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Kit for detecting IgM antibody for resisting novel coronavirus SARS-CoV-2 in sample

A technology for detecting samples and coronaviruses, applied in biological testing, material inspection products, measuring devices, etc., can solve the problems of difficult sample collection operations, shortening detection time, and difficulty in sample storage, achieving low machine dependence and shortening detection time. , make up for the time-consuming effect

Pending Publication Date: 2020-07-10
中科欧蒙未一(北京)医学技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Therefore, it is very necessary to develop a new kit for detecting IgM antibodies against the new coronavirus SARS-CoV-2 in samples, so as to avoid the difficulties in sample collection in nucleic acid detection, and the collected samples cannot accurately reflect suspected pneumonia. It has the advantages of short operation time, low cost, and low dependence on machines, and it can also detect S protein and N protein at the same time, which not only reduces the detection cost, but also significantly shortens the time. Detection time and improved detection efficiency and detection accuracy

Method used

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  • Kit for detecting IgM antibody for resisting novel coronavirus SARS-CoV-2 in sample
  • Kit for detecting IgM antibody for resisting novel coronavirus SARS-CoV-2 in sample
  • Kit for detecting IgM antibody for resisting novel coronavirus SARS-CoV-2 in sample

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Embodiment approach 1

[0114] Embodiment 1. is used for detecting the device of the IgM antibody of anti-new coronavirus SARS-CoV-2 in the sample with immunoblotting method, it comprises:

[0115] backing; and

[0116] A solid phase support coated with a purified S protein antigen, a solid phase support coated with a purified N protein antigen, and a solid phase support coated with an IgM antibody that are sequentially arranged on the backing .

Embodiment approach 2

[0117] Embodiment 2. is used for the device of anti-new coronavirus SARS-CoV-2 IgM antibody in the detection sample with immunoblotting method, it comprises:

[0118] backing; and

[0119] A solid phase support coated with a purified N protein antigen, a solid phase support coated with a purified S protein antigen, and a solid phase support coated with an IgM antibody that are sequentially arranged on the backing .

Embodiment approach 3

[0120] Embodiment 3. The device according to embodiment 1 or 2, wherein on the backing, downstream of the solid phase support coated with IgM antibody, there is also a Handle label separated by solid support.

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Abstract

The invention discloses a kit for detecting an IgM antibody for resisting a novel coronavirus SARS-CoV-2 in a sample. The invention further discloses an application of the kit in preparation of a product for diagnosing novel coronavirus SARS-CoV-2 infection. The kit provided by the invention has the advantages of short operation time, low cost, low dependence on a machine, capability of simultaneously carrying out detection by utilizing S protein and N protein, low detection cost, high detection efficiency, high detection accuracy rate and the like.

Description

technical field [0001] The application relates to a kit for detecting IgM antibodies against novel coronavirus SARS-CoV-2 in a sample. More specifically, the application relates to a device for detecting anti-new coronavirus SARS-CoV-2 IgM antibody in a sample by Western blotting, and a device for detecting anti-new coronavirus SARS-CoV-2 in a sample by Western blotting. A kit for IgM antibody, a method for detecting IgM antibody against novel coronavirus SARS-CoV-2 in a sample by immunoblotting, a combination of purified S protein antigen and purified N protein antigen or the device or the kit in a test sample The use of anti-new coronavirus SARS-CoV-2 IgM antibody, and the combination of purified S protein antigen and purified N protein antigen or the device or the kit in the preparation of products for diagnosing new coronavirus SARS-CoV-2 infection the use of. Background technique [0002] Since December 2019, there have been outbreaks of pneumonia caused by a new type...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/68G01N33/569G01N33/545G01N33/543
CPCG01N33/6854G01N33/56983G01N33/545G01N33/54366G01N2333/165G01N2469/20
Inventor 张志栋张凯李雁飞
Owner 中科欧蒙未一(北京)医学技术有限公司
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