On the surface. The samples were left overnight at room temperature without a lid. After 18 hours, volunteers were asked to visually inspect the samples and apply Vitro skin TM The amount of moisture present on the...
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