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A Measuring System of Microvascular Blood Viscosity Switch Based on Pulse Wave Parameters

A blood viscosity and measurement system technology, applied in the directions of diagnostic recording/measurement, catheter, medical science, etc., can solve the problems of unconsidered, poor correspondence of blood viscosity values ​​of whole blood, differential low blood viscosity model, etc.

Active Publication Date: 2022-03-22
BEIJING UNIV OF TECH
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Problems solved by technology

The blood viscosity detection method described in this method does not consider the influence of factors such as the degree of obesity, blood vessel radius, blood vessel status, and heart blood supply capacity of the test object on blood viscosity, and the test results have certain limitations.
[0010] In 2007, Kaliviotis et al. proposed a method based on a viscoelastic model to describe the mechanical energy of the fluid volume and reflect the blood viscosity value through the rate of change of energy. The model is about 0.1s at the shear rate -1 The above performance is better, at 0.277s -1 The model sensitivity of the shear rate at the position is 0.42. This method establishes a blood viscosity model from the perspective of microscopic hemodynamics. Although it can describe the dynamic blood viscosity value in the body, it is mainly for the study of the difference of blood viscosity in a special disease. , has certain limitations and does not correspond strongly to clinical whole blood viscosity values
However, in terms of theoretical research, there is still a lack of analysis of blood viscosity in vivo, and a comprehensive study of a blood viscosity model with low individual variability that can be transplanted.

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  • A Measuring System of Microvascular Blood Viscosity Switch Based on Pulse Wave Parameters
  • A Measuring System of Microvascular Blood Viscosity Switch Based on Pulse Wave Parameters
  • A Measuring System of Microvascular Blood Viscosity Switch Based on Pulse Wave Parameters

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Embodiment Construction

[0104] A kind of measuring system based on the microvascular blood viscosity switch quantity of pulse wave parameter provided by the present invention is characterized in that, realizes in the digital integrated circuit chip, as memory, arithmetic unit, microprocessor chip, programmable logic device FPGA ,

[0105] Such as figure 1 Shown are the human pulse wave parameter buffer module included in the measurement system, the microvascular blood viscosity logic switch value formation module based on the body mass index, the regression calculation module of the microvascular blood viscosity logic switch value, and the MCU microprocessor. There are four modules in total. The off-line measurement and calculation of wave parameters is input into the MCU microprocessor, and then the human pulse wave parameters are input into the human body pulse wave parameter buffer module under the control of the MCU, and then connected to the body mass index logic switch formation module, and the...

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Abstract

A measurement system of microvascular blood viscosity switching value based on pulse wave parameters belongs to the technical field of medical equipment, in particular, it relates to a measurement system of human microvascular blood viscosity that expresses the pulse wave parameter as a critical value according to the degree of body fat and thinness as a logical switch value , characterized in that the measurement system includes: a human body pulse wave parameter cache module, a body mass index-based microvascular blood viscosity logic switch value forming module, a regression calculation module for the microvascular blood viscosity logic switch value, and an MCU microprocessor. The present invention has the advantages That is, based on the pulse wave, physiological model, and international standards of body mass index, the simulated radius of the physiological blood vessel is obtained by using the multiple regression algorithm to calculate the estimated value of microvascular blood viscosity. This system can use the actual measurable physiological indicators, combined with pulse wave parameter evaluation Cardiovascular safety, self-test is easy to operate, and thresholds are used to indicate the development stages of chronic diseases according to the degree of fatness and thinness, so as to realize the non-invasive detection of microvascular blood viscosity.

Description

technical field [0001] A measurement system of microvascular blood viscosity switching value based on pulse wave parameters belongs to the technical field of medical equipment, in particular, it relates to a measurement system of human microvascular blood viscosity that expresses the pulse wave parameter as a critical value according to the degree of body fat and thinness as a logical switch value . Background technique [0002] Hypertension, hyperglycemia, and hyperlipidemia have become high-risk factors for cardiovascular diseases such as coronary heart disease, atherosclerosis, and myocardial infarction. At the same time, due to the chronic diseases of cardiovascular and cerebrovascular diseases, which have the characteristics of long course, complex etiology, persistence, and no self-healing, real-time and dynamic measurement of blood viscosity is extremely important for the study of the formation, development and prevention of these diseases. Physiological and pathologi...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/02A61B5/00
CPCA61B5/02A61B5/02035A61B5/7235A61B5/7271
Inventor 张松孙葛杨琳王薇薇杨益民李旭雯郝冬梅
Owner BEIJING UNIV OF TECH