Unlock instant, AI-driven research and patent intelligence for your innovation.

Ion-crosslinked polymeric or oligomeric compositions

A polymer composition, the technology of the composition, applied in the fields of ion-doped or ion-crosslinked polymers or oligomers, self-curing composite materials and their preparation and use, which can solve the problems of excessive water absorption, cell adhesion and Poor biological activity, etc.

Pending Publication Date: 2020-05-29
PENN STATE RES FOUND
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, some previous polymer systems have relied on materials such as PEG, alginate, and acrylic acid, all of which lead to excessive water absorption (limiting wet mechanical properties) and poor cell adhesion and bioactivity.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Ion-crosslinked polymeric or oligomeric compositions
  • Ion-crosslinked polymeric or oligomeric compositions
  • Ion-crosslinked polymeric or oligomeric compositions

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0439] Example 1. Preparation and characterization of ion-doped polymer or oligomer compositions.

[0440] Ion-doped polymer or oligomer compositions according to some embodiments described herein were prepared and compared to poly(1,8-octanediol-citric acid) (POC) and ion-impregnated POC.

[0441] The preparation method of poly(1,8-octanediol-citric acid) (POC) is as Figure 5 shown. Using Ca(NO 3 ) 2 , CaCO 3 , CaBr 2 , CaI 2 , NaCl, LiCl, KCl, MgCl 2 , SrCl 2 , ZnCl 2 、NiCl 2 , CuCl 2 , AlCl 3 and FeCl 3 pass Image 6 The method shown prepares the ion-immersion POC.

[0442] Measuring the mechanical properties of POCs and ion-doped POCs, such as Figure 7-17 shown. specifically, Figure 7 is to be doped with CaCl 2 , CaCit, Ca(NO 3 ) 2 , CaCO 3 , CaBr 2 and CaI 2 A histogram comparing the stress (in MPa) of the polymer to the stress (in MPa) of the POC. Figure 8 is to be doped with CaCl 2 , CaCit, Ca(NO 3 ) 2 , CaCO 3 , CaBr 2 and CaI 2 A hist...

Embodiment 2

[0446] Example 2. Preparation and characterization of self-curing citrate-based composites

[0447] Magnesia / POC self-curing compositions were prepared using the method described above. Figure 26 The setting times at various temperatures are shown for compositions prepared using POC at a concentration of 30% by weight and magnesium oxide at a concentration of 10% by weight in ethanol. Figure 26 Demonstrated curing potential at room temperature and temperature accelerated conditions.

[0448] Figure 27 Curing at different temperatures of compositions prepared using 30% or 40% by weight POC in ethanol, 10% by weight magnesium oxide in the presence or absence of 20% hydroxyapatite (HA) is shown time. Figure 27 It was shown that compositions prepared using POC at a concentration of 40% by weight as well as compositions prepared in the presence of HA showed accelerated curing. The setting time is determined rheologically, eg, at room temperature, using a Broofield cone and ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

In one aspect, compositions are described herein, and in another aspect methods are described herein. In some embodiments, a polymerizable composition described herein comprises (i) one or more alkoxylated or alkenoxylated, or non-alkoxylated and non- alkenoxylated, citric acid, citrate, or ester / amide of citric acid; (ii) a polyol or polyamine such as a diol or diamine; and (iii) at least one ofan associated or dissociated salt comprising a monovalent, divalent, or trivalent metal cation. In some cases, the polymerizable composition comprises additional monomers. In some cases, a compositiondescribed herein comprises a polymer or oligomer formed from a polymerizable compositions described herein. In other instances, a self-setting composite material comprising a mixture of a metal oxidecrosslinker and a citrate based polymer, as well as methods of preparing same, are described herein.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to U.S. Provisional Application No. 62 / 517,377, filed June 9, 2017, and U.S. Provisional Application No. 62 / 517,418, filed June 9, 2017. Each of the foregoing applications is incorporated herein by reference in its entirety. technical field [0003] The present disclosure relates to polymerizable compositions and polymer or oligomer compositions, as well as methods of making polymers or oligomers from the polymerizable compositions. More specifically, the present disclosure relates to ionically doped or ionically crosslinked polymers or oligomers. The present application also relates to self-curing composite materials and methods of making and using the same. Background technique [0004] In recent years, biodegradable polymeric or oligomeric materials have found increasing use in a wide range of biomedical engineering applications, for example, tissue engineering, drug delivery, woun...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C08G59/68C08G63/82C08L63/00
CPCC08G63/12C08G63/52C08G63/668C08G18/343C08G18/3203C08G18/73C08G18/755C08G18/7621C08G18/7671C08G18/4833C08G18/4825C08G63/6854C08G63/81C08L67/025C08L67/06C08L2203/02C08L2312/00C08K3/105C08L67/04
Inventor 杨建伊森·格哈德
Owner PENN STATE RES FOUND