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Compound allicin soft capsule and preparation and packaging method thereof

A technology of allicin and garlic, applied in the field of clinical application, can solve the problems of increased toxic side effects, large toxic side effects, strong drug resistance, etc., and achieve the effects of avoiding large toxic side effects, definite curative effect, and clear mechanism of action

Inactive Publication Date: 2020-09-25
GUANGZHOU HONGKANG PHARM TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] With the development of population aging and the abuse of antibiotics, the number of common clinical superinfections and superinfections is increasing day by day. Commonly used antibiotics such as penicillin antibiotics and cephalosporin antibiotics are artificially synthesized modified compounds, which have strong drug resistance and toxicity. Disadvantages of large side effects. Most of the common clinical chronic diseases are elderly patients. Most of these patients have multiple organ diseases combined with liver and kidney insufficiency. The combination of antibiotics, lipid-lowering drugs and other drugs increases the toxicity and side effects, and the prognosis is poor. Therefore, it is necessary to develop a broad-spectrum antibacterial drug with definite curative effect, long-term use and no side effects

Method used

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  • Compound allicin soft capsule and preparation and packaging method thereof
  • Compound allicin soft capsule and preparation and packaging method thereof

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preparation example Construction

[0026] A preparation and packaging method for compound allicin soft capsules, comprising the following steps:

[0027] S1. Prepare solution 1: weigh allicin according to the formula ratio, add part of the water, heat and stir until completely dissolved;

[0028] S2. Prepare solution 2: according to the formula ratio, weigh houttuyfonate, add some water, mix evenly, and stir until completely dissolved;

[0029] S3. Mixing and stirring: according to the formula ratio, add the quantitative solution 1 into the quantitative solution 2, and stir until completely dissolved to obtain the mixed solution;

[0030] S4. Preparation of capsule skin glue: according to the formula ratio, weigh gelatin, plasticizer, additive and water, first put the gelatin in water, soak it to make it expand, after the gelatin is melted, mix the plasticizer and additive Add together, then mix and stir evenly to obtain capsule skin glue;

[0031] S5. Preparation of capsule: apply the capsule gel obtained in...

Embodiment 1

[0034] Embodiment 1, a kind of compound allicin soft capsule, is made up of capsule content and capsule skin, and each component of described capsule content is calculated according to its mass percentage: allicin: 60% and houttuyfondin: 40%, The components of the capsule skin are calculated according to their mass percentages: gelatin: 15%, plasticizer: 5%, additives: 5% and water: 75%.

[0035]

[0036] A preparation and packaging method for compound allicin soft capsules, comprising the following steps:

[0037] S1. Prepare solution 1: weigh allicin according to the formula ratio, add part of the water, heat and stir until completely dissolved;

[0038] S2. Prepare solution 2: according to the formula ratio, weigh houttuyfonate, add some water, mix evenly, and stir until completely dissolved;

[0039] S3. Mixing and stirring: according to the formula ratio, add the quantitative solution 1 into the quantitative solution 2, and stir until completely dissolved to obtain th...

Embodiment 2

[0044] Embodiment 2, a kind of compound allicin soft capsule, is made up of capsule content and capsule skin, and each component of described capsule content is counted by its mass percentage: allicin: 65% and houttuyfondin: 35%, The components of the capsule skin are calculated according to their mass percentages: gelatin: 15%, plasticizer: 5%, additives: 5% and water: 75%.

[0045]

[0046] A preparation and packaging method for compound allicin soft capsules, comprising the following steps:

[0047] S1. Prepare solution 1: weigh allicin according to the formula ratio, add part of the water, heat and stir until completely dissolved;

[0048] S2. Prepare solution 2: according to the formula ratio, weigh houttuyfonate, add some water, mix evenly, and stir until completely dissolved;

[0049] S3. Mixing and stirring: according to the formula ratio, add the quantitative solution 1 into the quantitative solution 2, and stir until completely dissolved to obtain the mixed solut...

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Abstract

The invention discloses a compound allicin soft capsule and a preparation and packaging method thereof. The compound allicin soft capsule is composed of a capsule content and a capsule skin. The capsule content comprises the following components in percentage by mass: allicin: 1%-65% of allicin and 1%-55% of houttuynin; the capsule skin comprises the following components in percentage by mass: 10%-22% of a rubber excipient, 1%-10% of a plasticizer, 1%-10% of an additive and 50%-80% of water. The compound allicin soft capsule has the beneficial effect that the allicin and houttuynin are sully mixed in a certain ratio, so that the effects cooperate with each other, a broad-spectrum antibacterial drug which has exact therapeutic effects, can be taken for a long time and has no toxic or side effects is obtained, meanwhile, the drug components are clear, the action mechanism is explicit, and the defects of complex components of traditional Chinese medicines and unknown pharmacological mechanisms are avoided. In addition, the defects that chemical drugs have large toxic and side effects on the liver and spleen and cannot be taken for a long term are overcome.

Description

technical field [0001] The invention relates to the technical field of clinical application, in particular to a compound allicin soft capsule and a preparation and packaging method thereof. Background technique [0002] With the development of population aging and the abuse of antibiotics, the number of common clinical superinfections and superinfections is increasing day by day. Commonly used antibiotics such as penicillin antibiotics and cephalosporin antibiotics are artificially synthesized modified compounds, which have strong drug resistance and toxicity. Disadvantages of large side effects. Most of the common clinical chronic diseases are elderly patients. Most of these patients have multiple organ diseases combined with liver and kidney insufficiency. The combination of antibiotics, lipid-lowering drugs and other drugs increases the toxicity and side effects, and the prognosis is poor. Therefore, it is necessary to develop a broad-spectrum antibacterial drug with defi...

Claims

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Application Information

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IPC IPC(8): A61K31/255A61K31/185A61K9/48A61K47/42A61P11/00A61P31/14A61P31/04A61P31/10
CPCA61K9/4816A61K9/4825A61K9/4866A61K31/185A61K31/255A61P11/00A61P31/04A61P31/10A61P31/14A61K2300/00
Inventor 肖军宏
Owner GUANGZHOU HONGKANG PHARM TECH CO LTD
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