Lipoic acid tablet and preparation method thereof

A technology of lipoic acid tablets and lipoic acid, which is applied in the fields of anti-toxic agents, pill delivery, and pharmaceutical formulations, can solve the problems of low production cost, high proportion of the main drug, easy sticking of lipoic acid tablets, etc., and achieve high production efficiency , product quality is stable, and the effect of reducing the dose of a single dose
CN112402387APending Publication Date: 2021-02-26SHANDONG QIDU PHARMA
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANDONG QIDU PHARMA
Publication Date
2021-02-26

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Abstract

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a lipoic acid tablet and a preparation method thereof. The tablet comprises a tablet core and afilm coating, the tablet core contains lipoic acid, an adhesive, a filler and a lubricant, and the preparation method comprises the following steps: carrying out dry mixing on a lipoic acid raw material and the adhesive, adding water for granulation, adding the filler and the lubricant after drying, granulating, carrying out total mixing, tabletting, and coating to obtain the product. The lipoicacid tablet is simple in formula composition, has good product stability, good dissolution, and better product quality; the production operation is simple and easy to implement, the variety and dosageof auxiliary materials are small, the main drug proportion is high, the cost is low, the problem that lipoic acid tablets are prone to sticking is solved, and the preparation method is suitable for industrial production.
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Description

technical field

[0001] The invention belongs to the technical field of pharmaceutical preparations, and in particular relates to a lipoic acid tablet and a preparation method thereof. Background technique

[0002] Lipoic acid (lipoic acid), the chemical name is 1,2-dithiolane-3-pentanoic acid, and the molecular formula is C 8 h 12 S 2 o 2 , is a vitamin that is both water-soluble and fat-soluble.

[0003] The chemical structural formula of lipoic acid is as follows:

[0004]

[0005] Lipoic acid is a natural product isolated from pig liver by Reed for the first time in 1951. It participates in the tricarboxylic acid cycle as a coenzyme in the body, not only participates in the metabolic process of glucose, but also directly mediates the distribution of insulin-regulated glucose in peripheral tissues , It has a good preventive effect on chronic complications of diabetes. Lipoic acid enters the cells after being absorbed by the intestines in the body. It has both fat-...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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