Multipurpose magnetic sensitive immunoassay micro-fluidic chip and using method thereof

A microfluidic chip, immunoassay technology, applied in the direction of analyzing materials, material magnetic variables, material inspection products, etc., can solve the problems of complex structure of microfluidic chips, difficult to reuse, etc., to facilitate mass production and commercial use, The effect of reducing difficulty and cost and improving accuracy

Active Publication Date: 2020-06-19
XI AN JIAOTONG UNIV
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  • Claims
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Problems solved by technology

[0005] The purpose of the present invention is to provide a multi-purpose magnetic-sensitivity immunoassay microfluidic chip and its use method to solve the problem that the structure of this type of microfluidic chip is complex and difficult to reuse

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  • Multipurpose magnetic sensitive immunoassay micro-fluidic chip and using method thereof
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  • Multipurpose magnetic sensitive immunoassay micro-fluidic chip and using method thereof

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Embodiment Construction

[0036] The present invention will be further described in detail below in conjunction with specific embodiments, which are explanations of the present invention rather than limitations.

[0037] The invention provides a multi-purpose magnetic-sensitivity immunoassay microfluidic chip and its use method, which simplifies the structural design and facilitates multi-purpose and repeated use. A specific embodiment is introduced below.

[0038] Such as figure 1 and figure 2 As shown, a multi-purpose magnetic-sensitivity immunoassay microfluidic chip of the present invention includes a magnetic-sensitivity biosensing chip 1 , a microfluidic chip upper cover 2 and a microfluidic chip negative 3 .

[0039] Such as image 3As shown, the magnetic-sensitive biosensor chip 1 is composed of a magnetic-sensitive sensor array 14 and a PCB adapter board 11, with a width of 10-14 mm, a length of 16-20 mm, and a thickness of about 2 mm. The silicon-based magnetic sensor array 14 is bonded ...

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Abstract

The invention provides a multipurpose magnetic sensitive immunoassay micro-fluidic chip and a using method thereof. The design that a magnetic sensitive biosensor chip is embedded outside the upper cover of the micro-fluidic chip is adopted, the overall structure is simplified, and the positioning and assembling precision requirements of the magnetic sensitive biosensor chip and the micro-fluidicchip are lowered; by adopting a mode of externally embedding the magnetic sensitive biosensor chip, the magnetic sensitive biosensor chip is in direct contact with a reagent, the contact between a detection circuit and the biological reagent is reduced, the interference is reduced, and the accuracy of a result is improved; a mode of externally embedding a magnetic sensitive biosensor chip is adopted, the magnetic sensitive biosensor chip is convenient to mount and dismount, the magnetic sensitive biosensor chip is convenient to replace after being used, the same micro-fluidic chip can be repeatedly used or used for detection of various different purposes conveniently, and the cost of the micro-fluidic chip is generally obviously higher than that of a magnetic sensitive biosensor, so that the cost can be greatly reduced by repeated use of the micro-fluidic chip.

Description

technical field [0001] The invention relates to a microfluidic chip, in particular to a multipurpose magnetic-sensitivity immunoassay microfluidic chip and a method for using the chip. Background technique [0002] Microfluidic chips, also known as laboratories on a chip, are widely used in modern biomedical testing. It can automate a series of operations such as sample preparation, mixing, transfer, separation, and extraction involved in biology, chemistry, and medicine through various micro-nano-sized chambers, flow channels, and structures under the action of external driving forces, quickly, and efficiently. Accurate completion, with the characteristics of easy operation, less pollution, fast speed, etc., it has a good application prospect in medical testing, material preparation, food safety, environmental monitoring and other fields. [0003] Magnetosensitivity immunoassay is a method of capturing magnetic Bead-labeled antigen, detect the magnetic signal of nano-magn...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/543G01N33/53G01N27/74
CPCG01N27/74G01N33/5302G01N33/54326
Inventor 彭年才张航张朋胡飞
Owner XI AN JIAOTONG UNIV
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