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Application of traditional Chinese medicine composition in preparation of medicine for preventing and treating coronavirus complicated with lung injury

A technology of coronavirus and composition, which is applied in the application field of traditional Chinese medicine composition in the preparation of drugs for preventing and treating coronavirus combined with lung injury, and can solve problems such as life and health hazards of patients

Inactive Publication Date: 2020-10-23
GUANGDONG LEIYUNSHANG PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no effective treatment drug for the new coronavirus SARS-CoV-2 on the market, which brings great harm to the life and health of patients

Method used

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  • Application of traditional Chinese medicine composition in preparation of medicine for preventing and treating coronavirus complicated with lung injury

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] 1. Case selection:

[0025] Collect 20 patients (10 males and 10 males and 37-78 years old) diagnosed with the novel coronavirus (SARS-CoV-2). CT scans of 20 patients showed patchy ground-glass opacities under the pleura of both lungs and thickened lung markings. , double lung consolidation shadow increased, obvious different degrees of lung inflammation and lung injury lesions, accompanied by cough and fever symptoms. Biochemical indicators showed that the levels of lymphocytes, percentage of lymphocytes, neutrophils and CD8 cells were significantly lower than normal, and the blood oxygen level was 87-96%.

[0026] 2. Treatment method:

[0027] In addition to 20 routine cases doing basic oxygen supply and vital signs maintenance treatment, the traditional Chinese medicine composition of the present invention (Bufei Huoxue Capsules, Z20030063) was taken orally, 4 capsules (0.35g per capsule), 3 times a day, continuous medication for 1, After 2 weeks, observe the curat...

Embodiment 2

[0031] Female patient Zhou, 40 years old, has a history of contact with the epidemic area in Wuhan, fever, and a positive 2019-nCoV nucleic acid test. Combined with CT examination, she was diagnosed as a patient with a new type of coronavirus (SARS-CoV-2). Give basic vital signs nutrition and oxygen inhalation maintenance treatment, take Bufei Huoxue Capsules of the present invention simultaneously, Chinese medicine standard word Z20030063, 4 capsules (each 0.35g), every day 3 times, after continuous medication 1 week and 2 weeks, significantly less coughing, such as figure 1 As shown, A, B, and C are the CT lung window images of the same level before treatment, after 1 week of treatment, and after 2 weeks of treatment, respectively. The inflammation range of the left lower lobe of the left lung decreased in the first week and the second week, and the clinical symptoms were alleviated. Cough, low blood oxygen symptoms were relieved. There was no deterioration to severe or cri...

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Abstract

The invention discloses application of a traditional Chinese medicine composition in preparation of a medicine for preventing and treating novel coronavirus complicated with lung injury. The intervention effect of the traditional Chinese medicine composition on novel coronavirus (SARS-CoV-2) is screened, and a clinical experiment result shows that the traditional Chinese medicine composition has agood effect of inhibiting lung injury and lung fibrosis caused by novel coronavirus (SARS-CoV-2). The traditional Chinese medicine composition can improve the levels of albumin, lymphocyte, lymphocyte percentage, neutrophil and CD8 cells and reduce the levels of C reactive protein and lactate dehydrogenase, the novel coronavirus complicated with lung injury can be treated in an assisted manner, and a recovery rate can be improved.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to the application of the traditional Chinese medicine composition in the preparation of medicines for preventing and treating coronavirus combined with lung injury. Background technique [0002] On February 11, the International Committee on Taxonomy of Viruses (ICTV) announced the official name of the new coronavirus as severe acute respiratory syndrome coronavirus 2 (severe acute respiratory syndrome coronavirus 2, referred to as SARS-CoV-2). [0003] The imaging manifestations of the new coronavirus showed multiple small patchy shadows and interstitial changes in the early stage, especially in the extrapulmonary zone. Then it develops into multiple ground-glass opacities and infiltrates in both lungs. In severe cases, lung consolidation may occur, and pleural effusion is rare. The novel coronavirus can cause diffuse alveolar damage, hyaline membrane formation, and p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K36/65A61P31/14A61P11/00
CPCA61K36/481A61K36/487A61K36/65A61K36/71A61K2236/33A61K2236/39A61P11/00A61P31/14A61K2300/00
Inventor 李全李志斌文春义赵钰何宇辉
Owner GUANGDONG LEIYUNSHANG PHARM CO LTD
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