Medical oral cavity antibacterial composition, preparation method and application thereof

A composition and oral technology, applied in the field of medical bacteriostatic compositions, can solve the problems of not being able to achieve an ideal cleaning effect, easy to breed bacteria and the like

Pending Publication Date: 2020-06-12
五赫兹(厦门)医疗用品有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since the interval between morning and evening brushing is as long as 12 hours, simple tea or mouthwash during the day cannot achieve the ideal cleaning effect, resulting in the residues contained in the oral cavity that are prone to the growth of bacteria, causing bad breath and oral ulcers Dental diseases such as oral diseases and periodontitis

Method used

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  • Medical oral cavity antibacterial composition, preparation method and application thereof
  • Medical oral cavity antibacterial composition, preparation method and application thereof
  • Medical oral cavity antibacterial composition, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] The components and contents of each component of oral antibacterial mouthwash are shown in Table 1.

[0049] Table 1.

[0050]

[0051]

[0052] The preparation process of oral antibacterial mouthwash is as follows:

[0053] (1) Add polyhexamethylene biguanide, glycerin, sucralose, sodium citrate, ginkgo biloba extract, honeysuckle extract, sage leaf extract, gardenia fruit extract to water, stir at room temperature for 10 Minutes to obtain mixture one;

[0054] (2) Stir glycerin, PEG-60 hydrogenated castor oil, phenoxyethanol, ethanol, juniper essential oil, and menthol to obtain mixture 2;

[0055] (3) Mixture 2 was added to Mixture 1, and stirred at room temperature for 20 minutes to obtain an oral antibacterial gel.

[0056] The oral antibacterial mouthwash provided in this example is a colorless transparent liquid with a pH value of 4.80, no precipitation, particles and flocs, and has aromaticity.

Embodiment 2

[0058] The components and contents of each component of the medical oral antibacterial mouthwash are shown in Table 2.

[0059] Table 2.

[0060]

[0061]

[0062] The preparation process of oral antibacterial mouthwash is with embodiment 1.

[0063] The oral antibacterial mouthwash provided in this example is a colorless transparent liquid with a pH value of 4.90, no precipitation, particles and flocs, and has aromaticity.

Embodiment 3

[0065] The components and contents of each component of oral antibacterial mouthwash are shown in Table 3.

[0066] table 3.

[0067]

[0068]

[0069] The preparation process of oral antibacterial mouthwash is with embodiment 1.

[0070] The antibacterial mouthwash for medical oral cavity provided in this example is a colorless transparent liquid with a pH value of 5.0, no precipitation, particles and flocs, and has aroma.

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PUM

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Abstract

The invention discloses a medical oral cavity antibacterial composition, a preparation method and application thereof. The composition is prepared from the following components in parts by weight: (2to 20)*10<-4 > parts of polyhexamethylene biguanide, 15 to 30 parts of cypress essential oil and 0.01 to 20 parts of a Chinese herbal medicine extract, wherein the Chinese herbal medicine extract is selected from one, two or more of a ginkgo leaf extract, a honeysuckle extract, a salvia officinalis extract and a gardenia fruit extract. The product provided by the invention has good stability and excellent antibacterial and bacteriostatic ability, especially can effectively inhibit porphyromonas gingivalis in the oral cavity, can inhibit and relieve periodontitis, and can be prepared into mouthwash and gel, wherein the preparation can reach the medical grade.

Description

technical field [0001] The invention belongs to the field of medical antibacterial compositions, in particular to a medical oral antibacterial composition and its preparation method and application. Background technique [0002] Oral health is closely related to physical health. Modern medicine has proved that most oral diseases are related to bacteria, such as oral ulcers and periodontitis. Daily necessary oral care can effectively prevent the occurrence of various oral diseases, and keeping the oral cavity clean and healthy is an important means to prevent the occurrence of diseases. [0003] At present, people generally adopt the mode of brushing teeth sooner or later, tea or salt water mouthwash after meal to carry out oral care and cleaning. However, since the interval between morning and evening brushing is as long as 12 hours, simple tea or mouthwash during the day cannot achieve the ideal cleaning effect, resulting in the residues contained in the oral cavity that a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/14A61K36/744A61P1/02A61P31/04A61K31/785
CPCA61K31/785A61K36/14A61K36/16A61K36/355A61K36/537A61K36/744A61P1/02A61P31/04A61K2300/00
Inventor 张立波
Owner 五赫兹(厦门)医疗用品有限公司
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