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Phellinus linteus polysaccharide instant effervescent tablets and preparation method thereof

A technology for effervescent tablets and Phellinus linteus, which is applied in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc., to achieve the effects of easy storage and portability, good stability, and good effervescent effect.

Pending Publication Date: 2020-02-11
XUZHOU UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are relatively few developments and researches on Phellinus products in the market, only including Phellinus oral liquid, Phellinus wine, Phellinus acetic acid drink, Phellinus skin care products, etc. Phellinus polysaccharide instant effervescent tablets made of Phellinus polysaccharide The product and its corresponding preparation method have not yet seen relevant reports

Method used

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  • Phellinus linteus polysaccharide instant effervescent tablets and preparation method thereof
  • Phellinus linteus polysaccharide instant effervescent tablets and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] A kind of Phellinus polysaccharide instant effervescent tablet, it is made up of the raw material of following percentage by weight:

[0057] Phellinus polysaccharide (purity greater than or equal to 70%) 28%, acid agent: fumaric acid 22%, alkali agent: sodium bicarbonate 14%, lubricant: sodium stearyl fumarate 1.3%, flavoring agent: erythritol 0.3%, binding agent 4%, moisture absorbing agent: the mixture 0.4% of calcium chloride and gelatin, macrogol 600010%, polyethylene glycol 1000020%, wherein, the mass ratio of calcium chloride and gelatin is 1: 0.2.

[0058] The Phellinus polysaccharide instant effervescent tablet is prepared by the following method:

[0059] (1) Preparation of the first premixed granules:

[0060] The Phellinus polysaccharide raw material, moisture absorbing agent and polyethylene glycol 10000 were respectively pulverized and passed through a 80-mesh sieve, then the polyethylene glycol 10000 was heated and melted (50° C.), and then mixed with Phe...

Embodiment 2

[0069] A kind of Phellinus polysaccharide instant effervescent tablet, it is made up of the raw material of following percentage by weight:

[0070] Phellinus polysaccharide (purity greater than or equal to 70%) 32.5%, acid agent: fumaric acid 25%, alkali agent: sodium bicarbonate 15%, lubricant: sodium stearyl fumarate 1%, flavoring agent: erythritol 0.2%, binding agent 3%, moisture absorbing agent: the mixture 0.3% of calcium chloride and gelatin, polyethylene glycol 60008%, polyethylene glycol 1000015%, wherein, the mass ratio of calcium chloride and gelatin is 1: 0.3.

[0071] The Phellinus polysaccharide instant effervescent tablet is prepared by the following method:

[0072] (1) Preparation of the first premixed granules:

[0073] The Phellinus polysaccharide raw material, moisture absorbing agent and polyethylene glycol 10000 were respectively pulverized and passed through a 80-mesh sieve, then the polyethylene glycol 10000 was heated and melted (50° C.), and then mi...

Embodiment 3

[0082] A kind of Phellinus polysaccharide instant effervescent tablet, it is made up of the raw material of following percentage by weight:

[0083] Phellinus polysaccharide (purity greater than or equal to 70%) 28%, acid agent: citric acid 22%, alkali agent: sodium bicarbonate 14%, lubricant: sodium stearyl fumarate 1.3%, flavoring agent: aspartame 0.3%, binding agent 4%, moisture absorbing agent: the mixture 0.4% of calcium chloride and gelatin, macrogol 600010%, polyethylene glycol 1000020%, wherein, the mass ratio of calcium chloride and gelatin is 1: 0.2.

[0084] The Phellinus polysaccharide instant effervescent tablet is prepared by the following method:

[0085] (1) Preparation of the first premixed granules:

[0086] The Phellinus polysaccharide raw material, moisture absorbing agent and polyethylene glycol 10000 were respectively pulverized and passed through a 80-mesh sieve, then the polyethylene glycol 10000 was heated and melted (50° C.), and then mixed with Phe...

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Abstract

The invention relates to phellinus linteus polysaccharide instant effervescent tablets and a preparation method thereof. The phellinus linteus polysaccharide instant effervescent tablets are preparedfrom the following raw materials in parts by weight: 1-50 parts of phellinus linteus polysaccharides, 15-25 parts of an acid agent, 10-20 parts of an alkaline agent, 0.2-2 parts of a lubricant, 0.1-0.5 part of a flavoring agent, 1-6 parts of an adhesive, 0.2-0.5 part of a moisture absorbent, 5-10 parts of polyethylene glycol 6000 and 10-25 parts of polyethylene glycol 10000. Various raw material types, raw material contents and technological methods are designed, screened and optimized; specifically, the specific moisture absorbent is adopted, the fused polyethylene glycol 10000 is adopted towrap the phellinus igniarius polysaccharide raw material and the moisture absorbent, then tabletting is conducted on the raw material, acidic particles and alkaline particles, and experimental verification proves that the technical problems can be effectively solved.

Description

technical field [0001] The disclosure relates to a Phellinus polysaccharide instant effervescent tablet and a preparation method thereof. Background technique [0002] The information disclosed in this Background section is only intended to increase the understanding of the general background of the disclosure, and is not necessarily to be taken as an acknowledgment or any form of suggestion that the information constitutes prior art that is already known to those skilled in the art. [0003] Phellinus Basidiomycetes, Polyporaceae, Polyporaceae, Phellinus (Phellinus), aliased as Sang Chen, Tree Chicken, Hu Sunyan, Phellinus Sternum, Phellinus Mushroom, Phellinus, Plum Tree bacteria. Modern medical research has found that Phellinus has a variety of pharmacological effects, and has significant curative effects in antibacterial, immune regulation, inhibition of sweat gland secretion, anti-tumor, anti-fibrosis, anti-inflammatory, analgesic, and anti-oxidation. Among them, Phel...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/46A61K9/16A61K47/10A61K47/02A61K47/42A61K31/715A61P35/00
CPCA61K9/0007A61K9/1611A61K9/1641A61K9/1658A61K9/2077A61K31/715A61P35/00
Inventor 陈安徽邵颖秦杰张爱文朱文静岳明宇郭红伟
Owner XUZHOU UNIV OF TECH
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