Application of full-suspension duck embryo retinal cells in eggs drop syndrome vaccine
A technology for retinal cells and egg production decline, applied in the field of poultry vaccines, can solve problems such as low HA titer, and achieve the effects of clear cell sources, high economic benefits, market prospects, and high virus titers
Pending Publication Date: 2020-09-18
成都史纪生物制药有限公司
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It has also been reported that EB66 cells were used to prepare chicken egg production drop syndrome vaccine, but the virus titer
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The invention relates to the technical field of poultry vaccine, in particular to an application of full-suspension duck embryo retinal cells in eggs drop syndrome vaccine. The application of the full-suspension duck embryo retinal cells in the eggs drop syndrome vaccine comprises the following steps of enabling a K-11 strain virus to be inoculated into the full-suspension duck embryo retinal cells for culturing to obtain an antigen solution of the eggs drop syndrome virus, and performing mixing on the antigen solution of the eggs drop syndrome virus with a vaccine adjuvant to obtain the eggsdrop syndrome vaccine. The full-suspension duck embryo retinal cells are applied to the eggs drop syndrome vaccine, so that the vaccine titer can be improved, and the cost is low.
Description
technical field [0001] The invention relates to the technical field of poultry vaccines, in particular to the application of fully suspended duck embryo retinal cells in chicken egg drop syndrome vaccines. Background technique [0002] Eggs drop syndrome (EDS) is a common infectious virus in laying hens caused by Eggsdrop syndrome virus (EDSV). Infected chickens will severely reduce egg production and affect egg quality. Affected chickens mainly show symptoms such as mass drop in egg production rate, abnormal eggshell, deformed egg body, and poor egg quality. The disease can reduce the laying rate of laying hens by 30-50%, the breakage rate of eggs reaches 40%, and shellless eggs and soft-shell eggs can reach 15%, causing serious economic losses to the chicken industry. [0003] At present, the production of vaccines related to chicken egg drop syndrome in my country mainly adopts inoculation of duck embryos to prepare vaccines. Because SPF duck embryos are expensive and t...
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Login to view more IPC IPC(8): A61K39/235A61P31/20
CPCA61K39/12A61P31/20A61K2039/552C12N2710/10234
Inventor 邢刚丁莉李成山岳丰雄左榕琳肖倩潘倩
Owner 成都史纪生物制药有限公司
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