Photodynamic diagnosis and therapy integrated alimentary canal capsule endoscopy

A capsule endoscopy and digestive tract technology, applied in the field of medical devices, can solve the problems of complex structure, inability to integrate photodynamic diagnosis and treatment, and large volume, achieving the effect of strong adaptability and improving treatment compliance

Pending Publication Date: 2020-05-12
INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This type of system is large in size and complex in structure, and is only applicable to the superficial cavity of the human body (oral cavity, nasal cavity, vagina, etc.), and cannot realize the integration of photodynamic diagnosis and treatment for tumors in the internal cavity of the human body (such as gastric cancer)

Method used

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  • Photodynamic diagnosis and therapy integrated alimentary canal capsule endoscopy
  • Photodynamic diagnosis and therapy integrated alimentary canal capsule endoscopy
  • Photodynamic diagnosis and therapy integrated alimentary canal capsule endoscopy

Examples

Experimental program
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Embodiment 1

[0030] Gastrointestinal capsule endoscopy integrated with photodynamic diagnosis and treatment

[0031] It includes a camera system, a control system, a battery, and a communication system. The camera system includes a fluorescent camera, a diagnostic LED light source and a therapeutic LED light source.

[0032] The specific structure is as figure 1 As shown on the left, 1 is the diagnostic LED light source, 2 is the treatment LED light source, 3 is the fluorescent camera, 4 is the control system, 5 is the battery, and 6 is the communication system. The positional relationship between the fluorescence camera, the diagnostic LED light source and the treatment LED light source is as follows: figure 1 As shown on the right, the diagnostic LED light source and the treatment LED light source are arranged at intervals radially with the fluorescent camera as the center; the number of the diagnostic LED light source and the treatment LED light source are both 4, arranged at intervals...

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Abstract

The invention provides a photodynamic diagnosis and therapy integrated alimentary canal capsule endoscopy, and belongs to the technical field of medical apparatus and instruments. The capsule endoscopy includes a camera-shooting system, a control system, a battery and a communication system; and the camera-shooting system includes a fluorescent camera, diagnosis LED light sources and treatment LEDlight sources. According to the capsule endoscopy, only a camera-shooting system of an existing magnetically controlled endoscope capsule system needs to be improved, a common optical photography system is replaced with a fluorescent camera-shooting system, and extra equipment does not need to be increased, so that the capsule endoscopy is strong in adaptability; the integration of the diagnosisand therapy on the internal cavities of human bodies can be realized, and one-time accomplishment of photodynamic diagnosis and therapy can be realized as well; as patients has no pain during the treatment with the provided capsule endoscopy, the treatment compliance of the patients can be greatly enhanced; and the provided capsule endoscopy can realize repeated diagnosis/therapy and can detect the treatment processes of the patients.

Description

technical field [0001] The invention belongs to the technical field of medical devices, in particular to a digestive tract capsule endoscope integrated with photodynamic diagnosis and treatment. Background technique [0002] Photodynamic diagnosis (Photodynamic Diagnosis, PDD) is a new type of diagnostic technology, which uses photosensitizing drugs to selectively enrich cancer cells; then irradiates cancer tissue with excitation light to make the enriched photosensitizing drugs produce fluorescence; The intensity and distribution of fluorescence can be analyzed to determine the location and condition of the cancer. For example, the photosensitizing drug ALA is a natural precursor of the heme pathway. Exogenous application of ALA leads to selective accumulation of the heme precursor protoporphyrin IX (PPIX) in cancer cells due to increased porpholinogen deaminase activity and decreased ferrochelatase activity. PPIX is a fluorescent substrate that emits red fluorescence whe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B1/273A61N5/06A61B1/04A61B1/06
CPCA61B1/041A61N5/0603A61N5/062A61B1/0684A61B1/273A61N2005/0651A61N2005/0658A61B1/00158A61B1/043A61N2005/0609A61B1/0655A61B1/00016A61B1/00032A61B1/00186A61B1/00197A61B1/2736A61N2005/0652
Inventor 阴慧娟董晓曦李宏霄黄河张健李迎新
Owner INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
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